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Good Practice in Postoperative and Procedural Pain Management ...

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most effective. There are a number of less pa<strong>in</strong>fulalternatives to simple wound suture <strong>in</strong> the awakepatient: Tissue adhesives <strong>in</strong> simple low-tension wounds<strong>and</strong> the hair apposition technique (HAT) <strong>in</strong> scalp lacerationsare examples.Also see section 4.0 <strong>and</strong> 4.2 for general considerations<strong>in</strong> procedural pa<strong>in</strong> management.<strong>Good</strong> practice po<strong>in</strong>tFor extensive wounds or children who are very anxiousconsider sedation or general anesthesia.RecommendationsFor repair of simple low-tension lacerations, tissue adhesivesshould be considered as they are less pa<strong>in</strong>ful, quickto use, <strong>and</strong> have a similar cosmetic outcome to sutures oradhesive sk<strong>in</strong> closures (steri-strips): Grade A (146–148).Topical anesthetic preparations, for example, LAT (lidoca<strong>in</strong>e–adrenal<strong>in</strong>e–tetraca<strong>in</strong>e)if available, can be used <strong>in</strong>preference to <strong>in</strong>jected LA, as they are less pa<strong>in</strong>ful toapply; it is not necessary to use a preparation conta<strong>in</strong><strong>in</strong>gcoca<strong>in</strong>e: Grade A (149–153).Buffer<strong>in</strong>g <strong>in</strong>jected lidoca<strong>in</strong>e with sodium bicarbonateshould be considered: Grade A (88).‘HAT’ should be considered for scalp lacerations. It isless pa<strong>in</strong>ful than sutur<strong>in</strong>g, does not require shav<strong>in</strong>g, <strong>and</strong>produces a similar outcome: Grade B (154).If <strong>in</strong>jected lidoca<strong>in</strong>e is used, pretreatment of the woundwith a topical anesthetic preparation, for example, lidoca<strong>in</strong>e–adrenal<strong>in</strong>e–tetraca<strong>in</strong>e(LAT) gel, reduces the pa<strong>in</strong>of subsequent <strong>in</strong>jection: Grade B (155,156).50% nitrous oxide reduces pa<strong>in</strong> <strong>and</strong> anxiety dur<strong>in</strong>g lacerationrepair: Grade B (157–159).EvidenceLaceration repair has been relatively well studied <strong>in</strong>children. There are a number of alternatives to simplewound suture <strong>in</strong> the awake patient. Tissue adhesives <strong>in</strong>simple low-tension wounds <strong>and</strong> the hair appositiontechnique (HAT) <strong>in</strong> scalp lacerations are less pa<strong>in</strong>fulalternatives (147,154). A number of topical local anestheticmixtures are available; they can give equivalentanalgesia to <strong>in</strong>filtrated local anesthetic <strong>and</strong> are lesspa<strong>in</strong>ful to apply although a recent systematic review <strong>in</strong>adults <strong>and</strong> children concluded that there was <strong>in</strong>sufficientevidence to unreservedly recommend topical LA<strong>in</strong> preference to <strong>in</strong>jected LA (82,153). A systematicreview <strong>in</strong>clud<strong>in</strong>g trials <strong>in</strong> adults <strong>and</strong> children found that‘buffer<strong>in</strong>g’ local anesthetics with sodium bicarbonatesignificantly reduces the pa<strong>in</strong> of <strong>in</strong>jection (88). Nitrousoxide has been shown to be effective <strong>in</strong> reduc<strong>in</strong>g pa<strong>in</strong>,anxiety, <strong>and</strong> distress <strong>in</strong> cooperative children (157,158).See section 6.7 for <strong>in</strong>formation on the use of nitrousoxide. Psychological techniques such as distraction <strong>and</strong>relaxation are also likely to be useful (85).Analgesia Table 4.3.7 Repair of lacerations <strong>in</strong> childrenDirectevidenceIndirectevidenceLocal anesthesia Topical 1++Infiltration 1++Buffered 1++<strong>in</strong>filtration50% nitrous oxide 1+Procedure modification 1++Psychological <strong>in</strong>tervention 1++4.3.8 Dress<strong>in</strong>g changes <strong>in</strong> the burned childChildren with burns often require repeated, oftenextremely pa<strong>in</strong>ful, dress<strong>in</strong>g changes. Children withsevere burns are normally cared for <strong>in</strong> a specialist unit,but some children will be seen <strong>in</strong> Emergency Departments.Initial dress<strong>in</strong>g changes are likely to be performedunder general anesthesia, <strong>and</strong> if childrenrema<strong>in</strong> very distressed, this option may be favored forsubsequent procedures. Sedation is sometimes used tosupplement analgesia for burns dress<strong>in</strong>gs, see NICEGuidel<strong>in</strong>e CG112 ‘Sedation <strong>in</strong> Children <strong>and</strong> YoungPeople’ available at: http://www.nice.org.uk/CG112. Inthe early stages of burn pa<strong>in</strong> management, childrenmay require cont<strong>in</strong>uous <strong>in</strong>fusion of potent opioidssuch as morph<strong>in</strong>e, <strong>and</strong> additional analgesia will berequired prior to dress<strong>in</strong>g changes (160).Both pharmacological <strong>and</strong> nonpharmacological techniquesshould be used <strong>in</strong> the management of pa<strong>in</strong>fuldress<strong>in</strong>g changes, see section 4.0, 4.1, <strong>and</strong> 4.2 for adviceon the general management of pa<strong>in</strong>ful procedures.RecommendationsPotent opioid analgesia given by oral, transmucosal, ornasal routes accord<strong>in</strong>g to patient preference <strong>and</strong> availabilityof suitable preparations should be considered fordress<strong>in</strong>g changes <strong>in</strong> burned children: Grade A (161–164).Nonpharmacological therapies such as distraction <strong>and</strong>relaxation should be considered as part of pa<strong>in</strong> managementfor dress<strong>in</strong>g changes <strong>in</strong> burned children: Grade B(165–170).26 ª 2012 Blackwell Publish<strong>in</strong>g Ltd, Pediatric Anesthesia, 22 (Suppl. 1), 1–79

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