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Advisory Committee on Pesticides Annual Report 2001

ACP Annual Report 2001 - Pesticides Safety Directorate

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<str<strong>on</strong>g>Advisory</str<strong>on</strong>g> <str<strong>on</strong>g>Committee</str<strong>on</strong>g> <strong>on</strong> <strong>Pesticides</strong> <strong>Annual</strong> <strong>Report</strong> <strong>2001</strong><br />

for incomplete oral absorpti<strong>on</strong>) were applied to the NOAEL of 4.89 mg/kg<br />

bw/day. This resulted in a systemic short-term AOEL of 0.02 mg/kg bw/day.<br />

The informati<strong>on</strong> submitted <strong>on</strong> operator exposure was c<strong>on</strong>sidered sufficient to<br />

support approval of ‘C<strong>on</strong>serve’ for use <strong>on</strong> ornamental crops. No further data<br />

were required. However, use of protective gloves and coveralls when handling<br />

the product and during applicati<strong>on</strong> when applying by hand-held equipment or<br />

handling c<strong>on</strong>taminated surfaces was recommended. Modelling of operator<br />

exposure with this level of pers<strong>on</strong>al protective equipment (PPE) predicted<br />

exposures at or below the AOEL.<br />

The evaluati<strong>on</strong> indicated that recommended uses of ‘C<strong>on</strong>serve’ might result in<br />

exposure of bystanders, but this was acceptable, as the extent of exposure<br />

was likely to be significantly less than the AOEL. With respect to worker<br />

exposure, the estimated systemic exposure from the use of ‘C<strong>on</strong>serve’ under<br />

cover (glass or plastic) was less than the AOEL. Therefore, worker exposure<br />

was also judged acceptable, with no requirement for PPE or a re-entry interval.<br />

26<br />

Given the proposed use, it was c<strong>on</strong>sidered that envir<strong>on</strong>mental c<strong>on</strong>taminati<strong>on</strong><br />

(i.e. to soil, surface water and groundwater) by the active substance and its<br />

metabolites from direct use was likely to be limited. The incorporati<strong>on</strong> of<br />

spinosad-c<strong>on</strong>taminated compost (as waste from ornamental plant producti<strong>on</strong>)<br />

into field soils was c<strong>on</strong>sidered to pose a low risk with respect to terrestrial<br />

organisms, rotati<strong>on</strong>al field crops and c<strong>on</strong>taminati<strong>on</strong> of surface and ground water.<br />

The proposed use <strong>on</strong> protected ornamentals would result in limited exposure<br />

of wildlife. Spinosad is highly toxic to bees and certain n<strong>on</strong>-target arthropod<br />

species. Neither of these groups of organisms would be directly exposed at<br />

the time of applicati<strong>on</strong>. However, bees and other n<strong>on</strong>-target arthropods might<br />

be attracted to certain types of treated ornamentals subsequently moved to<br />

outside locati<strong>on</strong>s. Therefore, the risk to bees from residues of spinosad was<br />

assessed. It was c<strong>on</strong>sidered, <strong>on</strong> the basis of field studies, to be acceptable.<br />

Studies <strong>on</strong> the residual toxicity of spinosad to a range arthropod species used<br />

in Integrated Pest Management (IPM) systems indicated that toxicity of the<br />

compound declines with age. These studies provided reassurance that<br />

significant impacts <strong>on</strong> natural populati<strong>on</strong>s of n<strong>on</strong>-target arthropods would<br />

be unlikely.<br />

Spinosad is of moderate toxicity to certain groups of aquatic life (i.e. Daphnia<br />

magna and Chir<strong>on</strong>omus riparius). Therefore, the product was classified as<br />

‘Harmful to fish and other aquatic life’. Potential c<strong>on</strong>taminati<strong>on</strong> of surface<br />

water via spray drift and drainage was c<strong>on</strong>sidered to be minimal from the

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