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Internal-Medicine

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82 4: Gastroenterology<br />

23. A 64-year-old woman develops sudden-onset<br />

20. A 29-year-old man with acquired immune deficiency<br />

(E) more than 1000 white cells/mm 3 (E) dietary modification<br />

syndrome (AIDS) comes to the emergency<br />

department because of progressively increasing<br />

abdominal discomfort. Examination shows voluntary<br />

guarding in the upper abdomen. His biochemistry<br />

is normal except for an elevated<br />

amylase at 370 U/L (25–125 U/L). Which of the<br />

following infections can trigger this disorder in<br />

AIDS patients?<br />

abdominal discomfort after eating a large meal.<br />

The pain is constant, localizes to the epigastric<br />

area with radiation to her right scapula. She also<br />

has nausea and vomiting. It eventual subsides<br />

1 hour later. An ultrasound of the abdomen<br />

reveals a dilated common bile duct secondary<br />

to stones. Which of the following statements<br />

regarding common bile duct stones is most<br />

(A) toxoplasmosis<br />

likely true?<br />

(B) Mycobacterium avium complex<br />

(A) all originate in the gallbladder<br />

(C) Mycobacterium tuberculosis<br />

(B) always produce jaundice<br />

(D) Pneumocystis carinii<br />

(C) produce constant level of jaundice<br />

(E) herpes virus<br />

(D) can be painless<br />

(E) indicate anomalies of the bile duct<br />

21. A 55-year-old man from China is known to have<br />

chronic liver disease, secondary to hepatitis B<br />

infection. He has recently felt unwell, and his<br />

hemoglobin level has increased from 130 g/L, 1<br />

year ago, to 195 g/L. Which of the following is<br />

the most appropriate initial diagnostic test?<br />

24. A 53-year-old man presents with diarrhea. He<br />

also complains of facial flushing lasting minutes<br />

at a time. Physical examination reveals facial<br />

telangiectasias and a heart murmur not present<br />

2 years before. This murmur is accentuated by<br />

deep breathing. Which of the following is the<br />

(A) alkaline phosphatase<br />

most appropriate initial diagnostic test?<br />

(B) alpha-fetoprotein (AFP)<br />

(C) aspartate transaminase (AST)<br />

(A) urinary vanillylmandelic acid (VMA)<br />

(D) alanine transaminase (ALT)<br />

(B) serum noradrenaline levels<br />

(E) unconjugated bilirubin<br />

(C) barium enema<br />

(D) serum serotonin levels<br />

22. A 63-year-old man with a long history of alcohol<br />

abuse presents with ascites. He is experiencing<br />

(E) urinary 5-hydroxyindolacetic acid<br />

(5-HIAA)<br />

mild abdominal discomfort and nausea.<br />

Examination reveals tense ascites and generalized<br />

tenderness but no rigidity. A diagnostic<br />

paracentesis of the fluid is performed. Which of<br />

the following ascitic fluid results is most likely<br />

to suggest an uncomplicated ascites due to<br />

portal hypertension from cirrhosis?<br />

25. A 29-year-old woman complains of dysphagia<br />

with both solids and liquids, worse when she<br />

is eating quickly or is anxious. Manometry<br />

reveals normal basal esophageal sphincter<br />

pressure, with no relaxation of the sphincter<br />

on swallowing. Which of the following is the<br />

(A) hemorrhage<br />

most appropriate next step in management?<br />

(B) protein >25 g/L<br />

(A) beta-blocker therapy<br />

(C) bilirubin level twice that of serum<br />

(B) partial esophagectomy<br />

(D) serum to ascites albumin gradient<br />

(C) anticholinergic drugs<br />

>1.1 g/dL<br />

(D) calcium channel blockers

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