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Internal-Medicine

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Questions: 27–37 245<br />

100% oxygen indicates which of the following<br />

problems?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

ventilation-perfusion ratio inequality<br />

right-to-left shunt<br />

hypoventilation<br />

impaired diffusion<br />

interstitial lung disease<br />

33. A 31-year-old man with severe kyphoscoliosis<br />

due to cerebral palsy is experiencing worsening<br />

shortness of breath with exertion. On examination,<br />

he has a severe scoliosis to the left and<br />

decreased air entry to that side. His right lung<br />

is clear, JVP is 3 cm, and heart sounds are<br />

normal. Pulmonary function tests are performed.<br />

Which of the following is the most<br />

likely abnormality to be seen on the pulmonary<br />

function tests?<br />

(A) increased total lung capacity (TLC)<br />

(B) increased functional residual capacity<br />

(FRC)<br />

(C) decreased TLC<br />

(D) increased compliance<br />

(E) increased vital capacity (VC)<br />

34. A 67-year-old woman has pulmonary function<br />

tests performed to evaluate symptoms of dyspnea.<br />

The most prominent finding is a reduction<br />

of the ratio of FEV1/FVC. Which of the<br />

following is the most likely diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

COPD<br />

ankylosing spondylitis<br />

pickwickian syndrome<br />

scleroderma of the chest wall<br />

lobar pneumonia<br />

35. Which of the following statements concerning<br />

asbestosis is correct?<br />

(A)<br />

(B)<br />

(C)<br />

the type of asbestos fiber is crucial in<br />

determining whether asbestos-related<br />

lung disease occurs<br />

moderate rather than severe obstruction<br />

to airflow is characteristic of asbestosis<br />

mesothelioma is the common malignancy<br />

associated with asbestosis<br />

(D)<br />

(E)<br />

pleural effusions are invariably associated<br />

with malignancy in asbestosis<br />

short-term (i.e., 1–2 years) exposure can<br />

result in serious sequelae decades later<br />

36. A 52-year-old man develops sudden-onset<br />

shortness of breath on postoperative day 4 after<br />

a hemicolectomy for colon cancer. His surgery<br />

went well with no operative complications. He<br />

reports no cough, sputum, or pleuritic chest<br />

pain. His blood pressure is 155/90 mm Hg,<br />

pulse 100/min, temperature 37.8°C, lungs are<br />

clear, and heart sounds normal. He has bilateral<br />

pedal edema, but no discomfort in his legs. His<br />

CXR and ECG are normal. A chest CT with contrast<br />

reveals a thrombus in his right upper lobe<br />

artery. Which of the following statements concerning<br />

the management of this condition is<br />

most likely correct?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

continuous IV heparin or subcutaneous<br />

low-molecular-weight heparin (LMWH)<br />

therapy is indicated<br />

urgent thrombolytic therapy is indicated<br />

urgent inferior vena cava (IVC)<br />

filter insertion is indicated<br />

confirmation of the diagnosis with<br />

bilateral ultrasound leg Dopplers<br />

37. A 55-year-old woman presents with coughing<br />

up blood and sputum. She gives a history of<br />

recurrent pneumonias and a chronic cough<br />

productive of foul-smelling purulent sputum.<br />

The sputum production is worse on lying down<br />

and in the morning. On physical examination,<br />

she appears chronically ill with clubbing of<br />

the fingers. Wet inspiratory crackles are heard<br />

at the lung bases posteriorly. There are no<br />

hepatosplenomegaly or any palpable lymph<br />

nodes. CXR shows scaring in the right lower<br />

lobe, which on chest CT scan is identified as<br />

airway dilatation, bronchial wall thickening, and<br />

grapelike cysts. Which of the following is a recognized<br />

precursor to this patient’s condition?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

bronchial asthma<br />

cigarette smoking<br />

lung infection and impairment of drainage<br />

lung cancer<br />

silicosis

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