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Internal-Medicine

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Questions: 71–84 189<br />

fluid analysis revealed calcium pyrophosphate<br />

deposition disease crystals (CPPD). Which of<br />

the following methods is the most effective prophylaxis<br />

for this condition?<br />

(C)<br />

(D)<br />

(E)<br />

septic arthritis<br />

reactivation of RA<br />

calcium hydroxyapatite deposition<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

allopurinol<br />

continuous NSAIDs<br />

low-dose glucocorticoids<br />

continuous antibiotic therapy<br />

colchicine<br />

81. A 79-year-old woman on chronic hemodialysis<br />

presents with severe pain in her left knee. On<br />

examination, the knee is warm, swollen, and<br />

painful to move. Diagnostic joint aspiration is<br />

performed. Which of the following is the most<br />

likely finding in her joint fluid?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

uric acid crystals<br />

calcium pyrophosphate crystals (CPPD)<br />

calcium hydroxyapatite crystals<br />

calcium oxalate crystals<br />

crystallized urea<br />

82. An 81-year-old woman develops progressive<br />

pain and immobility of her right shoulder. A<br />

series of x-rays over 8 months reveals destruction<br />

of the shoulder joint and an aspiration<br />

reveals blood in the effusion. Her only other<br />

articular manifestations are mild episodes of<br />

pain in her knees. Which of the following is<br />

the most likely diagnosis?<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

a chronic bacterial infection<br />

uric acid deposition<br />

CPPD disease<br />

calcium oxalate deposition<br />

calcium hydroxyapatite deposition<br />

83. A 59-year-old woman with RA, under reasonable<br />

control with methotrexate, develops a hot,<br />

swollen, red knee. Joint aspiration removes<br />

10 cc of an opaque yellow-colored fluid with a<br />

white count of 100,000/µL, predominantly neutrophils.<br />

The joint fluid protein is high and glucose<br />

is much lower than blood. Which of the<br />

following is the most likely diagnosis?<br />

DIRECTIONS (Questions 84 through 88): Each set<br />

of matching questions in this section consists of a<br />

list of lettered options followed by several numbered<br />

items. For each numbered item, select the<br />

appropriate lettered option(s). Each lettered option<br />

may be selected once, more than once, or not at all.<br />

EACH ITEM WILL STATE THE NUMBER OF<br />

OPTIONS TO SELECT. CHOOSE EXACTLY THIS<br />

NUMBER.<br />

(A) polyarteritis nodosa (PAN)<br />

(B) Churg-Strauss disease<br />

(C) Henoch-Schönlein purpura<br />

(D) vasculitis associated with infectious<br />

diseases<br />

(E) vasculitis associated with connective<br />

tissue diseases<br />

(F) Wegener’s granulomatosis<br />

(G) giant cell arteritis<br />

(H) Kawasaki disease<br />

(I) Behçet’s syndrome<br />

For each patient with vasculitis syndrome, select<br />

the most likely diagnosis.<br />

84. A 48-year-old man presents with 3 weeks of<br />

fever, fatigue, and shortness of breath. He has<br />

a history of “nasal allergies” and asthma,<br />

which have been poorly controlled in the past<br />

month. Two days prior to presentation, he<br />

developed weakness in his left foot and it<br />

now “drags” when he walks. On examination,<br />

his blood pressure is 165/90 mm Hg,<br />

pulse 100/min, respirations 20/min, and<br />

lungs have bilateral expiratory wheezes.<br />

There is left foot drop, and the rest of the neurologic<br />

examination is normal. Laboratory<br />

evaluation reveals ESR of 90 mm/h, WBC of<br />

14,000/mL with 10% eosinophils, and 1+ proteinuria.<br />

A CXR shows bilateral pulmonary<br />

infiltrates. (SELECT ONE)<br />

(A)<br />

(B)<br />

uric acid deposition<br />

CPPD deposition

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