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Milena C. Lo Giudice have on the child. The informed consent process for the parents/legal representatives of the child should assist the parents/legal representatives in understanding the health needs of the child and the potential benefits and risks of the research on the child-participant. The parents/legal representatives should confirm their consent by signing a consent form, except in cases where the laws and standard practices do not require written consent. 15. When the child-participant is not legally able to consent, the consent of the parents/legal representatives is required. This consent should reflect both the will of the child as well as that of the parents/ legal representatives. The withholding or withdrawal of consent by the parents/legal representatives should be fully respected. 16. In exceptional circumstances (e.g. the investigation of the use of emergency medicines in children), the consent of a relative other than the parents/legal representatives may be sought. In such cases, the (potential) child-participant should be, as far as possible, fully informed and his/her assent sought. The retrospective consent of the parents/legal guardians should be sought as soon as possible. 17. In general, the consent of both parents should be sought prior to enrolling a child in a biomedical research project. However, where the law permits, the consent of one parent may be considered adequate. 18. The written and oral information to be provided to children and their parents/legal representatives, as well as the processes by which this information will be conveyed and discussed, must be reviewed and receive a positive decision from an appropriately constituted and operating ethics committee. The ethics committee must include or seek the advice of a paediatrician not involved in the proposed research. Approved by the CESP, May 4th 2002. 5) Conclusion Physicians have an ethical (and legal) obligation to obtain parental permission to undertake recommended medical interventions and clinical trials. In many circumstances, physicians should also solicit a patient assent when developmentally appropriate. In cases involving emancipated or mature minors with adequate decision-making capacity, or when otherwise permitted by law, physicians should seek informed consent directly from patients. Страна 12
Novini vo pedijatrijata / Godi[na revija 2009 REFERENCES 1. Committee for Proprietary Medicinal Products /CPMP) (1997) Note for guidance on clinical investigations of medicinal products in children (CPMP/EWP/462/95) London 1997. 2. Council for International Organisations of Medical Sciences (CIOMS) in collaboration with the World Health Organisation (WHO) (1993), International ethical guidelines for biomedical research involving human subjects. 3. American Academy of Pediatrics Committee on Bioethics. Informed consent, parental permission, and assent in pediatric practice. Pediatrics 1995;95(2):314-7. 4. Dennis Gill Æ Ethics Working Group of the Confederation of European Specialists in Paediatrics, Guidelines for informed consent in biomedical research involving paediatric populations as research participants, Eur J Pediatr (2003) 162: 455–458, DOI 10.1007/s00431-003-1192-0 5. The World Medical Association’s Declaration Of Helsinki, Seoul 2008 Страна 13
Page 1 and 2: NOVINI VO PEDIJATRIJATA GODI{NA REV
Page 3: Od glavniot redaktor Po~ituvani kol
Page 6 and 7: Mladenović M, Radlović N, Lekovi
Page 8 and 9: Milena C. Lo Giudice Although all t
Page 10 and 11: Milena C. Lo Giudice patient will h
Page 14 and 15: Страна 14
Page 16 and 17: Nedeqko Radlovi] nje. Budući da su
Page 18 and 19: Nedeqko Radlovi] (maksimalno 15 mg
Page 20 and 21: Gjeorgjina Kuli-Lito Introduction K
Page 22 and 23: Gjeoorgjina Kuli-Liito The fever ty
Page 24 and 25: Gjeorgjina Kuli-Lito stenoses in ch
Page 28 and 29: @eqko Ron~evi] Will stethoscope sur
Page 30 and 31: @eqko Ron~evi] Electronic stethosco
Page 32 and 33: @eqko Ron~evi] 8. Mangione S, Duffy
Page 34 and 35: Nada Pop-Jordanova a critical role
Page 36 and 37: Nada Pop-Jordanova response (long-t
Page 38 and 39: Nada Pop-Jordanova In the following
Page 40 and 41: Nada Pop-Jordanova From Fig. 4 it i
Page 42 and 43: Nada Pop-Jordanova References: [1]
Page 44 and 45: Nada Pop-Jordanova [22] Friesen GM,
Page 46 and 47: Mirjana Ko~ova Ha[imoto tiroiditis
Page 48 and 49: Mirjana Ko~ova Slika 2. Devoj~e na
Page 50 and 51: Mirjana Ko~ova c) Ultrazvu~niot pre
Page 52 and 53: Mirjana Ko~ova smetaat deka kaj ovi
Page 54 and 55: Mirjana Ko~ova 10. Pituitary pseudo
Page 58 and 59: Qup~o Nikolovski Summary: Regardles
Page 60 and 61: Qup~o Nikolovski Sugeriran antibiot
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Qup~o Nikolovski - Toj moè da se k
Page 64 and 65:
Qup~o Nikolovski Sugeriran reìm Pr
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Qup~o Nikolovski decata so akcent n
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Qup~o Nikolovski Antibiotici i dija
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Страна 70
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Sowa Peova Abstrakt Efikasno rano o
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Sowa Peova Ranoto klini~ko prepozna
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Sowa Peova - In vitro analiza na in
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Sowa Peova metodi pred da se pojava
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Sowa Peova Страна 80
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Страна 82
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Dafina Kuzmanovska bubre`na insufic
