The Development of Circadian Rhythms in Human Infants

List of Tables
Table 3.1 - Description of demographic data for infants and families ........................ 88
Table 6.1 - Distribution of day time (unlogged values) cortisol secretion as a
percentage of total cortisol (day plus night cortisol) for 34 infants for each
week of age studied ........................................................................................ 135
Table 6.2 - Distribution of day time (unlogged values) cortisol secretion as a
percentage of total cortisol (day plus night cortisol), relative to temperature
maturity, for 34 infants for each week of age studied .................................... 141
Table 7.1 - Definitions of sleep parameters used by Actiwatch ................................ 146
Table 8.1 - H3f3b/GAPDH ratio clock gene values for infant 16003 taken on weeks 8,
10 -15; six hourly samples taken over 48 hours per week of measurement,
where available. ............................................................................................. 172
Table 9.1 - Univariate linear model for infant sleep efficiency with place of sleep and
age of physiological maturity as predictor values. ......................................... 188
Table 9.2 - Effect of maternal age on age of achievement of physiological
development of mature infant core body temperature ................................... 188
Table 9.3 - Effect of family occupancy in social housing on age of achievement of
physiological maturity of infant temperature ................................................. 189
Table 9.4 - Effect of infant episode of illness in postnatal period on night time
melatonin secretion ........................................................................................ 190
Table 9.5 - Effect of socioeconomic status of family on night time melatonin secretion
of infants ........................................................................................................ 190
Table 9.6 - Effect of measured infant sleep parameters on night time melatonin
secretion ......................................................................................................... 193
Table 10.1 - Temporal relationship of parameters measured in 35 human infants from
5 to 18 weeks of age. Mean values for age of maturation of circadian rhythm
in overnight temperature control during sleep, evening peak in melatonin
secretion, morning peak in cortisol secretion, timing of maximum sleep
efficiency and maximum peripheral clock gene expression (by amplitude and
R2 goodness of fit). ........................................................................................ 201
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