A Practical Approach, Second Edition=Ronald D. Ho.pdf

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NONCLINICAL JUVENILE TOXICITY TESTING 325111. Vitarella, D., James, R.A., Miller, K.L., Struve, M.F., Wong, B.A., and Dorman, D.C., Developmentof an inhalation system for the simultaneous exposure of rat dams and pups during developmentalneurotoxicity studies, Inhalation Toxicol., 10, 1095, 1998.112. Barr, G.A. and Lithgow, T., Effect of age on benzodiazepine-induced behavioural convulsions in rats,Nature, 302, 431, 1983.113. Sheets, L.P., A consideration of age-dependent differences in susceptibility to organophosphorous andpyrethroid insecticides, Neurotoxicology, 21, 57, 2000.114. Cantalamessa, F., Acute toxicity of two pyrethroids, permethrin, and cypermethrin in neonatal andadult rats, Arch. Toxicol., 67, 510, 1993.115. Kallman, M.J., Assessment of motoric effects, in Developmental Neurotoxicology, Harry, G.J., Ed.,CRC Press, Boca Raton, 1994, pp. 103–122.116. Shafer, T.J., Meyer, D.A., and Crofton, K.M., Developmental neurotoxicity of pyrethroid insecticides:critical review and future research needs, Environ. Health Perspect. (in press, accessed October 29,2004 at http://ehp.niehs.nih.gov/members/2004/7254/7254.pdf).117. Schaefer, G.J., Nemec, M.D., Herberth, M.T., Pitt, J.A., Radovsky, A.E., and Knapp, J.F., Validationof developmental neurotoxicity endpoints in rats administered methimazole in drinking water[Abstract], The Toxicologist, 66, 234, 2002.118. Ruppert, P.H., Dean, K.F., and Reiter, L.W., Comparative developmental toxicity of triethyltin usingsplit-litter and whole-litter dosing, J. Toxicol. Environ. Health, 12, 73, 1983.119. Pearson, D.E., Teicher, M.H., Shaywitz, B.A., Cohen, D.J., Young, J.G., and Anderson, G.M., Environmentalinfluences on body weight and behavior in developing rats after neonatal 6-hydroxydopamine,Science, 209, 715, 1980.120. Pizzi, W.J., Rode, E.C., and Barnhart, J.E., Differential effects of methylphenidate on the growth ofneonatal and adolescent rats, Neurotoxicol. Teratol., 9, 107, 1987.121. Pizzi, W.J., Rode, E.C., and Barnhart, J.E., Methylphenidate and growth: demonstration of a growthimpairment and a growth-rebound phenomenon, Dev. Pharmacol. Ther., 9, 361, 1986.122. Greely, G.H. and Kizer, J.S., The effects of chronic methylphenidate treatment on growth and endocrinefunction in the developing rat, J. Pharmacol. Exp. Ther., 215, 545, 1980.123. Zoetis, T., Tassinari, M.S., Bagi, C., Walthall, K., and Hurtt, M.E., Species comparison of postnatalbone growth and development, Birth Defects Res. Part B Dev. Reprod. Toxicol., 68, 86, 2003.124. Padgett, E.L., Chengelis, C.P., Rhodes, K.K., Holbrook, D.L., Haas, M.C., Lehman, J.L., Bell, C.R.,and Nemec, M.D., Postpartum developmental reference data from beagle dogs over four definedpediatric stages, The Toxicologist, 66, 236, 2002.125. Roy, A.K., Schiop, M.J., and Dowbenko, D.J., Regulation of the hepatic synthesis of alpha-2 urinaryglobulin and its corresponding messenger RNA in maturing male rats, FEBS Letters, 70, 137, 1976.126. Neuhaus, O.W. and Flory, W., Age-dependent changes in the excretion of urinary proteins by the rat,Nephron., 22, 570, 1978.127. Gopinath, C., Prentice, D.E. and Lewis, D.J., Atlas of Experimental Toxicological Pathology, KluwerAcademic Publishers, Boston, 1987, p. 78.128. Gomez R.A., Sequeira Lopez, M.L., Fernandez, L., Chernavvksy, D.R., and Norwood, V.F., Thematuring kidney: development and susceptibility, Ren. Fail., 21, 283, 1999.129. Organization for Economic Cooperation and Development (OECD), Guideline for the testing ofchemicals, Developmental Neurotoxicity Study, Proposal for a New Guideline 426, September 2003(Draft).130. Lochry, E.A., Concurrent use of behavioral/functional testing in existing reproductive and developmentaltoxicity screens, J. Am. Coll. Toxicol., 6, 433, 1987.131. ICH Expert Working Group, ICH Harmonised Tripartite Guideline, Detection of Toxicity to Reproductionfor Medicinal Products, S5A, International Conference on Harmonisation of TechnicalRequirements for Registration of Pharmaceuticals for Human Use (ICH), Geneva, Switzerland, FinalizedJune 1993.132. Adams, J., Methods in behavioral teratology, in Handbook of Behavioral Teratology, Riley, E.P. andVorhees, C.V., Eds, Plenum Press, New York, 1986, p. 67.133. Altman, J. and Sudarshan, K., Postnatal development of locomotion in the laboratory rat, Anim. Behav.,23, 896, 1975.© 2006 by Taylor & Francis Group, LLC
