national-clinical-guidelines-for-stroke-fourth-edition
national-clinical-guidelines-for-stroke-fourth-edition
national-clinical-guidelines-for-stroke-fourth-edition
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5 Secondary prevention<br />
5.0 Introduction<br />
This chapter covers secondary prevention. From the moment a person has an acute<br />
cerebrovascular event (of any sort), they are at increased risk of further events. The risk is<br />
substantial, 26% within 5 years of a first <strong>stroke</strong> and 39% by 10 years (Mohan et al 2011);<br />
there are additional risks of about the same magnitude <strong>for</strong> other vascular events (eg<br />
myocardial infarction). There are a few exceptions, <strong>for</strong> example patients who have a<br />
<strong>stroke</strong> secondary to arterial dissection.<br />
The risk of further <strong>stroke</strong> is highest early after <strong>stroke</strong> or TIA and may be as high as 5%<br />
within the first week and 20% within the first month. Appropriate secondary prevention<br />
should there<strong>for</strong>e be commenced as soon as possible, usually in the acute phase provided<br />
it is safe to do so. However, it is also vital that attention to secondary prevention should<br />
be continued throughout the recovery and rehabilitation phase and <strong>for</strong> the rest of the<br />
person’s life.<br />
Some of the recommendations in the acute phase, such as starting aspirin<br />
immediately after ischaemic <strong>stroke</strong>, are part of secondary prevention. This chapter<br />
assumes that all the recommendations made in chapter 4 have been implemented.<br />
The recommendations concerning the early reduction of risk are not repeated here,<br />
but it is essential that immediate treatments are carried out as part of secondary<br />
prevention.<br />
5.1 Identifying risk factors<br />
The risk of recurrent vascular events may vary significantly between individuals<br />
according to underlying pathology, comorbidities and lifestyle factors. This guideline<br />
applies to the vast majority of patients with TIA and <strong>stroke</strong>, including those not admitted<br />
to hospital, although some of the recommendations may not be appropriate <strong>for</strong> the small<br />
minority of patients with unusual <strong>stroke</strong> pathologies.<br />
5.1.1 Recommendations<br />
A Every patient who has had a <strong>stroke</strong> or TIA and in whom secondary preventation is<br />
appropriate should be investigated <strong>for</strong> risk factors as soon as possible and certainly<br />
within 1 week of onset.<br />
B For patients who have had an ischaemic <strong>stroke</strong> or TIA, the following risk factors<br />
should also be checked <strong>for</strong>:<br />
● atrial fibrillation and other arrhythmias<br />
● carotid artery stenosis (only <strong>for</strong> people likely to benefit from surgery)<br />
● structural and functional cardiac disease.<br />
© Royal College of Physicians 2012 61