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Internal-Medicine

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244 12: Diseases of the Respiratory System<br />

27. A 23-year-old man is experiencing a flare of his<br />

asthma. He is using his salbutamol inhaler<br />

more frequently than usual and despite increasing<br />

his inhaled steroids he is still short of<br />

breath. Previously his asthma was considered<br />

mild with no severe exacerbations requiring<br />

oral steroids or hospitalization. With his flare,<br />

he has recurrent episodes of bronchial obstruction,<br />

fever, malaise, and expectoration of<br />

brownish mucous plugs. On examination, there<br />

is bilateral wheezing. The heart, abdomen, neurologic,<br />

and skin exams are normal. CXR<br />

reveals upper lobe pulmonary infiltrates; the<br />

eosinophil count is 3000/mL, and serum precipitating<br />

antibodies to Aspergillus are positive.<br />

Which of the following is the most likely<br />

diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

ascaris infestation<br />

allergic bronchopulmonary aspergillosis<br />

Churg-Strauss allergic granulomatosis<br />

Löeffler’s syndrome<br />

hypereosinophilic syndrome<br />

28. A 34-year-old African American man presents<br />

with mild dyspnea on exertion and joint discomfort<br />

in his knees, wrists, and ankles. He also has a<br />

fever and red tender rash on his shins. Physical<br />

examination reveals hepatosplenomegaly, generalized<br />

lymphadenopathy, and tender erythematous<br />

nodules on his legs. CXR shows bilateral<br />

symmetric hilar adenopathy. Which of the following<br />

laboratory findings is not characteristic of<br />

this condition?<br />

following is also indicated in the management<br />

of this condition?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

meningococcal vaccination<br />

yearly influenza vaccination<br />

weight reduction if obese<br />

Haemophilus influenzae B vaccination<br />

pneumococcal vaccination<br />

30. A 45-year-old woman has severe symptoms of<br />

epigastric and abdominal pain after eating. A<br />

trial of acid suppression therapy with proton<br />

pump inhibitors (PPI) only partially improved<br />

her symptoms. She undergoes elective outpatient<br />

upper endoscopy, which is positive for a<br />

small duodenal ulcer. Two hours later, she is<br />

short of breath and complaining of severe anterior<br />

chest pain, which is made worse with deep<br />

inspiration. On examination, she looks unwell,<br />

blood pressure is 150/90 mm Hg, pulse<br />

110/min, and lungs are clear. Heart sounds are<br />

normal but an extra “crunching” type sound is<br />

intermittently heard. CXR demonstrates air<br />

surrounding the heart. Which of the following<br />

is the most likely diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

acute pericarditis<br />

acute cardiac ischemia<br />

acute mediastinitis<br />

aortic dissection<br />

pneumothorax<br />

31. Which of the following is most likely associated<br />

with cystic fibrosis in an adult patient?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

hyperglobulinemia<br />

elevated ACE level<br />

elevated sedimentation rate (ESR)<br />

elevated serum calcium<br />

normal gallium scan<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

spontaneous remission<br />

good pancreatic exocrine function<br />

hemoptysis<br />

rectal polyps<br />

normal sweat chloride<br />

29. A 66-year-old man has progressive shortness of<br />

breath due to COPD. He is currently able to<br />

do his activities of daily living, but has trouble<br />

walking more than one block. His physical<br />

examination reveals hyperinflation, increased<br />

resonance to percussion, and bilateral expiratory<br />

wheezes. He is on appropriate medical<br />

therapy for his stage of COPD. Which of the<br />

32. A 55-year-old woman is in the intensive care<br />

unit on a ventilator for hypoxemia following<br />

“flash” pulmonary edema. Her PO 2<br />

on the<br />

blood gas prior to intubation was 44 mm Hg,<br />

and now while breathing 100% oxygen on the<br />

ventilator her repeat blood gas reveals a PO 2<br />

of 80 mm Hg. Hypoxemia while receiving

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