Self-Assembly of Synthetic and Biological Polymeric Systems of ...

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4.3.1.- Relevant aspects I. For E12S10 dilute solutions, the coexistence of spherical micelles with vesicular structures has been observed. In addition, the spontaneous formation of vesicles by poly(oxystyrene)-poly(oxyethylene) block copolymers is reported for the first time, as confirmed by light scattering, polarized light microscopy, and transmission and cryo- scanning electron microscopy data. II. In dilute solution, the self-assembly of copolymer E10S10E10 leads to the formation of elongated micelles as supported by light scattering and transmission electron techniques. III. In the case of copolymer E137S18E137, typical spherical micelles are observed. Tube inversion and rheological measurements were used to define the sol- soft- and gel-hard boundaries of this copolymer. IV. E12S10 and E10S10E10 copolymers did not form gels in the concentration range analysed. However, only certain concentrations of copolymer E10S10E10 were analysed by rheometry. From experimental data, an upturn in the low-frequency range of the stress moduli was observed, denoting the existence of an emerging slow process, which was assigned to the formation of an elastic network. V. Block copolymers E12S10, E10S10E10 and E137S18E137 showed spontaneous adsorption at the air-water interface, which slowed down when the hydrophobicity of the molecule was increased. In contrast, at the chloroform/water interface no measurable effect is observed for copolymer E12S10 due to the slow diffusion of its chains to the interface in combination with a low bulk concentration; this slow diffusion is associated with the fact that chloroform is a good solvent for both E and S blocks. VI. Copolymer E137S18E137 displays an adsorption isotherm with the four classical regions representing the pancake, mushroom, brush and condensed states; the presence of a pseudo-plateau is attributed to the pancake-to-brush transition as E chains submerge into the aqueous sub-phase. On the other hand, for E12S10 and E10S10E10 copolymers only two regions are observed in their adsorption isotherms as a consequence of their low molecular weights, short S and E block lengths, and much larger S/E ratio. This involves the disappearance of the pseudo-plateau region due to the decrease in the fractional interfacial area occupied by EO segments. VII. According to AFM images, circular micelles are observed on Langmuir-Blodgett films of the copolymers obtained at two surface transfer pressures. A decrease in micelle size and an 124
increase in monolayer thickness are observed with increases in transfer pressure. Aggregation numbers derived from AFM images increase with the increase of the S weight fraction at a certain deposition pressure, which can be a consequence of stronger attractive interactions between the S blocks to avoid contact with the solvent. 125
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Grupo de Física de Coloides y Pol
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Agradecimientos A mi Familia A mi P
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v List of papers I. Self-assembly p
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2.3 2.4 2.5 2.6 2.7 2.8 2.9 2.10 2.
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5.4 5.5 5.3.2 5.5.1 Chapter 6 Kinet
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amiloides de la proteína albúmina
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vesiculares son el resultado de la
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origina debido a condiciones ambien
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con las fibras vecinas más cercana
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Abstract In the present work, we in
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[Au]/[protein] molar ratio and numb
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synthetic polymers are obtained fro
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On the other hand, in terms of chem
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Additionally, to obtain a better kn
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therefore, characteristic of solid
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presence of electrostatic charge in
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Contents 2.1 2.2 2.3 2.4 2.5 2.6 2.
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where w is the meniscus’ weight d
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that they exert little force one on
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This oscillating dipole acts as an
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(APD) and its associated optics (pi
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where r is the distance of the dipo
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When , the former equation can be s
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autocorrelation function (ACF). In
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and, therefore, . The autocorrelati
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A transmission electron microscope
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2.5.- Atomic force microscopy (AFM)
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ecause of the energy loss in the ex
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Figure 2.15. Schematic representati
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ackbone of proteins. Since proteins
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According to classical mechanics, t
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chemical composition, configuration
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2.9.1.- Viscoelasticity Many materi
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where is the total strain rate, whi
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Using equations 2.40 and 2.41 in eq
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scattering process that incoming X-
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maximum intensity of the peak, Imax
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translation of the reciprocal latti
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For a single crystal, the chance to
Page 87 and 88: excitation; namely, a valance elect
Page 89 and 90: Figure 2.27. Distinction between si
Page 91 and 92: microscope, there are two polarized
Page 93 and 94: In particular, we use SQUID to meas
Page 95 and 96: are aligned by means of an external
Page 97 and 98: on the digital profile of a drop im
Page 99 and 100: Laser confocal microscopy. Confocal
Page 101 and 102: Fluorescence spectroscopy. Fluoresc
Page 103: Superconducting quantum interferenc
Page 106 and 107: temperatures, the chains are mixed
Page 108 and 109: e detected by a given method. Therm
Page 110 and 111: subsequently, of their thermodynami
Page 112 and 113: a) O b) H 2C CH 2 O H 2C CH Figure
Page 115: Contents 4.1 4.2 4.3 4.3.1 CHAPTER
Page 118 and 119: 7108 Langmuir, Vol. 24, No. 14, 200
Page 128 and 129: 15704 J. Phys. Chem. C, Vol. 114, N
Page 141 and 142: Contents 5.1 5.2 5.3 5.4 5.5 5.1.1
Page 143 and 144: acids whose lateral side chains cha
Page 145 and 146: adjacent segments of an antiparalle
Page 147 and 148: 5.2.1.- Unfolded state Over the las
Page 149 and 150: 5.2.4.- Energy landscape: protein a
Page 151 and 152: molecular medicine viewpoint, prote
Page 153 and 154: shows the typical nucleation-depend
Page 155 and 156: the energy landscape of the aggrega
Page 157: exposed loop region. The secondary
Page 161 and 162: Biophysical Journal Volume 96 March
Page 163 and 164: Fibrillation Pathway of HSA 2355 q
Page 165 and 166: Fibrillation Pathway of HSA 2357 mo
Page 167 and 168: Fibrillation Pathway of HSA 2359 in
Page 169 and 170: Fibrillation Pathway of HSA 2361 Fu
Page 171 and 172: Fibrillation Pathway of HSA 2363 FI
Page 173 and 174: Fibrillation Pathway of HSA 2365 Wh
Page 175 and 176: Fibrillation Pathway of HSA 2367 of
Page 177 and 178: Fibrillation Pathway of HSA 2369 17
Page 179 and 180: Influence of Electrostatic Interact
Page 181 and 182: Fibrillation Process of Human Serum
Page 187: Fibrillation Process of Human Serum
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12392 J. Phys. Chem. B, Vol. 113, N
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5 10 15 20 25 30 35 40 45 Soft Matt
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5 10 15 20 25 r h,app = kT/(6πηD
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5 10 15 20 25 30 35 40 45 50 below,
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5 10 15 20 25 30 55 Figure 3: Selec
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10 15 Soft Matter Cite this: DOI: 1
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5 10 15 Soft Matter Cite this: DOI:
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5 65. L. A. Sikkink, M. Ramirez-Alv
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ions would interact electrostatical
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pubs.acs.org/JPCL Figure 3. (a) Tim
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(54) Almeida, N. L.; Oliveira, C. L
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netospirillum magneticum strain AMB
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One-Dimensional Magnetic Nanowires
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temperatures, and solvent polarity.
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Conclusions The work has two parts:
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equire a highly organized and unsta
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References 1. Hiemenz, Paul C. Poly
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33. Wang, Z. L. HANDBOOK OF MICROSC
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67. Polymers Get Organized. Bucknal
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94. Are there Pathways for Protein
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123. Designing conditions for in vi
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151. SERS-based diagnosis and biode
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