Internal-Medicine
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214 10: Infection<br />
82. Three individuals living on the same floor in a<br />
university dormitory residence develop symptoms<br />
and signs of pneumonia. The diagnosis is<br />
confirmed by CXR, and sputum samples are<br />
positive for S. pneumoniae. In an outbreak,<br />
which of the following conditions most likely<br />
predisposed these three individuals to developing<br />
pneumococcal pneumonia?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
immotile cilia syndrome<br />
previous viral infection<br />
asthma<br />
cigarette-induced chronic lung disease<br />
allergies<br />
83. A 78-year-old woman with a prior stroke is not<br />
feeling well. Her appetite is poor, and today her<br />
family noticed that she is confused so they sent<br />
her to the emergency room. She reports no<br />
cough, fever, or sputum production but her<br />
CXR reveals a left lower lobe infiltrate. Blood<br />
cultures are drawn, and she is started on antibiotics.<br />
The next day the cultures are positive for<br />
S. pneumoniae sensitive to penicillin. Which of<br />
the following is the most likely complication of<br />
pneumococcal pneumonia?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
peritonitis<br />
empyema<br />
pericarditis<br />
endocarditis<br />
osteomyelitis<br />
84. A 23-year-old woman presents with cough,<br />
malaise, and fever. She reports minimal whitish<br />
sputum production and now has chest soreness<br />
from coughing so much. She has no other<br />
past medical history and no risk factors for<br />
HIV. On examination, her temperature is<br />
38.3°C, pharynx is normal, and lungs are clear.<br />
CXR reveals diffuse bilateral infiltrates.<br />
Mycoplasma pneumonia is considered in the<br />
possible differential diagnosis of her pneumonia.<br />
Which other symptom besides cough is<br />
also prominent in patients with mycoplasma<br />
pneumonia?<br />
(A)<br />
(B)<br />
(C)<br />
sputum<br />
shortness of breath<br />
headache<br />
(D)<br />
(E)<br />
shaking chills<br />
pleuritic chest pain<br />
85 A 24-year-old woman has new symptoms of<br />
fever, headache, myalgia, and macular rash.<br />
She recently went on a camping trip with<br />
friends to the South-Central United States. She<br />
endured many “bug bites” during the trip but<br />
does not specifically recall any tick bites. The<br />
rash consists of macules 3 mm in size on her<br />
hands and feet. A clinical diagnosis of RMSF is<br />
made and she is started on treatment. Serology<br />
is drawn to confirm the diagnosis. Which of<br />
the following is the most likely causative<br />
organism?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
Gram-positive bacterium<br />
Gram-negative bacterium<br />
virus<br />
type of rickettsia<br />
type of chlamydia<br />
DIRECTIONS (Questions 86 through 105): Each<br />
set of matching questions in this section consists<br />
of a list of lettered options followed by several<br />
numbered items. For each numbered item, select<br />
the appropriate lettered option(s). Each lettered<br />
option may be selected once, more than once, or<br />
not at all. EACH ITEM WILL STATE THE NUM-<br />
BER OF OPTIONS TO SELECT. CHOOSE<br />
EXACTLY THIS NUMBER.<br />
Questions 86 through 90<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
beta-lactams (penicillins and<br />
cephalosporins)<br />
vancomycin<br />
erythromycin<br />
sulfonamides and trimethoprim<br />
ciprofloxacin<br />
For each mechanism of antibiotic action, select the<br />
most likely drug.<br />
86. Major cellular target is interference with cell<br />
metabolism (SELECT ONE)<br />
87. Work by inhibiting DNA synthesis (SELECT<br />
ONE)