A Practical Approach, Second Edition=Ronald D. Ho.pdf

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Organ/StructureSacralcentrumSacralvertebraCodeNumberObservationSynonym orRelated Term10730 Misshapen sacral arch Abnormally shaped,Asymmetric, Irregularlyshaped10731 Small sacral arch Hypoplastic, Reduced,Rudimentary10732 Supernumerary sacral Additional, Extraarch10733 Unossified sacral arch10734 Absent sacral centrum Agenesis, AplasticNon-preferredTerm Definition Note10735 Bipartite ossification of Bifid ossificationsacral centrum10736 Dumbbell ossification Dumbbell-shapedof sacral centrum10737 Dumbbell-shapedcartilage of sacralcentrum10738 Fused sacral centrum Specify structures that arefused10739 Fused sacral centrumcartilageSpecify structures that arefused10740 Hemicentric sacralcentrum10741 Incomplete ossification Reduced ossificationof sacral centrum10742 Misaligned sacralcentrum10743 Misshapen sacralcentrumAbnormally shaped,Asymmetric, Irregularlyshaped10744 Split cartilage of sacral Bifid, Bipartite, Cleftcentrum10745 Supernumerary sacral Additional, Extracentrum10746 Unilateral sacralcentrum cartilage10747 Unossified sacralcentrum10748 Absent sacral vertebra Agenesis, Aplastic Normal: 4 in rodent andrabbit10749 Malpositioned sacral Displaced, EctopicvertebraTERMINOLOGY OF ANATOMICAL DEFECTS 957© 2006 by Taylor & Francis Group, LLC
Terminology of developmental abnormalities in common laboratory mammals (version 1): Skeletal abnormalities 1 (continued)Region/Organ/StructureCodeNumberObservation10750 Sacral hemivertebra10751 Supernumerary sacralvertebraAdditional, ExtraNormal: 4 in rodent andrabbitCaudal arch 10752 Absent caudal arch Agenesis, Aplastic10753 Fused caudal arch Specify structures that arefused10754 Incomplete ossification Reduced ossificationof caudal arch10755 Malpositioned caudal Displaced, Ectopicarch10756 Misaligned caudal arch10757 Misshapen caudal arch Abnormally shaped,Asymmetric, Irregularlyshaped10758 Small caudal arch Hypoplastic, Reduced,Rudimentary10759 Unossified caudal archCaudal10760 Absent caudal centrum Agenesis, Aplasticcentrum10761 Bipartite ossification of Bifid ossificationcaudal centrum10762 Dumbbell ossification Dumbbell-shapedof caudal centrum10763 Fused caudal centrum Specify structures that arefused10764 Hemicentric caudalcentrum10765 Incomplete ossificationof caudal centrumReduced ossification10766 Misaligned caudalcentrum10767 Misshapen caudalcentrum10768 Unossified caudalcentrumSynonym orRelated TermAbnormally shaped,Asymmetric, IrregularlyshapedNon-preferredTerm Definition Note958 DEVELOPMENTAL REPRODUCTIVE TOXICOLOGY: A PRACTICAL APPROACH, SECOND EDITION© 2006 by Taylor & Francis Group, LLC
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Second EditionDEVELOPMENTALandREPRO
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Published in 2006 byCRC PressTaylor
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Chapter 12Chapter 13Chapter 14Chapt
Page 8 and 9: The EditorRonald D. Hood, Ph.D., is
Page 10 and 11: Alan M. HobermanArgus ResearchHorsh
Page 12 and 13: APPENDIX ATerminology of Anatomical
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1008 DEVELOPMENTAL REPRODUCTIVE TOX
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Table 1Human Non-human Primate Rat
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Table 1 (continued)Sertoli CellsHum
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Table 2 (continued) Landmarks in th
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Table 2 (continued) Landmarks in th
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POSTNATAL DEVELOPMENTAL MILESTONES
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PART IPrinciples and Mechanisms© 2
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4 DEVELOPMENTAL REPRODUCTIVE TOXICO
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10 DEVELOPMENTAL REPRODUCTIVE TOXIC
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Table 2.6Receptor(Official Name a )
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Clearly, more research needs to be
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100 DEVELOPMENTAL REPRODUCTIVE TOXI
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CHAPTER 6Comparative Features of Ve
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COMPARATIVE FEATURES OF VERTEBRATE
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Table 6.2Comparative reproductive a
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Maturation andRelease ofGametesSper
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Amniotic cavity 9.5 1.5 1-4 1-4,6,9
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Posteriorcardinal veinsestablishedT
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PosteriorcardinaldegenerationRight
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StomachappearsThirdpharyngealpouch;
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Table 6.6DescriptionComparative ges
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ParathyroidParathyroids 12.5 6.2 41
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Table 6.8DescriptionComparative ges
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Formation ofchoroid plexusof latera
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Optic nervefibers presentDifferenti
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Table 6.10DescriptionMuscular Syste
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Distalphalanges offingersseparatedF
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Table 6.11DescriptionIntermediateme
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Table 6.12DescriptionComparative ge
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CHAPTER 7Developmental Toxicity Tes
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DEVELOPMENTAL TOXICITY TESTING —
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Female 0.00-0.69 0.004-0.39 0.00-0.
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Figure 8.11775Pott DescribesScrotal
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The underlying physiology of juveni
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Table 8.5Total body composition by
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Table 8.6Serum chemistry values for
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Table 8.7Parameter bHematology valu
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CHAPTER 9Significance, Reliability,
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DEVELOPMENTAL AND REPRODUCTIVE TOXI
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Prior to the early 1980s, numerous
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Figure 9.51906Food andDrugs Act2000
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Table 9.18Selected comparison point
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Table 9.33Selected comparison point
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Table 9.48What do regulatorswant to
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CHAPTER 10Testing for Reproductive
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TESTING FOR REPRODUCTIVE TOXICITY 4
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We would like to acknowledge the ef
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CHAPTER 12Role of Xenobiotic Metabo
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y ESR spectrometry. 122 Further ESR
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CHAPTER 13Use of Toxicokinetics in
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USE OF TOXICOKINETICS IN DEVELOPMEN
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CHAPTER 17Statistical Analysis for
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STATISTICAL ANALYSIS FOR DEVELOPMEN
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CHAPTER 19Perspectives on the Devel
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PERSPECTIVES ON THE DEVELOPMENTAL A
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Guideline OECD 415 (One Generation)
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The Office of Prevention, Pesticide
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CHAPTER 20Human Studies — Epidemi
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HUMAN STUDIES 801I. INTRODUCTIONEpi
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HUMAN STUDIES 803is actively trying
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HUMAN STUDIES 811from monstrous, us
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CHAPTER 21Developmental and Reprodu
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There are six factors that may affe
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