326 DEVELOPMENTAL REPRODUCTIVE TOXICOLOGY: A PRACTICAL APPROACH, SECOND EDITION134. Rinaldi, P.C. and Thompson, R.R., Age, sex and strain comparison of habituation of the startle responsein the rat, Physiol. Behav., 35, 9, 1985.135. Glass, D.C. and Singer, J.E., Urban Stress: Experiments on Noise and Social Stressors, AcademicPress, New York, 1972, p. 10.136. Thompson, R.F. and Spencer, W.A., Habituation: a model phenomenon for the study of neuronalsubstrates of behavior, Psychol. Rev., 73, 16, 1966.137. Clark, R.L., Endpoints of reproductive system development, in An Evaluation and Interpretation ofReproductive Endpoints for Human Health Risk Assessment, Daston, G. and Kimmel, C.A., Eds.,ILSI Press, Washington DC, 1998, 10.138. Korenbrot, C.C., Huhtaniemi, I.T., and Weiner, R.I., Preputial separation as an external sign of pubertaldevelopment in the male rat, Biol. Reprod., 17, 298, 1977.139. Cameron, J.L., Metabolic cues for the onset of puberty, Horm. Res., 36, 97, 1991.140. Ashby, J. and Lefevre, P.A., The peripubertal male rat assay as an alternative to the Hershbergercastrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators, J.Appl. Toxicol., 20, 35, 2000.141. Kelce, W.R., Stone, C.R., Laws, S.C., Gray, L.E., Kemppainen, J.A., and Wilson, E.M., PersistentDDT metabolite p,p’-DDE is a potent androgen receptor antagonist, Nature, 375, 581, 1995.142. Hossain, M., Devi, P.U., and Bisht, K.S., Effect of prenatal gamma irradiation during the late fetalperiod on the postnatal development of the mouse, Teratology, 59, 133, 1999.143. Devi, P.U. and Hossain, M., Effect of early fetal irradiation on the postnatal development of mouse,Teratology, 64, 45, 2001.144. Torrente, M., Colomina, M.T., and Domingo, J.L., Effects of prenatal exposure to manganese onpostnatal development and behavior in mice: influence of maternal restraint, Neurotoxicol. Teratol.,24, 219, 2002.145. Adams, J., Buelke-Sam, J., Kimmel, C.A., Nelson, C.J., Reiter, L.W., Sobotka, T.J., Tilson, H.A., andNelson, B.K., Collaborative behavioral teratology study: protocol design and testing procedures,Neurobehav. Toxicol. Teratol., 7, 579, 1985.146. Gray, L.E. Jr. and Ostby, J.S., In utero 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters reproductivemorphology and function in female rat offspring, Toxicol. Appl. Pharmacol., 133, 285, 1995.147. Kim, H.S., Shin, J.H., Moon, H.J., Kang, I.H., Kim, T.S., Kim, I.Y., Seok, J.H., Pyo, M.Y., and Han,S.Y., Comparative estrogenic effects of p-nonylphenol by 3-day uterotrophic assay and female pubertalonset assay, Reprod. Toxicol., 16, 259, 2002.148. Wood, S.L., Beyer, B.K., and Cappon, G.D., Species comparison of postnatal CNS development:functional measures, Birth Defects Res. Part B Dev. Reprod. Toxicol., 68, 391, 2003.149. Campbell, B.A., Lytle, L.D., and Fibiger, H.C., Ontogeny of adrenergic arousal and cholinergicinhibitory mechanisms in the rat, Science, 166, 635, 1969150. Buelke-Sam, J., Kimmel, G.L., Webb, P.J., Slikker, W. Jr., Newport, G.D., Nelson, C.J., and Kimmel,C.A., Postnatal toxicity following prenatal reserpine exposure in rats: effects of dose and dosingschedule, Fundam. Appl. Toxicol., 4, 983, 1984.151. Buelke-Sam, J., Ali, S.F., Kimmel, G.L., Slikker, W. Jr., Newport, G.D., and Harmon, J.R., Postnatalfunction following prenatal reserpine exposure in rats: neurobehavioral toxicity, Neurotoxicol. Teratol.,11, 515, 1989.152. Hoffman, H.S. and Fleshler, M., Startle reaction: modification by background acoustic stimulation,Science, 141, 928, 1963.153. Ison, J.R. and Hammond, G.R., Modification of the startle reflex in the rat by changes in the auditoryand visual environments, J. Comp. Physiol. Psychol., 75, 435, 1971.154. Vorhees, C.V., Acuff-Smith, K.D., Schilling, M.A., Fisher, J.E., Moran, M.S., and Buelke-Sam, J., Adevelopmental neurotoxicity evaluation of the effects of prenatal exposure to fluoxetine in rats,Fundam.. Appl. Toxicol., 23, 194, 1994.155. Biel, W.C., Early age differences in maze performance in the albino rat, J. Gen. Psych., 56, 439, 1940.156. Vorhees, C.V., Butcher, R.E., Brunner, R.L., and Sobotka, T.J., A developmental test battery forneurobehavioral toxicity in rats: a preliminary analysis using monosodium glutamate, calcium carrageenanand hydroxyurea, Toxicol. Appl. Pharmacol., 50, 267, 1979.157. Morris, R.G.M., Spatial localization does not require the presence of local cues, Learn. Motivat., 12,239, 1981.© 2006 by Taylor & Francis Group, LLC
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Second EditionDEVELOPMENTALandREPRO
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Published in 2006 byCRC PressTaylor
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Chapter 12Chapter 13Chapter 14Chapt
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The EditorRonald D. Hood, Ph.D., is
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Alan M. HobermanArgus ResearchHorsh
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APPENDIX ATerminology of Anatomical
