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Figure 2.7: Solvent accessible surface area
Hinge residues tend to be on the surface, since steric clashes would often prevent them
from being in the core. We computed the solvent accessible surface area for the
backbone atoms of all residues in the Hinge Atlas and binned the residues by this
quantity. Bin #1 contains the 20% of all residues with the largest solvent accessible
surface area, and bin #5 contains the 20% of residues with the smallest solvent accessible
surface area. The first two bins (together representing the 40% of residues with highest
surface area) are enriched with hinges in a highly significant manner. Conversely, the
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