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Internal-Medicine

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Answers: 9–28 25<br />

18. (A) The myxoma is a solitary globular or polypoid<br />

tumor varying in size from that of a<br />

cherry to a peach. About 75% are found in the<br />

left atrium, and most of the remainder in the<br />

right atrium. The clinical presentation is with<br />

one or more of the classical triad of constitution<br />

symptoms (fatigue, fever, anemia),<br />

embolic events, or obstruction of the valve<br />

orifice. (Fuster, pp. 2081–2082)<br />

19. (A) Diltiazem and verapamil may be of help in<br />

both acute paroxysms of atrial flutter and<br />

chronic management. The other choices have<br />

no effect on the AV node to slow down flutter,<br />

and atropine accelerates AV conduction. At<br />

times, catheter ablation of the flutter pathway<br />

is required in chronic atrial flutter. Surgical<br />

ablation is reserved for cases where other surgical<br />

interventions are required. (Fuster, p. 844)<br />

20. (C) Exercise electrocardiography represents an<br />

increasingly popular noninvasive method for<br />

early detection of latent ischemic heart disease.<br />

As with other diagnostic tests, the exercise ECG<br />

is of most clinical value when the pretest probability<br />

of disease is moderate (i.e., 30–70%). In<br />

men over 40 and women over 50 who plan to<br />

start vigorous exercise, use of exercise ECG is<br />

possibly, but not definitely, supported by the<br />

evidence (class IIb). (Fuster, pp. 477–478)<br />

21. (D) Contrast media used in cardiac catheterization<br />

may result in renal impairment. The<br />

group at highest risk includes diabetics with<br />

renal disease and those with preexisting renal<br />

failure. Good hydration is essential. Other manifestations<br />

of contrast media include nausea<br />

and vomiting (common), and anaphylactoid<br />

reactions characterized by low-grade fever,<br />

hives, itching, angioedema, bronchospasm, and<br />

even shock. Side effects are reduced with the<br />

use of new low osmolality contrast media.<br />

(Fuster, p. 489)<br />

22. (E) Pericarditis in clinical practice is commonly<br />

idiopathic and frequently assumed to be of possible<br />

viral origin. Coxsackieviruses are a<br />

common cause, but herpesviruses are not.<br />

Although TB, rheumatic fever, and MI can<br />

cause pericarditis, they are unlikely in this case.<br />

(Fuster, p. 1979)<br />

23. (C) Left-heart catheterization is a more accurate<br />

measurement, but involves a slightly increased<br />

risk. End-expiratory PA diastolic pressure is<br />

very close (2–4 mm) to wedge pressure as well.<br />

A discordance between wedge pressure and<br />

PA diastolic pressure suggests the presence of<br />

pulmonary hypertension. (Fuster, p. 512)<br />

24. (C) Aortic dissection is a medical emergency<br />

requiring prompt attention. Other cardiac and<br />

pulmonary causes of chest pain can be quickly<br />

ruled out with ECG and CXR. CT scan of the<br />

chest is sensitive (93–100%) in ruling out dissection.<br />

Transesophageal echocardiography is<br />

equally as sensitive but not a transthoracic<br />

echo. (Fuster, pp. 2312–2313)<br />

25. (A) This is characteristic of an atrial septal<br />

defect. Pulmonary blood flow is greater<br />

because of increased blood flow from the right<br />

atrium, which receives blood from the vena<br />

cava and left atrium. (Fuster, pp. 1797–1798)<br />

26. (B) Angina or infarction in young patients<br />

should prompt the physician to consider congenital<br />

coronary artery anomaly or congenital<br />

coronary artery aneurysm. Acquired coronary<br />

artery aneurysm can be caused by atherosclerosis,<br />

trauma, angioplasty, atherectomy, vasculitis,<br />

mycotic emboli, Kawasaki syndrome,<br />

or arterial dissection. (Fuster, p. 1178)<br />

27. (D) This pulse is seen in aortic regurgitation.<br />

The pressure in diastole is usually 50 mm<br />

Hg or lower. This is known as a water hammer<br />

or Corrigan’s pulse. A bisferiens pulse (in<br />

the bisferiens wave form there are two pressure<br />

peaks) may be present as well. Systolic<br />

blood pressure is elevated. (Fuster, p. 1654)<br />

28. (B) Digoxin toxicity may cause any dysrhythmia.<br />

Classically, dysrhythmias that are associated<br />

with increased automaticity and decreased<br />

AV conduction occur (i.e., paroxysmal atrial<br />

tachycardia with 2:1 block, accelerated junctional<br />

rhythm, or bidirectional ventricular tachycardia<br />

[torsade de pointes]). Sinus bradycardia

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