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TERMINOLOGY OF ANATOMICAL DEFECTS 9
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Organ/StructureCodeNumberObservatio
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Organ/Structure10145 Ocular colobom
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Organ/StructurePulmonaryarteryPulmo
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Terminology of developmental abnorm
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Organ/StructureCervicalcentrumCodeN
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Organ/Structure10689 Misshapen thor
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968 DEVELOPMENTAL REPRODUCTIVE TOXI
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1000 DEVELOPMENTAL REPRODUCTIVE TOX
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Table 1Human Non-human Primate Rat
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Table 1 (continued)Sertoli CellsHum
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Table 2 (continued) Landmarks in th
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POSTNATAL DEVELOPMENTAL MILESTONES
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PART IPrinciples and Mechanisms© 2
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4 DEVELOPMENTAL REPRODUCTIVE TOXICO
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10 DEVELOPMENTAL REPRODUCTIVE TOXIC
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Table 2.6Receptor(Official Name a )
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Clearly, more research needs to be
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CHAPTER 6Comparative Features of Ve
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COMPARATIVE FEATURES OF VERTEBRATE
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Table 6.2Comparative reproductive a
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Maturation andRelease ofGametesSper
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Amniotic cavity 9.5 1.5 1-4 1-4,6,9
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Posteriorcardinal veinsestablishedT
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PosteriorcardinaldegenerationRight
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Table 6.6DescriptionComparative ges
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ParathyroidParathyroids 12.5 6.2 41
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Table 6.8DescriptionComparative ges
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Formation ofchoroid plexusof latera
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Table 6.10DescriptionMuscular Syste
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CHAPTER 7Developmental Toxicity Tes
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DEVELOPMENTAL TOXICITY TESTING —
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Figure 8.11775Pott DescribesScrotal
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DEVELOPMENTAL AND REPRODUCTIVE TOXI
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Table 9.33Selected comparison point
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Table 9.48What do regulatorswant to
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CHAPTER 10Testing for Reproductive
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TESTING FOR REPRODUCTIVE TOXICITY 4
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CHAPTER 12Role of Xenobiotic Metabo
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ROLE OF XENOBIOTIC METABOLISM IN DE
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CHAPTER 13Use of Toxicokinetics in
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CHAPTER 17Statistical Analysis for
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STATISTICAL ANALYSIS FOR DEVELOPMEN
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CHAPTER 19Perspectives on the Devel
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PERSPECTIVES ON THE DEVELOPMENTAL A
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Guideline OECD 415 (One Generation)
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The Office of Prevention, Pesticide
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CHAPTER 20Human Studies — Epidemi
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HUMAN STUDIES 801I. INTRODUCTIONEpi
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HUMAN STUDIES 803is actively trying
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HUMAN STUDIES 805100908070Induced a
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CHAPTER 21Developmental and Reprodu
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A Practical Approach, Second Edition=Ronald D. Ho.pdf

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