Internal-Medicine
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Questions: 3–13 121<br />
9. A 52-year-old man presents with abdominal<br />
pain and weight loss. He describes a dull<br />
“gnawing” pain located in the epigastric region<br />
radiating to the back. The abdominal examination<br />
is normal with no hepatosplenomegaly or<br />
masses palpated. A computerized tomography<br />
(CT) scan of the abdomen reveals a 3-cm mass<br />
in the pancreas. Which of the following statements<br />
regarding cancer of the pancreas is true?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
tumors of the pancreas are divided<br />
almost equally between those arising<br />
from the exocrine portion and those<br />
arising from the endocrine portion<br />
most endocrine tumors of the pancreas<br />
are malignant<br />
the body of the pancreas is the most<br />
common site of malignancy<br />
adenocarcinoma is the most common<br />
pancreatic cancer<br />
extension is through local invasion;<br />
metastases are a late manifestation<br />
10. A 73-year-old man was born in Taiwan and came<br />
to the United States 3 years ago. He is known to<br />
be HBsAg positive. Which of the following findings<br />
suggests the development of HCC?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
hepatomegaly<br />
hepatic bruits<br />
ascites<br />
jaundice<br />
all of the above<br />
11. A 47-year-old man presents with dark black<br />
stools and vague crampy abdominal pain. On<br />
examination he is pale, blood pressure 100/70<br />
mm Hg, pulse 110/min, and the abdomen is<br />
soft and nontender. Rectal examination confirms<br />
melena, and the patient is transfused<br />
2 units of packed red blood cells. Upper<br />
endoscopy does not identify the source of<br />
bleeding, so a small bowel barium study is<br />
ordered. It reveals a small bowel tumor. Which<br />
of the following statements concerning small<br />
bowel tumors is correct?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
carcinoid is a common cause of small<br />
bowel tumors<br />
malignant adenocarcinoma most<br />
frequently occurs in the duodenum<br />
malignant tumors bleed more frequently<br />
than benign tumors<br />
Peutz-Jeghers syndrome is characterized<br />
only by benign hamartoma<br />
most primary gastrointestinal (GI)<br />
lymphomas are located in the ileum<br />
12. A 58-year-old man is newly diagnosed with<br />
colon cancer and undergoes surgical resection<br />
of the tumor. The pathology result reports no<br />
lymph node involvement, the lesion is 4 cm in<br />
size and involves the muscularis layer. His preoperative<br />
evaluation for distal metastases was<br />
negative. Which of the following factors is most<br />
important in predicting prognosis and survival<br />
in patients with colon cancer?<br />
(A) age under 40<br />
(B) male gender<br />
(C) rectal bleeding<br />
(D) small tumor size<br />
(E) depth of tumor penetration<br />
13. A 64-year-old woman presents with abnormal<br />
vaginal discharge and postmenopausal bleeding.<br />
Pelvic examination reveals a bulky uterus<br />
and no adnexal masses. She undergoes a dilation<br />
and curettage (D&C), and the pathology is<br />
positive for adenocarcinoma. Which of the following<br />
is correct about carcinoma of the uterine<br />
endometrium?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
not associated with diabetes mellitus<br />
and obesity<br />
most common in postmenopausal<br />
woman<br />
associated with multiparity<br />
common in Jews and Muslims<br />
associated with herpes simplex virus<br />
type 2 (HSV-2) infection