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Advisory Committee on Pesticides Annual Report 2001

ACP Annual Report 2001 - Pesticides Safety Directorate

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<str<strong>on</strong>g>Advisory</str<strong>on</strong>g> <str<strong>on</strong>g>Committee</str<strong>on</strong>g> <strong>on</strong> <strong>Pesticides</strong> <strong>Annual</strong> <strong>Report</strong> <strong>2001</strong><br />

sub chr<strong>on</strong>ic neurotoxicity study was c<strong>on</strong>sidered more appropriate than the<br />

method proposed. The absence of dermal studies was also noted.<br />

Azafenidin<br />

Azafenidin is a selective triazol<strong>on</strong>e herbicide new to the EU. It affects sensitive<br />

weeds through inhibiti<strong>on</strong> of protoporphyrinogen oxidase involved in the<br />

protoporphyrin biosynthesis pathway.<br />

The EU applicati<strong>on</strong> had been evaluated by Spain, the Rapporteur Member<br />

State (RMS), and a Draft Assessment <strong>Report</strong> (DAR) prepared. The DAR<br />

c<strong>on</strong>sidered the use of a water dispersible granule formulati<strong>on</strong> c<strong>on</strong>taining<br />

800g/kg azafenidin, to be used in grape vineyards, citrus and olive orchards<br />

to c<strong>on</strong>trol broad-leaved weeds. No applicati<strong>on</strong>s for use in the UK had<br />

been made.<br />

32<br />

The DAR had been distributed to all Member States for c<strong>on</strong>siderati<strong>on</strong> in the<br />

EU peer review process. The RMS proposed a postp<strong>on</strong>ement of a decisi<strong>on</strong><br />

<strong>on</strong> inclusi<strong>on</strong> of azafenidin in Annex I of Directive 91/414/EEC until evaluati<strong>on</strong><br />

of certain further data.<br />

ACP members provided written comments <strong>on</strong> the assessment that generally<br />

agreed with the report but questi<strong>on</strong>ed some aspects of the toxicology<br />

assessment.<br />

Benzoic acid<br />

Benzoic acid is a c<strong>on</strong>tact disinfectant. Its proposed uses in horticulture<br />

(floriculture) were regarded as within the remit of EU Directive 91/414/EEC<br />

for c<strong>on</strong>siderati<strong>on</strong> as a new pesticide active substance.<br />

The EU applicati<strong>on</strong> had been evaluated by Germany, the Rapporteur Member<br />

State (RMS), and a Draft Assessment <strong>Report</strong> (DAR) prepared. The DAR<br />

assessed a soluble liquid (SL) formulati<strong>on</strong> c<strong>on</strong>taining 90 g/l benzoic acid<br />

used for the c<strong>on</strong>trol of fungi, bacteria, viruses and viroids by disinfecti<strong>on</strong><br />

of surfaces, culture vessels and equipment by watering, dipping and soaking<br />

in glasshouses and similar protected cultivati<strong>on</strong> areas. There had been no<br />

applicati<strong>on</strong>s for UK use. The DAR had been distributed to all Member States<br />

for c<strong>on</strong>siderati<strong>on</strong> in the EU peer review process.<br />

The ACP c<strong>on</strong>sidered the DAR and draft comments prepared by PSD. The<br />

<str<strong>on</strong>g>Committee</str<strong>on</strong>g> noted that benzoic acid was an approved food additive and agreed<br />

with the proposed ADI and AOEL and, as no effects were seen in acute<br />

studies, that an ARfD was not needed. Members noted that the in vitro

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