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Good Practice in Postoperative and Procedural Pain Management ...

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Analgesia Table 5.6.4 Urological SurgeryAgentTechniqueDirectevidenceLA Epidural 1)LA + opioid Epidural 1)LA Caudal epidural 1)LA Paravertebral block 2)LA a Wound <strong>in</strong>filtration 3Opioid a Intravenous 3 1+NSAID a 3 1+Paracetamol a 3 1+a As part of a multimodal technique.5.7 Laparoscopic surgeryIndirectevidenceThere has been a dramatic <strong>in</strong>crease <strong>in</strong> the amount ofpediatric laparoscopic surgery <strong>in</strong> the last decade. Thisis performed ma<strong>in</strong>ly through the body cavities (chest<strong>and</strong> abdomen) or potential spaces. Ingu<strong>in</strong>al herniarepair, appendicectomy, fundoplication, urological <strong>and</strong>adrenal surgery are examples. For general managementof postoperative pa<strong>in</strong>, see section 5.1.<strong>Good</strong> practice po<strong>in</strong>tsInfiltration of port sites with LA as part of a multimodalanalgesic strategy may reduce postoperativepa<strong>in</strong> follow<strong>in</strong>g laparoscopy.Although overall postoperative analgesic requirementsappear to be reduced follow<strong>in</strong>g laparoscopy, pa<strong>in</strong> maybe equivalent to the equivalent open procedure <strong>in</strong>some circumstances, particularly dur<strong>in</strong>g the first 24 h.EvidenceAdvantages of laparoscopic surgery may <strong>in</strong>clude fasterrecovery <strong>and</strong> overall reduction <strong>in</strong> pa<strong>in</strong> <strong>and</strong> use of opioidanalgesia <strong>in</strong> comparison with the open surgicalcounterpart (246,267–272). Although the overall durationof postoperative pa<strong>in</strong> appears to be reduced, analgesicrequirements may be at least as great on the firstpostoperative day as the equivalent open procedure(261,267,273–275). The use of robotic laparoscopictechniques may also decrease postoperative opioidrequirements after ureteric reimplantation surgery(276). The anatomical approach to laparoscopic surgeryhas not been shown to effect analgesic requirements(277,278).Multimodal analgesia <strong>in</strong>clud<strong>in</strong>g LA <strong>in</strong>filtration, opioid,NSAID, <strong>and</strong> paracetamol is suitable, <strong>and</strong> the useof carefully designed protocols may improve efficacy(279). Dem<strong>and</strong>-led opioid regimens such as PCA orNCA are feasible <strong>and</strong> effective for some procedures<strong>and</strong> require further evaluation (246,262).LA <strong>in</strong>filtration of port sites when comb<strong>in</strong>ed withNSAID provided equivalent analgesia to caudal blockfor m<strong>in</strong>or diagnostic <strong>and</strong> therapeutic laparoscopic procedures<strong>and</strong> to TAP block follow<strong>in</strong>g appendicectomy(280,281). Use of aerosolised bupivaca<strong>in</strong>e after port<strong>in</strong>sertion, as part of a multimodal analgesic regimen,demonstrated some opioid spar<strong>in</strong>g effect (282).Perioperative regional LA techniques have also beenshown to be effective <strong>and</strong> aga<strong>in</strong> require further evaluation(271,279). Little good evidence exists with regardto the optimum analgesic regimen.Analgesia Table 5.7 Laparoscopic surgeryAgentTechniqueLA* Infiltration 1)LA* Aerosolised 3LA Caudal 1)Opioid Parenteral/oral 3NSAID a 1)Paracetamol a 3a As part of a multimodal technique.DirectevidenceIndirectevidence5.8 Orthopedics, sp<strong>in</strong>al <strong>and</strong> plastic surgery5.8.1 Lower limb surgeryThe surgery covered <strong>in</strong> this section ranges from relativelym<strong>in</strong>or s<strong>in</strong>gle site orthopedic surgery to moremajor procedures such as multiple level osteotomies.The population of patients requir<strong>in</strong>g femoral <strong>and</strong>pelvic osteotomies <strong>in</strong>cludes those suffer<strong>in</strong>g from cerebralpalsy; pa<strong>in</strong> <strong>in</strong> this population can also precipitatepa<strong>in</strong>ful muscle spasm requir<strong>in</strong>g specific managementwith benzodiazep<strong>in</strong>es.Multimodal analgesia is suitable: there is particularlyextensive experience of the use of local anesthetic techniquesfor this type of surgery. Concerns have beenexpressed that NSAIDs may <strong>in</strong>hibit new bone growthfollow<strong>in</strong>g orthopedic surgery; this is addressed below.<strong>Good</strong> practice po<strong>in</strong>tThere is no evidence from studies <strong>in</strong> children thatNSAIDs have a deleterious effect on bone fusion. Theanalgesic benefit of short-term NSAID use has beendemonstrated <strong>and</strong> may frequently outweigh any hypotheticalrisk.48 ª 2012 Blackwell Publish<strong>in</strong>g Ltd, Pediatric Anesthesia, 22 (Suppl. 1), 1–79

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