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Internal-Medicine

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Questions: 3–13 121<br />

9. A 52-year-old man presents with abdominal<br />

pain and weight loss. He describes a dull<br />

“gnawing” pain located in the epigastric region<br />

radiating to the back. The abdominal examination<br />

is normal with no hepatosplenomegaly or<br />

masses palpated. A computerized tomography<br />

(CT) scan of the abdomen reveals a 3-cm mass<br />

in the pancreas. Which of the following statements<br />

regarding cancer of the pancreas is true?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

tumors of the pancreas are divided<br />

almost equally between those arising<br />

from the exocrine portion and those<br />

arising from the endocrine portion<br />

most endocrine tumors of the pancreas<br />

are malignant<br />

the body of the pancreas is the most<br />

common site of malignancy<br />

adenocarcinoma is the most common<br />

pancreatic cancer<br />

extension is through local invasion;<br />

metastases are a late manifestation<br />

10. A 73-year-old man was born in Taiwan and came<br />

to the United States 3 years ago. He is known to<br />

be HBsAg positive. Which of the following findings<br />

suggests the development of HCC?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

hepatomegaly<br />

hepatic bruits<br />

ascites<br />

jaundice<br />

all of the above<br />

11. A 47-year-old man presents with dark black<br />

stools and vague crampy abdominal pain. On<br />

examination he is pale, blood pressure 100/70<br />

mm Hg, pulse 110/min, and the abdomen is<br />

soft and nontender. Rectal examination confirms<br />

melena, and the patient is transfused<br />

2 units of packed red blood cells. Upper<br />

endoscopy does not identify the source of<br />

bleeding, so a small bowel barium study is<br />

ordered. It reveals a small bowel tumor. Which<br />

of the following statements concerning small<br />

bowel tumors is correct?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

carcinoid is a common cause of small<br />

bowel tumors<br />

malignant adenocarcinoma most<br />

frequently occurs in the duodenum<br />

malignant tumors bleed more frequently<br />

than benign tumors<br />

Peutz-Jeghers syndrome is characterized<br />

only by benign hamartoma<br />

most primary gastrointestinal (GI)<br />

lymphomas are located in the ileum<br />

12. A 58-year-old man is newly diagnosed with<br />

colon cancer and undergoes surgical resection<br />

of the tumor. The pathology result reports no<br />

lymph node involvement, the lesion is 4 cm in<br />

size and involves the muscularis layer. His preoperative<br />

evaluation for distal metastases was<br />

negative. Which of the following factors is most<br />

important in predicting prognosis and survival<br />

in patients with colon cancer?<br />

(A) age under 40<br />

(B) male gender<br />

(C) rectal bleeding<br />

(D) small tumor size<br />

(E) depth of tumor penetration<br />

13. A 64-year-old woman presents with abnormal<br />

vaginal discharge and postmenopausal bleeding.<br />

Pelvic examination reveals a bulky uterus<br />

and no adnexal masses. She undergoes a dilation<br />

and curettage (D&C), and the pathology is<br />

positive for adenocarcinoma. Which of the following<br />

is correct about carcinoma of the uterine<br />

endometrium?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

not associated with diabetes mellitus<br />

and obesity<br />

most common in postmenopausal<br />

woman<br />

associated with multiparity<br />

common in Jews and Muslims<br />

associated with herpes simplex virus<br />

type 2 (HSV-2) infection

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