Advisory Committee on Pesticides Annual Report 2001

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Appendix VI constitutional factors (genetic susceptibility, hormonal status) may also contribute to effects Carcinoma Clastogen malignant tumour arising from epithelial cells lining, for example, the alimentary, respiratory and urogenital tracts and from epidermis, also from solid viscera such as the liver, pancreas, kidneys and some endocrine glands an agent that produces chromosome breaks and other structural aberrations such as translocations (q.v.). Clastogens may be viruses or physical agents as well as chemicals. Clastogenic events play an important part in the development of some tumours COPR Control of Pesticides Regulations 1986 DETR DNA DT 50 EC ECCO EMDI FAO Department of the Environment, Transport and the Regions deoxyribonucleic acid. The carrier of genetic information for most organisms time taken to degrade by 50 percent European Community EC Co-ordination (EU expert peer review groups) estimated maximum daily intake Food and Agriculture Organisation 105 FEPA Food and Environment Protection Act 1985 GAP GATT GIFAP GLP ha Half life good agricultural practice General Agreement on Tariffs and Trade Groupement International des Associations Nationales de Fabricants de Produits Agrochimiques (the European trade association for the agrochemical industry) Good Laboratory Practice hectare time interval required for half of a quantity of material to be eliminated naturally
<strong>Advisory</strong> <strong>Committee</strong> on Pesticides Annual Report 2001 Heinz bodies roughly spherical inclusion bodies in red blood cells resulting from precipitation of haemoglobin 106 HSE IDS IPM In vitro In vivo JMPR Koc LOAEL LC 50 LD 50 MAC MAFF Health and Safety Executive Inter-Departmental Secretariat, a sub-committee of the ACP integrated pest management term used to describe effects in biological material outside the living animal term used to describe effects in living animals Joint FAO/WHO meeting on pesticide residues organic carbon adsorption coefficient lowest observable adverse effect level. The lowest administered dose at which an effect has been observed the theoretical lethal concentration for 50 percent of a group of animals the theoretical lethal dose for 50 percent of a group of animals maximum allowable concentration Ministry of Agriculture, Fisheries and Food (UK) µg microgram MRL n NAEL NEL NOAEL NOAEC NOEC NOEL OECD OPIDN Maximum Residue Limit normal (defining isomeric configuration) no adverse effect level no effect level no observed adverse effect level no observed adverse effect concentration no observed effect concentration no observed effect level Organisation for Economic Co-operation and Development organophosphate-induced delayed neuropathy
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Advisory Committee on Pesticides Annual Report 2001

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