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Internal-Medicine

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128 6: Oncology<br />

Questions 60 through 63<br />

(A)<br />

(B)<br />

(C)<br />

(D)<br />

(E)<br />

(F)<br />

(G)<br />

nonsteroidal anti-inflammatory drugs<br />

(NSAIDs)<br />

opioids<br />

amphetamines<br />

anticonvulsants<br />

phenothiazines<br />

butyrophenones<br />

steroids<br />

For each patient with metastatic cancer pain, select<br />

the most likely treatment choice.<br />

60. A 52-year-old woman has metastatic breast<br />

cancer with boney metastases. She is taking<br />

hydromorphone for the pain but is still experiencing<br />

back pain. She is reluctant to take more<br />

of the hydromorphone since she become very<br />

drowsy with higher doses. This group of medications<br />

is particularly useful for pain from<br />

bony metastases. (SELECT ONE)<br />

61. A 74-year-old man with metastatic prostate<br />

cancer develops shooting pains in his left leg<br />

and constant back pain. Further evaluation<br />

reveals a pathologic compression fracture of the<br />

lumbar spine and involvement of the nerve<br />

roots in his lower spine causing the pain. He is<br />

started on a medication to help reduce the symptoms,<br />

but a limitation of the drug is leukopenia<br />

and thrombocytopenia. (SELECT ONE)<br />

62. A 68-year-old woman was treated for<br />

melanoma 3 years ago. She now presents with<br />

constant headaches, nausea, vomiting, and leftsided<br />

weakness. A CT scan reveals two masses<br />

in the right parietal lobe consistent with<br />

metastatic melanoma. She is started on medication<br />

to help reduce her symptoms of<br />

headaches and nausea. (SELECT ONE)<br />

63. A 65-year-old man has metastatic lung cancer<br />

and severe bone and chest pain. He is started on<br />

morphine and ibuprofen to control the pain but<br />

is still not comfortable. Further gradual increases<br />

in the morphine dose achieve good pain control<br />

but he becomes drowsy on the appropriate dose<br />

and is unable to do much. He is started on a<br />

medication that can be useful in controlling<br />

opioid-induced sedation. (SELECT ONE)

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