A Practical Approach, Second Edition=Ronald D. Ho.pdf

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Organ/StructureCervicalcentrumCodeNumberObservation10652 Unossified cervicalarchAtlas = #1, Axis = #210653 Absent cervical Agenesis, Aplastic Atlas = #1, Axis = #2centrum10654 Bipartite ossification of Bifid ossification Atlas = #1, Axis = #2cervical centrum10655 Dumbbell ossification Dumbbell-shaped Atlas = #1, Axis = #2of cervical centrum10656 Dumbbell-shapedAtlas = #1, Axis = #2cartilage of cervicalcentrum10657 Fused cervical centrum Specify structures that arefused Atlas = #1,Axis = #210658 Fused cervical centrumSpecify structures that arecartilagefused Atlas = #1,Axis = #210659 Hemicentric cervicalAtlas = #1, Axis = #2centrum10660 Incomplete ossification Reduced ossification Atlas = #1, Axis = #2of cervical centrum10661 Misaligned cervicalAtlas = #1, Axis = #2centrum10662 Misshapen cervicalcentrumSynonym orRelated TermNon-preferredTerm Definition NoteAbnormally shaped,Atlas = #1, Axis = #2Asymmetric, IrregularlyshapedBifid, Bipartite, Cleft Atlas = #1, Axis = #210663 Split cartilage ofcervical centrum10664 Supernumerary Additional, Extra Atlas = #1, Axis = #2cervical centrum10665 Unilateral cervicalAtlas = #1, Axis = #2centrum cartilage10666 Unossified cervicalAtlas = #1, Axis = #2centrumCervical 10667 Absent cervical Agenesis, AplasticNormal: 7 in rodent andvertebravertebrarabbit10668 Cervical hemivertebra10669 Malpositioned cervical Displaced, Ectopicvertebra10670 Supernumerary Additional, ExtraNormal: 7 in rodent andcervical vertebrarabbitThoracic arch 10671 Absent thoracic arch Agenesis, AplasticTERMINOLOGY OF ANATOMICAL DEFECTS 953© 2006 by Taylor & Francis Group, LLC
Terminology of developmental abnormalities in common laboratory mammals (version 1): Skeletal abnormalities 1 (continued)Region/Organ/StructureThoraciccentrumCodeNumberObservationSynonym orRelated TermNon-preferredTerm Definition Note10672 Fused thoracic arch Specify structures that arefused10673 Incomplete ossification Reduced ossificationof thoracic arch10674 Malpositioned thoracicarch10675 Misaligned thoracicarch10676 Misshapen thoracicarchAbnormally shaped,Asymmetric, Irregularlyshaped10677 Small thoracic arch Hypoplastic, Reduced,Rudimentary10678 Supernumerary Additional, Extrathoracic arch10679 Unossified thoracicarch10680 Absent thoracic Agenesis, Aplasticcentrum10681 Bipartite ossification of Bifid ossificationthoracic centrum10682 Dumbbell ossification Dumbbell-shapedof thoracic centrum10683 Dumbbell-shapedcartilage of thoraciccentrum10684 Fused thoracic centrum Specify structures that arefused10685 Fused thoracic centrumSpecify structures that arecartilagefused10686 Hemicentric thoraciccentrum10687 Incomplete ossification Reduced ossificationof thoracic centrum10688 Misaligned thoraciccentrum954 DEVELOPMENTAL REPRODUCTIVE TOXICOLOGY: A PRACTICAL APPROACH, SECOND EDITION© 2006 by Taylor & Francis Group, LLC
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Second EditionDEVELOPMENTALandREPRO
Page 4 and 5: Published in 2006 byCRC PressTaylor
Page 6 and 7: Chapter 12Chapter 13Chapter 14Chapt
Page 8 and 9: The EditorRonald D. Hood, Ph.D., is
Page 10 and 11: Alan M. HobermanArgus ResearchHorsh
Page 12 and 13: APPENDIX ATerminology of Anatomical
Page 14 and 15: TERMINOLOGY OF ANATOMICAL DEFECTS 9
Page 24 and 25: Organ/StructureCodeNumberObservatio
Page 30 and 31: Organ/Structure10145 Ocular colobom
Page 34 and 35: Organ/StructurePulmonaryarteryPulmo
Page 42 and 43: Terminology of developmental abnorm
Page 56 and 57: Organ/Structure10689 Misshapen thor
Page 58 and 59: Organ/StructureSacralcentrumSacralv
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1004 DEVELOPMENTAL REPRODUCTIVE TOX
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Table 1Human Non-human Primate Rat
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Table 1 (continued)Sertoli CellsHum
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Table 2 (continued) Landmarks in th
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Table 2 (continued) Landmarks in th
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POSTNATAL DEVELOPMENTAL MILESTONES
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PART IPrinciples and Mechanisms© 2
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4 DEVELOPMENTAL REPRODUCTIVE TOXICO
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10 DEVELOPMENTAL REPRODUCTIVE TOXIC
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Table 2.6Receptor(Official Name a )
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Clearly, more research needs to be
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100 DEVELOPMENTAL REPRODUCTIVE TOXI
