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Internal-Medicine

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246 12: Diseases of the Respiratory System<br />

38. A 50-year-old man presents with excessive daytime<br />

sleepiness and a history of snoring. One<br />

week ago, he fell asleep while driving his car<br />

and got into a minor accident. On examination,<br />

he is obese (body mass index [BMI] >30)<br />

and his blood pressure is 160/90 mm Hg. His<br />

lungs are clear and heart sounds are distant.<br />

Which of the following is the most likely explanation<br />

for the symptoms associated with this<br />

condition?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

related to cardiac dysfunction<br />

neuropsychiatric and behavioral<br />

pulmonary<br />

gastrointestinal (GI)<br />

musculoskeletal<br />

39. Which of the following statements concerning<br />

hypoxemia in COPD is correct?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

erythrocytosis is an appropriate<br />

compensation for hypoxemia, and<br />

phlebotomy will worsen symptoms<br />

nocturnal oxygen therapy is effective in<br />

producing symptomatic and<br />

hemodynamic improvement in severe<br />

hypoxia<br />

a PO 2<br />

of 58 mm Hg is an indication for<br />

continuous oxygen therapy<br />

a PO 2<br />

of 65 mm Hg or below is an<br />

indication for supplemental oxygen<br />

during air travel<br />

continuous supplemental oxygen<br />

improves functional ability but does not<br />

alter the natural history of obstructive<br />

airways disease with severe hypoxemia<br />

40. A 58-year-old steam pipe worker presents with<br />

a vague ache in the left chest and mild dyspnea<br />

of several months’ duration. There is dullness<br />

on percussion of the left chest associated with<br />

diminished breath sounds. His CXR is shown<br />

in Fig. 12–1. Which of the following is the most<br />

likely diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

pleural metastases<br />

Paget’s disease<br />

mesothelioma and asbestosis<br />

pleural effusion<br />

multiple myeloma<br />

41. A 23-year-old man presents with coughing up<br />

blood and sputum. He gives a history of recurrent<br />

pneumonias and a chronic cough productive<br />

of foul-smelling purulent sputum. The<br />

sputum production is worse when lying down<br />

and in the morning. On physical examination,<br />

he appears chronically ill with clubbing of the<br />

fingers. Wet inspiratory crackles are heard at<br />

the lung bases posteriorly. There are no<br />

hepatosplenomegaly or any palpable lymph<br />

nodes. CXR shows scaring in the right lower<br />

lobe, which on chest CT scan is identified as<br />

airway dilatation, bronchial wall thickening,<br />

and grapelike cysts. Which of the following is<br />

sometimes seen in this condition?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

Figure 12–1.<br />

lung cancer<br />

dextrocardia<br />

fungal infection<br />

carcinoid syndrome<br />

Hodgkin’s disease<br />

42. A 27-year-old man presents with chest pain<br />

and feeling unwell. He describes cough with<br />

blood-tinged sputum, chills, and fever of 2 days’<br />

duration. Physical findings reveal dullness and<br />

moist rales in the left lower chest. His CXR is<br />

shown in Fig. 12–2. Which of the following is<br />

the most likely diagnosis?

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