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MARTES / TUESDAY<br />

28<br />

7. Greer K.W., Hamilton J.V., Cheal E.J,<br />

“Polyethylene wear in orthopaedics” in<br />

Encyclopaedic Handbook of biomaterials<br />

and bioengineering, Part B: Applications,<br />

Volume 1, (DL.Wise et alumina; editors),<br />

Marcel Dekker, Inc., pp. 613-638, 1995.<br />

8. Plitz W., Walter A., “Tribological aspects<br />

of metal/polymer couplings”, in Technical<br />

principles, design and safety of joint<br />

implants (G. Buchhorn, H-G. Willert,<br />

eds.), Hogrefe &Huber Publishers, 82-<br />

89, 1994.<br />

9. Algan S.M., Horowitz S.M., “Biology of<br />

aseptic loosening of the cemented arthroplasty”<br />

in Encyclopaedic Handbook<br />

of biomaterials and bioengineering, Part<br />

B: Applications, Volume 1, (DL.Wise et<br />

alumina; editors), Marcel Dekker, Inc., pp.<br />

773-797, 1995.<br />

10. Viceconti M., Cavallotti G., Andrisano A.,<br />

Toni A., “Discussion on the design of a <strong>hip</strong><br />

joint simulator”, Med. Eng. Phys. 18, No.3,<br />

234-240, 1996.<br />

11. Ben Abdallah A., Treheux D., “Friction<br />

and wear of ultrahigh molecular weight<br />

polyethylene against various new ceramics”,<br />

Wear 142, 43-56, 1991.<br />

12. Suh N., Mosleh M., Arinez J., “Tribology<br />

of polyethylene homocomposites”, Wear<br />

214, 231-236, 1998.<br />

13. Streicher M., “Tribology of artifi cial joints”,<br />

in “Endoprosthetics” (E. Morscher, editor),<br />

Springer Verlag, 1995.<br />

ALTERNATIVE BEARING<br />

MATERIALS:<br />

HIGHLY CROSS-LINKED<br />

POLY/METAL ON METAL/<br />

CERAMIC ON CERAMIC<br />

D. A. Dennis, M.D.<br />

Adjunct Professor, Dept. of Biomedical<br />

Engineering, University of Tennessee<br />

Assistant Clinical Professor, University<br />

of Colorado Health Sciences Center<br />

Clinical Director, Rocky Mountain Musculoskeletal<br />

Research Laboratory<br />

Denver, Colorado, USA<br />

I. Bearing Surfaces and Wear Particle-Induced<br />

Osteolysis<br />

A.The Problem<br />

- Improved fi xation of implants in the 1980’s<br />

has unmasked another limitation of THA…<br />

wear particle induced osteolysis<br />

“The presence of macrophages at the interface<br />

is a tissue response that no implant<br />

surgeon can lightly dismiss.” 32<br />

- Production of osteolytic mediators and<br />

metabolic byproducts by histiocytes is<br />

stimulated by phagocytosis of particulate<br />

debris. 7,72,86,100,102<br />

• Particulate biomaterials including the<br />

articulating surface, bone cement, and<br />

porous metal fi xation surfaces have all<br />

been implicated. 7,86,124,125,174,175<br />

• Ultra-High Molecular Weight Polyethylene<br />

is now widely perceived as the most<br />

signifi cant particle in wear induced bone<br />

resorption and the ultimate cause of failure<br />

of many implants. 7,86,124,125,174,175<br />

• How much polyethylene wear is too<br />

much?<br />

• Osteolysis is associated with linear wear<br />

rates >0.2mm/year in both cemented<br />

THA 149,218 and cementless THA 208,216<br />

• Minimal osteolysis when linear wear <<br />

0.1mm/year 149,208,216,218

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