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Internal-Medicine

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Questions: 82–99 215<br />

88. Resistance can be caused by drug inactivation<br />

(SELECT ONE)<br />

89. Work by inhibiting protein synthesis (SELECT<br />

ONE)<br />

90. Decreased intracellular accumulation can result<br />

in resistance (SELECT ONE)<br />

Questions 91 through 95<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

(F)<br />

erythromycin<br />

ciprofloxacin<br />

tetracycline<br />

sulfonamides<br />

metronidazole<br />

rifampin<br />

For each antibiotic side effect, select the most likely<br />

drug.<br />

91. Can cause unwanted pregnancy (SELECT<br />

ONE)<br />

92. Can contribute to hypoglycemia in non-insulindependent<br />

diabetes mellitus (NIDDM)<br />

(SELECT ONE)<br />

93. Can cause severe reaction to alcohol (SELECT<br />

ONE)<br />

94. Drug interaction can result in rejection for<br />

transplant recipients (SELECT ONE)<br />

95. Can result in phenytoin toxicity (SELECT ONE)<br />

Questions 96 through 100<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

(F)<br />

(G)<br />

(H)<br />

brucellosis<br />

coccidioidomycosis<br />

histoplasmosis<br />

leprosy<br />

leptospirosis<br />

infectious mononucleosis<br />

TB<br />

tularemia<br />

For each of the following patients, select the most<br />

likely diagnosis.<br />

96. A previously healthy 43-year-old man presents<br />

with symptoms of cough, fever, weight loss,<br />

and lymphadenopathy for the past 2 months.<br />

His physical examination reveals multiple axillary<br />

and cervical lymph nodes and oropharyngeal<br />

ulcerations. His CXR reveals fibronodular<br />

pulmonary infiltrates in the apex, his sputum is<br />

negative for TB, and the HIV test is negative. A<br />

bronchoalveolar lavage (BAL) confirms the<br />

diagnosis. (SELECT ONE)<br />

97. A 34-year-old man presents with fever, cough,<br />

and sputum production. The CXR reveals a<br />

thin-walled pulmonary cavity. His tests for TB<br />

and HIV are negative. Four weeks ago, he was<br />

traveling in southern California, including visiting<br />

the San Joaquin valley. While there he did<br />

experience a “flu-like” illness, which slowly<br />

improved but then his symptoms of cough and<br />

sputum started. A BAL confirmed the diagnosis.<br />

(SELECT ONE)<br />

98. A 42-year-old man presents with symptoms of<br />

cough, sputum, fever, and weight loss. His<br />

CXR reveals upper lobe pulmonary infiltrates<br />

and his Mantoux test (purified protein derivative<br />

[PPD]) is positive. He emigrated from<br />

Southeast Asia 3 years ago. (SELECT ONE)<br />

99. A 25-year-old woman presents with fever, night<br />

sweats, and muscles aches for the past 1 month.<br />

She was previously well. On examination, she<br />

has axillary and cervical lymph nodes, but no<br />

active joints or hepatosplenomegaly. She currently<br />

works on a hog farm. Her investigations<br />

are negative for EBV, CMV, and HIV. Serologic<br />

tests for the infecting agent confirm the diagnosis<br />

in her. (SELECT ONE)

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