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Dafina Kuzmanovska 1. Abnormalen ra
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Dafina Kuzmanovska Isto taka, nema
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Dafina Kuzmanovska 11. Feather AS,
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Aco Kostovski na holestaza ne se pr
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Aco Kostovski dukcijata na SREBP -
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Aco Kostovski niraat sintezata na l
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Aco Kostovski lema neselektirana st
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Aco Kostovski 2. Tip 1 ili 2 diabet
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Aco Kostovski parcijalna lipodistro
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Aco Kostovski patis od drugi mo`ni
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Aco Kostovski Lipoproteini so mala
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Aco Kostovski kontrola na obeznosta
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Aco Kostovski za razlika od general
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Aco Kostovski NEALKOHOLNA MASTNA BO
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Lekovi] Z. SY GILBERT IN CHILDREN:
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Страна 116
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Aspazija Sofijanova ABSTRAKT Mnogu
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Aspazija Sofijanova en~iwa. Zatoa d
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Aspazija Sofijanova Odgovor na Krat
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Aspazija Sofijanova cira so seriozn
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Aspazija Sofijanova sporo. Hepati~n
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Aspazija Sofijanova asociran so pos
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Aspazija Sofijanova 16. Meyer PG, O
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Aspazija Sofijanova 48. Goldman HB.
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Страна 134
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Du[ko Fidanovski Abstract With intr
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Du[ko Fidanovski dilna teìna od 50
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Du[ko Fidanovski koncentracii pomal
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Du[ko Fidanovski Lekuvawe so surfak
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Du[ko Fidanovski EMRT i golem rizik
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Du[ko Fidanovski 17. Kotecha S, Wil
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Du[ko Fidanovski 46. Corbet A, Long
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Страна 150
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Filip Duma fluid. Precise diagnose
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Filip Duma rata i mozo~noto tkivo,
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Filip Duma Diskusija i rezultati: K
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Kata Martinova endokrinite `lezdi i
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Kata Martinova Evaluacija i monitor
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Kata Martinova SQUID (superconducti
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Kata Martinova sostojba da odrùva
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Kata Martinova 10. Grady RW., Berdo
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Vladimir âdikovski The computer th
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Vladimir âdikovski 5. Should peopl
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Nadica Ristoska Bojkovska Istorijat
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Nadica Ristoska Bojkovska � Virus
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Nadica Ristoska Bojkovska na CMV in
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Nadica Ristoska Bojkovska Takrolimu
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Nadica Ristoska Bojkovska Literatur
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Velibor Tasi] Hipourikemija e labor
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Velibor Tasi] Ovoj lek go zgolemuva
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Velibor Tasi] diabetes mellitus, ma
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Страна 188
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Emilija Vla[ki diagnostic investiga
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Emilija Vla[ki pnevmociti so difuzn
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Emilija Vla[ki dijagnosti~koto zna~
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Emilija Vla[ki na~eni promeni treba
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Katarina Stavri] na prisustvoto na
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Katarina Stavri] fagite i eozinofil
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Katarina Stavri] telite i decata do
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Страна 204
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Katerina Obo~ki What is the Practal
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Katerina Obo~ki Tret fakt: izloèno
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Katerina Obo~ki - izbegnuvawe na ek
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Katerina Obo~ki Zaklu~ok: Sekoga[ t
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