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CHAPTER 6Comparative Features of Ve
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COMPARATIVE FEATURES OF VERTEBRATE
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Table 6.2Comparative reproductive a
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Maturation andRelease ofGametesSper
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Amniotic cavity 9.5 1.5 1-4 1-4,6,9
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Posteriorcardinal veinsestablishedT
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PosteriorcardinaldegenerationRight
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StomachappearsThirdpharyngealpouch;
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Table 6.6DescriptionComparative ges
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ParathyroidParathyroids 12.5 6.2 41
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Table 6.8DescriptionComparative ges
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Formation ofchoroid plexusof latera
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Optic nervefibers presentDifferenti
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Table 6.10DescriptionMuscular Syste
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Distalphalanges offingersseparatedF
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Table 6.11DescriptionIntermediateme
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Table 6.12DescriptionComparative ge
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CHAPTER 7Developmental Toxicity Tes
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DEVELOPMENTAL TOXICITY TESTING —
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Female 0.00-0.69 0.004-0.39 0.00-0.
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Figure 8.11775Pott DescribesScrotal
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The underlying physiology of juveni
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Table 8.5Total body composition by
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Table 8.6Serum chemistry values for
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Table 8.7Parameter bHematology valu
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CHAPTER 9Significance, Reliability,
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DEVELOPMENTAL AND REPRODUCTIVE TOXI
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Prior to the early 1980s, numerous
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Figure 9.51906Food andDrugs Act2000
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Table 9.18Selected comparison point
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Table 9.33Selected comparison point
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Table 9.48What do regulatorswant to
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CHAPTER 10Testing for Reproductive
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TESTING FOR REPRODUCTIVE TOXICITY 4
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We would like to acknowledge the ef
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CHAPTER 12Role of Xenobiotic Metabo
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ROLE OF XENOBIOTIC METABOLISM IN DE
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y ESR spectrometry. 122 Further ESR
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CHAPTER 13Use of Toxicokinetics in
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USE OF TOXICOKINETICS IN DEVELOPMEN
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CHAPTER 17Statistical Analysis for
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STATISTICAL ANALYSIS FOR DEVELOPMEN
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CHAPTER 19Perspectives on the Devel
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PERSPECTIVES ON THE DEVELOPMENTAL A
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Guideline OECD 415 (One Generation)
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The Office of Prevention, Pesticide
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CHAPTER 20Human Studies — Epidemi
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HUMAN STUDIES 801I. INTRODUCTIONEpi
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HUMAN STUDIES 803is actively trying
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HUMAN STUDIES 805100908070Induced a
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HUMAN STUDIES 811from monstrous, us
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CHAPTER 21Developmental and Reprodu
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There are six factors that may affe
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