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MARTES / TUESDAY<br />

70<br />

only be used for the older patient of 65 years<br />

or more. Some excellent long term results<br />

have been obtained in patients who had some<br />

other limiting factor from a young age that<br />

prevented them attaining a high mileage each<br />

year. We all know the problems of osteolysis<br />

related to the polythene debris from a metal<br />

on polythene joint. It is for these reasons<br />

there is again a logical argument for using<br />

a metal on metal articulation in the younger<br />

and active patient.<br />

The Outcome Centre at Oswestry has been<br />

following 5000 patients now out to 9 years.<br />

This is an independent review where information<br />

is gathered directly from patients.<br />

This has found a very high level of function<br />

and activity in patients with metal on metal<br />

resurfacing <strong>hip</strong> replacement. There is good<br />

survival out to 9 years with 97% survival at a<br />

minimum of 7 years. This group of patients is<br />

from a combined series of several surgeons<br />

across the world who are new to using this<br />

technique.<br />

Similarly, I have excellent results now out<br />

to 10 years with the Metasul articulation on<br />

a Thrust Plate. This is the shortest possible<br />

uncemented stem with strong initial stability<br />

and rigidity. These patients likewise have a<br />

high level of activity and the 8 year follow up<br />

was 98% survival.<br />

What of the metal ions absorbed? Certainly<br />

in a minority of patients these have a hypersensitivity<br />

response which causes pain and<br />

cyst formation. All patients absorb some<br />

metal in the form of chromium and cobalt.<br />

These levels are highest in the joint and<br />

adjacent to the metal implants. Alterations<br />

in circulating cells have been noted and this<br />

causes concern. However, the observation<br />

of a local sarcoma adjacent to a metal implant<br />

is very rare indeed considering the numbers<br />

implanted worldwide and this includes a<br />

whole range of metal implants. The observation<br />

therefore is that in practice and indeed<br />

over many years it is unlikely that the risk of<br />

a local cancer is signifi cant. Further observations<br />

and studies are needed to identify and<br />

quantify risks of leukaemia.<br />

METAL-METAL BEARING<br />

SURFACES: THE WAY<br />

OF THE FUTURE?<br />

S. J. MacDonald, MD, R. W. Mc-<br />

Calden, MD, R. B. Bourne, M.D.,<br />

C. H. Rorabeck, M.D., D. Chess, M.D.<br />

Health Sciences Centre, Ontario, Canada<br />

Objective: Polyethylene wear continues<br />

to be the most signifi cant issue following<br />

total <strong>hip</strong> arthroplasty (THA) leading to the<br />

current increase in use of alternative bearing<br />

surfaces. We performed a prospective,<br />

randomized, blinded clinical trial comparing<br />

metal versus polyethylene bearing surfaces<br />

in patients receiving THA.<br />

Method: Forty-one patients were randomized<br />

to receive a metal (23) or a polyethylene<br />

(18) insert with identical femoral and acetabular<br />

components. Patients were evaluated<br />

pre-operatively, at 3, 6, 12 months and annually<br />

thereafter, including an evaluation of<br />

erythrocyte and urine cobalt, chromium, and<br />

titanium, outcome measures (WOMAC, SF-<br />

12, Harris Hip Score) and radiographs.<br />

Results: No patients were lost to follow-up.<br />

At an average 7.2 (range 6.1 – 7.8) years<br />

follow-up there were no differences in any<br />

outcome measures or radiographic fi ndings.<br />

Patients receiving metal liners had signifi -<br />

cantly elevated metal ion measurements. At<br />

most recent follow-up erythrocyte cobalt levels<br />

were 7 times elevated (median 1.2 ∗g/L<br />

(metal) vs 0.18 ∗g/L (poly), p

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