Internal-Medicine
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276 14: Comprehensive Review<br />
6. A 30-year-old woman develops acute onset of<br />
erythema nodosum, fever, malaise, and<br />
anorexia. The chest x-ray (CXR) reveals bilateral<br />
hilar lymphadenopathy and a left paratracheal<br />
lymph node. Which of the following is<br />
the most likely diagnosis?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
acquired immune deficiency syndrome<br />
(AIDS)<br />
rheumatic fever<br />
sarcoidosis<br />
tuberculosis<br />
bronchogenic carcinoma<br />
7. Which of the following imaging techniques is<br />
best able to measure regional brain substrate<br />
uptake and metabolic kinetics?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
magnetic resonance imaging (MRI)<br />
computed tomography (CT)<br />
positron emission tomography (PET)<br />
serial thallium scintigrams<br />
Doppler ultrasound<br />
8. A 47-year-old man suddenly develops high<br />
fever and hypotension. He has a generalized<br />
erythematous macular rash, and over the next<br />
day, develops gangrene of his left leg. Which of<br />
the following is the most likely organism?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
Corynebacterium diphtheriae<br />
Streptococcus group C<br />
Neisseria gonorrhoeae<br />
Streptococcus group A<br />
Salmonella enteritidis<br />
9. A 56-year-old woman presents to the hospital<br />
because of symptoms of dyspnea, blurry<br />
vision, and headaches. On examination, her<br />
blood pressure is 210/130 mm Hg, heart rate<br />
100 beats/min, and oxygen saturation 95%.<br />
Her fundi reveal retinal hemorrhages and<br />
papilledema. The heart sounds are normal<br />
expect for an S 4<br />
, and the lungs have lower<br />
lobe crackles. Which of the following is the<br />
most appropriate agent to reduce her blood<br />
pressure?<br />
(A)<br />
(B)<br />
IV hydralazine<br />
IV labetalol<br />
(C)<br />
(D)<br />
(E)<br />
oral methyldopa<br />
IV diazoxide<br />
sublingual nifedipine<br />
10. A 56-year-old man complains of increased<br />
thirst and increased urinary volume and frequency.<br />
He has also noticed new symptoms of<br />
constipation and generalized aches and pains.<br />
He has no significant past medical problems<br />
and his physical examination is normal. Initial<br />
investigations consist of a normal complete<br />
blood count (CBC) fasting blood glucose and<br />
urinalysis. His sodium, urea, and creatinine are<br />
normal, but calcium is 12.4 mg/dL (8.4–10.2<br />
mg/dL). Further testing reveals an elevated<br />
PTH level. Which of the following is the most<br />
likely mechanism for the polyuria in this<br />
condition?<br />
(A) direct effect of PTH on the kidney<br />
(B) hypercalcemia-induced renal tubular<br />
acidosis (RTA)<br />
(C) hypercalcemia-induced chronic renal<br />
failure<br />
(D) hypercalcemia-induced defect in renal<br />
concentrating ability (nephrogenic diabetes<br />
insipidus)<br />
(E) hypercalcemia-induced defect in renal<br />
glucose handling<br />
11. A 13-year-old boy has periods when he seems<br />
to be unresponsive, associated with blinking<br />
of his eyes. These are momentary, and he seems<br />
normal thereafter. Which of the following is<br />
the most effective treatment?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
phenytoin<br />
carbamazepine<br />
phenobarbital<br />
gabapentin<br />
ethosuximide<br />
12. Which of the following lymphoid malignancies<br />
is invariably of B-cell origin?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
chronic lymphocytic leukemia (CLL)<br />
hairy cell leukemia<br />
Burkitt’s lymphoma<br />
mycosis fungoides<br />
angioimmunoblastic lymphadenopathy