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national-clinical-guidelines-for-stroke-fourth-edition

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National <strong>clinical</strong> guideline <strong>for</strong> <strong>stroke</strong><br />

1.10 Cost of <strong>stroke</strong> care<br />

Although implementation of this guideline may have cost implications, this document<br />

does not undertake a full cost-benefit analysis. Where we recognise that<br />

recommendations have significant resource implications, we have suggested that this<br />

needs to be considered locally.<br />

1.11 Licensing of drugs<br />

Recommendations about the use of specific drugs do not take into account whether the<br />

drug is licensed by the Medicines and Healthcare products Regulatory Agency (MHRA)<br />

<strong>for</strong> that particular use. It is up to the individual physician and their trust to decide<br />

whether to permit the unlicensed use of drugs in their <strong>for</strong>mulary.<br />

There are many situations where it may be appropriate to use medication which has not<br />

been licensed <strong>for</strong> specific situations (eg aspirin in acute ischaemic <strong>stroke</strong>). There are<br />

others where the rules of the licence are so strong that if broken it may result in the use<br />

of the therapy being legally withdrawn or funding discontinued if NICE guidance<br />

restricts its use.<br />

1.12 Updating the guideline<br />

It is recognised that research evidence changes continuously. The ICSWP will be<br />

reviewing the evidence on an ongoing basis. It is anticipated that a full review and fifth<br />

<strong>edition</strong> will be developed <strong>for</strong> 2016.<br />

1.13 Funding and conflicts of interest<br />

The guideline was developed as part of the Stroke Programme at the Clinical<br />

Effectiveness and Evaluation Unit, RCP. Funding <strong>for</strong> the programme was provided by a<br />

consortium from the Royal College of Physicians Trust Fund, the British Association of<br />

Stroke Physicians and the Stroke Association. Competing interests of the working party<br />

members were fully declared.<br />

10 © Royal College of Physicians 2012

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