Internal-Medicine
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Questions: 71–84 189<br />
fluid analysis revealed calcium pyrophosphate<br />
deposition disease crystals (CPPD). Which of<br />
the following methods is the most effective prophylaxis<br />
for this condition?<br />
(C)<br />
(D)<br />
(E)<br />
septic arthritis<br />
reactivation of RA<br />
calcium hydroxyapatite deposition<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
allopurinol<br />
continuous NSAIDs<br />
low-dose glucocorticoids<br />
continuous antibiotic therapy<br />
colchicine<br />
81. A 79-year-old woman on chronic hemodialysis<br />
presents with severe pain in her left knee. On<br />
examination, the knee is warm, swollen, and<br />
painful to move. Diagnostic joint aspiration is<br />
performed. Which of the following is the most<br />
likely finding in her joint fluid?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
uric acid crystals<br />
calcium pyrophosphate crystals (CPPD)<br />
calcium hydroxyapatite crystals<br />
calcium oxalate crystals<br />
crystallized urea<br />
82. An 81-year-old woman develops progressive<br />
pain and immobility of her right shoulder. A<br />
series of x-rays over 8 months reveals destruction<br />
of the shoulder joint and an aspiration<br />
reveals blood in the effusion. Her only other<br />
articular manifestations are mild episodes of<br />
pain in her knees. Which of the following is<br />
the most likely diagnosis?<br />
(A)<br />
(B)<br />
(C)<br />
(D)<br />
(E)<br />
a chronic bacterial infection<br />
uric acid deposition<br />
CPPD disease<br />
calcium oxalate deposition<br />
calcium hydroxyapatite deposition<br />
83. A 59-year-old woman with RA, under reasonable<br />
control with methotrexate, develops a hot,<br />
swollen, red knee. Joint aspiration removes<br />
10 cc of an opaque yellow-colored fluid with a<br />
white count of 100,000/µL, predominantly neutrophils.<br />
The joint fluid protein is high and glucose<br />
is much lower than blood. Which of the<br />
following is the most likely diagnosis?<br />
DIRECTIONS (Questions 84 through 88): Each set<br />
of matching questions in this section consists of a<br />
list of lettered options followed by several numbered<br />
items. For each numbered item, select the<br />
appropriate lettered option(s). Each lettered option<br />
may be selected once, more than once, or not at all.<br />
EACH ITEM WILL STATE THE NUMBER OF<br />
OPTIONS TO SELECT. CHOOSE EXACTLY THIS<br />
NUMBER.<br />
(A) polyarteritis nodosa (PAN)<br />
(B) Churg-Strauss disease<br />
(C) Henoch-Schönlein purpura<br />
(D) vasculitis associated with infectious<br />
diseases<br />
(E) vasculitis associated with connective<br />
tissue diseases<br />
(F) Wegener’s granulomatosis<br />
(G) giant cell arteritis<br />
(H) Kawasaki disease<br />
(I) Behçet’s syndrome<br />
For each patient with vasculitis syndrome, select<br />
the most likely diagnosis.<br />
84. A 48-year-old man presents with 3 weeks of<br />
fever, fatigue, and shortness of breath. He has<br />
a history of “nasal allergies” and asthma,<br />
which have been poorly controlled in the past<br />
month. Two days prior to presentation, he<br />
developed weakness in his left foot and it<br />
now “drags” when he walks. On examination,<br />
his blood pressure is 165/90 mm Hg,<br />
pulse 100/min, respirations 20/min, and<br />
lungs have bilateral expiratory wheezes.<br />
There is left foot drop, and the rest of the neurologic<br />
examination is normal. Laboratory<br />
evaluation reveals ESR of 90 mm/h, WBC of<br />
14,000/mL with 10% eosinophils, and 1+ proteinuria.<br />
A CXR shows bilateral pulmonary<br />
infiltrates. (SELECT ONE)<br />
(A)<br />
(B)<br />
uric acid deposition<br />
CPPD deposition