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Figure 3.6: cAMP-dependent protein kinase (open)<br />

Morph ID: f048180-370 PDB ID: 1ctp<br />

Hinge Atlas Gold hinges: 31-32,119-120,319-320<br />

b. Zheng et al. identify the boundaries of the small lobe as residues 40 and 127, slightly<br />

different from HAG. The single-cut predictors had significant minima near residue 120,<br />

with more ambiguous results for the other two hinges.<br />

c. 2-cut FlexOracle primary prediction: residues 314-317.<br />

Others:<br />

30-33,62-65<br />

42-45,82-85<br />

122-125<br />

The 2-cut predictor was partially successful. The primary prediction coincides with one<br />

of the hinges, as does the fourth prediction , and one of the second predictions. There are<br />

also three false positives (62-65 and 42-45, and 82-85) among the higher predictions.<br />

150

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