l - People

Table of tables
Table 2.1: Amino acid frequency of occurrence in hinges 96
Table 2.2: Proximity to active sites 97
Table 2.3: Secondary Structure 98
Table 2.4: Physicochemical class 99
Table 2.5: Conservation 100
Table 2.6: Solvent accessibility 101
Table 2.7: Number of hinge points per protein in the Hinge Atlas 102
Table 2.8: Statistical analysis of HingeSeq predictor. 103
Table 2.9: GO terms 104
Table 2.10: Manual vs. computer annotated sets 105
Table 3.1: Summary of predictor results. 157
Table 3.2: Summary of two-cut predictor results under the loose criterion (14-residue
window). 158
Table 4.1: Predictors at a glance. 231
Table 4.2: Fitting of HingeMaster parameters 232
Table 4.3: Performance of the predictors against the Hinge Atlas Gold annotation. 234
Table 4.4: Summarized performance under the loose criterion. 235
Table 4.5: Predictor results for individual proteins. 236
Table 5.1: MolMovDB ID, PDB ID, free energy of binding, and sRMSD for redocked,
starting, and predicted structures. 273
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