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Peptide-Based Active Immunotherapy in Cancer 129
90. Toes RE, Offringa R, Blom RJ, et al. Peptide vaccination can lead to enhanced tumor
growth through specific T-cell tolerance induction. Proc Natl Acad Sci U S A 1996;
93:7855–7860.
91. Webb S, Morris C, Sprent J. Extrathymic tolerance of mature T cells: clonal elimination
as a consequence of immunity. Cell 1990; 63:1249–1256.
92. Aichele P, Brduscha-Riem K, Zinkernagel RM, et al. T cell priming versus T cell
tolerance induced by synthetic peptides. J Exp Med 1995; 182:261–266.
93. Benichou G, Fedoseyeva E, Olson CA, et al. Disruption of the determinant hierarchy
on a self-MHC peptide: concomitant tolerance induction to the dominant determinant
and priming to the cryptic self-determinant. Int Immunol 1994; 6:131–138.
94. Sercarz EE, Lehmann PV, Ametani A, et al. Dominance and crypticity of T cell
antigenic determinants. Annu Rev Immunol 1993; 11:729–766.