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Internal-Medicine

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282 14: Comprehensive Review<br />

53. A 25-year-old woman presents with symptoms<br />

of fatigue and weakness. On examination, there<br />

is diplopia, ptosis, weakness, and fatigability of<br />

muscles on repeated use. Which of the following<br />

is the most likely diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

myasthenia gravis<br />

multiple sclerosis<br />

TIAs<br />

muscular dystrophy<br />

cerebral palsy<br />

54. Which of the following women have the highest<br />

risk of developing breast cancer?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

cousins of breast cancer patients<br />

those receiving CXRs as children<br />

those with late-onset menarche<br />

multiparous<br />

those who have already had one breast<br />

cancer<br />

55. A 16-year-old man is newly diagnosed with<br />

cystic fibrosis (CF). Which of the following is<br />

correct for patients with CF diagnosed as an<br />

adult?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

the reproductive system is not involved<br />

heatstroke occurs<br />

pulmonary hypertension is avoided<br />

GI disease is mild<br />

hypersplenism is prominent<br />

56. A 25-year-old nonsmoking man has a 2-cm solitary<br />

pulmonary nodule in the left lower lobe,<br />

with a “popcorn ball” calcification pattern.<br />

Which of following is the most appropriate<br />

next step in management?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

left lower lobe resection<br />

serial CXRs<br />

needle aspiration biopsy<br />

left pneumonectomy<br />

mediastinoscopy<br />

57. A 60-year-old man with unstable angina pectoris<br />

fails to respond to heparin, nitroglycerin,<br />

and beta-adrenergic blockers. He continues to<br />

have ongoing chest pain symptoms. Which of<br />

the following is the most appropriate next step<br />

in management?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

IV streptokinase<br />

coronary angiography<br />

exercise testing<br />

oral aspirin<br />

antihypertensive therapy<br />

58. Which of the following is the major effect of<br />

glucocorticoids in asthma?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

anti-inflammatory<br />

bronchodilatory<br />

sedative<br />

mucus dissolving<br />

antibacterial<br />

59. A 56-year-old man with nephrotic syndrome<br />

undergoes a renal biopsy for diagnosis. The<br />

renal lesion is consistent with a diagnosis of<br />

focal and segmental glomerulosclerosis (FSGS).<br />

Which of the following changes are most likely<br />

to be seen on immunofluorescence studies of<br />

the renal biopsy in FSGS?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

nodular deposits of immunoglobulin M<br />

(IgM) and complement 3 (C3)<br />

linear deposits of immunoglobulin G<br />

(IgG)<br />

nothing<br />

granular deposits of IgG and complement<br />

4 (C4)<br />

extensive fibrin strands<br />

60. A 26-year-old woman complains of burning<br />

retrosternal chest pain, radiating to the sides of<br />

the chest that is aggravated by bending forward.<br />

Which of the following is this pain most<br />

likely to arise from?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

heart<br />

lumbar spine<br />

intercostal nerves<br />

pancreas<br />

esophagus<br />

61. A 34-year-old woman has Raynaud’s phenomenon<br />

associated with systemic sclerosis

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