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Internal-Medicine

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28 1: Cardiology<br />

most useful initial investigation since it identifies<br />

individuals with ST-segment elevation who may<br />

be candidates for either thrombolysis or primary<br />

angioplasty (PCI). The troponins are important<br />

in diagnosing myocardial necrosis. The other<br />

investigations may be important in looking for<br />

alternate causes of chest pain once ST-elevation<br />

MI has been ruled out. (Fuster, pp. 1252, 1256)<br />

52. (C) Essential hypertension is the most likely<br />

diagnosis. A secondary cause for hypertension<br />

is found in only 10% of patients, with 90%<br />

labeled as essential. Current recommendations<br />

for initial workup of a hypertensive patient<br />

include serum chemistry (glucose, potassium,<br />

creatinine), urinalysis, and ECG. (Fuster, p. 1545)<br />

53. (C) Coarctation of the aorta is the diagnosis.<br />

There is a reverse 3 deformity of the<br />

esophagus, the belly of which represents the<br />

dilated aorta after the coarctation. The border<br />

of the descending aorta shows a medial indentation<br />

called the 3 or tuck sign, the belly of the<br />

3 representing the poststenotic dilation and<br />

the upper portion by the dilated subclavian<br />

artery and small transverse aortic arch. (Fuster,<br />

p. 1809)<br />

54. (B) Note the abnormal humped contour of the<br />

left ventricular border, with a curvilinear calcification<br />

following the abnormal cardiac contour.<br />

The presence of calcification in the<br />

ventricular wall and the abnormal left ventricular<br />

contour alerts one to the consideration of<br />

a ventricular aneurysm. (Fuster, pp. 1321–1322)<br />

55. (B) The cardiac rhythm is atrial flutter with 2:1<br />

AV conduction. QRS complexes occur with<br />

perfect regularity at a rate of about 150/min.<br />

Their normal contour and duration indicate<br />

that ventricular activation occurs normally via<br />

the AV junction-His-Purkinje system. (Fuster,<br />

pp. 841–842)<br />

56. (B) The PR interval of the first two complexes<br />

is normal at 0.20 seconds. The QRS duration is<br />

0.16 seconds. The third P wave is nonconducted.<br />

This cycle recurs in the remainder of<br />

the strip. This is second-degree heart block of<br />

the Mobitz type II variety. Note the wide QRS.<br />

When this type of heart block develops, either<br />

de novo or in the course of an AMI, a cardiac<br />

pacemaker is usually recommended, as the<br />

incidence of complete heart block is high in<br />

this situation. (Fuster, pp. 901–903)<br />

57. (D) The ST is depressed in leads II, III, aVF, and<br />

V4–V6. These nonspecific abnormalities do not<br />

indicate significant coronary heart disease,<br />

especially in an apprehensive young patient.<br />

Further evaluations should be guided by clinical<br />

circumstances. (Fuster, pp. 304–305)<br />

58. (E) The underlying rhythm is a regular sinus<br />

rhythm with a rate of 85 beats/min. The sinus<br />

rhythm is interrupted frequently by bursts of<br />

irregular ventricular, premature beats. The sinus<br />

rhythm is uninterrupted as can be determined<br />

by plotting the PP intervals, which are regular.<br />

The rhythm may be termed a chaotic ventricular<br />

arrhythmia or ventricular tachycardia. Its<br />

gross irregularity is unusual. Antiarrhythmic<br />

therapy is usually not indicated for nonsustained<br />

VT in the setting of thrombolytic treatment.<br />

(Fuster, pp. 876–877)<br />

59. (A) No atrial activity is detected. The ventricular<br />

rate is slightly irregular. Beat number 4 is<br />

a ventricular premature contraction. The T<br />

waves are tall and markedly peaked. This type<br />

of T wave is characteristic of hyperkalemia, as<br />

is absence of visible atrial activity.<br />

The potassium level was 8.2 mmol/L.<br />

(Fuster, p. 313)<br />

60. (A) Sudden death, defined as death within 1 hour<br />

of onset of symptoms, is usually caused by cardiac<br />

disease in middle-aged and elderly<br />

patients, but in younger age groups noncardiac<br />

causes predominate. There is a bimodal<br />

distribution in the population, with the first<br />

peak before 6 months of age (sudden infant<br />

death syndrome). The most common coronary<br />

artery finding is extensive chronic coronary<br />

atherosclerosis, although acute syndromes do<br />

occur. (Fuster, p. 1057)<br />

61. (B) Over 90% of hypertensives in the general<br />

population have essential hypertension. Only

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