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Internal-Medicine

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276 14: Comprehensive Review<br />

6. A 30-year-old woman develops acute onset of<br />

erythema nodosum, fever, malaise, and<br />

anorexia. The chest x-ray (CXR) reveals bilateral<br />

hilar lymphadenopathy and a left paratracheal<br />

lymph node. Which of the following is<br />

the most likely diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

acquired immune deficiency syndrome<br />

(AIDS)<br />

rheumatic fever<br />

sarcoidosis<br />

tuberculosis<br />

bronchogenic carcinoma<br />

7. Which of the following imaging techniques is<br />

best able to measure regional brain substrate<br />

uptake and metabolic kinetics?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

magnetic resonance imaging (MRI)<br />

computed tomography (CT)<br />

positron emission tomography (PET)<br />

serial thallium scintigrams<br />

Doppler ultrasound<br />

8. A 47-year-old man suddenly develops high<br />

fever and hypotension. He has a generalized<br />

erythematous macular rash, and over the next<br />

day, develops gangrene of his left leg. Which of<br />

the following is the most likely organism?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

Corynebacterium diphtheriae<br />

Streptococcus group C<br />

Neisseria gonorrhoeae<br />

Streptococcus group A<br />

Salmonella enteritidis<br />

9. A 56-year-old woman presents to the hospital<br />

because of symptoms of dyspnea, blurry<br />

vision, and headaches. On examination, her<br />

blood pressure is 210/130 mm Hg, heart rate<br />

100 beats/min, and oxygen saturation 95%.<br />

Her fundi reveal retinal hemorrhages and<br />

papilledema. The heart sounds are normal<br />

expect for an S 4<br />

, and the lungs have lower<br />

lobe crackles. Which of the following is the<br />

most appropriate agent to reduce her blood<br />

pressure?<br />

(A)<br />

(B)<br />

IV hydralazine<br />

IV labetalol<br />

(C)<br />

(D)<br />

(E)<br />

oral methyldopa<br />

IV diazoxide<br />

sublingual nifedipine<br />

10. A 56-year-old man complains of increased<br />

thirst and increased urinary volume and frequency.<br />

He has also noticed new symptoms of<br />

constipation and generalized aches and pains.<br />

He has no significant past medical problems<br />

and his physical examination is normal. Initial<br />

investigations consist of a normal complete<br />

blood count (CBC) fasting blood glucose and<br />

urinalysis. His sodium, urea, and creatinine are<br />

normal, but calcium is 12.4 mg/dL (8.4–10.2<br />

mg/dL). Further testing reveals an elevated<br />

PTH level. Which of the following is the most<br />

likely mechanism for the polyuria in this<br />

condition?<br />

(A) direct effect of PTH on the kidney<br />

(B) hypercalcemia-induced renal tubular<br />

acidosis (RTA)<br />

(C) hypercalcemia-induced chronic renal<br />

failure<br />

(D) hypercalcemia-induced defect in renal<br />

concentrating ability (nephrogenic diabetes<br />

insipidus)<br />

(E) hypercalcemia-induced defect in renal<br />

glucose handling<br />

11. A 13-year-old boy has periods when he seems<br />

to be unresponsive, associated with blinking<br />

of his eyes. These are momentary, and he seems<br />

normal thereafter. Which of the following is<br />

the most effective treatment?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

phenytoin<br />

carbamazepine<br />

phenobarbital<br />

gabapentin<br />

ethosuximide<br />

12. Which of the following lymphoid malignancies<br />

is invariably of B-cell origin?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

chronic lymphocytic leukemia (CLL)<br />

hairy cell leukemia<br />

Burkitt’s lymphoma<br />

mycosis fungoides<br />

angioimmunoblastic lymphadenopathy

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