19.07.2013 Views

Alcohol misuse: tackling the UK epidemic - London

Alcohol misuse: tackling the UK epidemic - London

Alcohol misuse: tackling the UK epidemic - London

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

BMA Board of Science<br />

“”<br />

One image that sticks in my mind was <strong>the</strong> patient who had such severe memory<br />

problems secondary to alcohol that he came out of his room every few minutes<br />

asking where his jacket was, not realising that he was doing this about 15 times per<br />

hour – and what I also remember is <strong>the</strong> sustained patience of <strong>the</strong> nursing staff!<br />

BMA member<br />

The evidence that alcohol consumption is a contributory cause of a number of cancers has<br />

58, 59<br />

streng<strong>the</strong>ned in recent years. A 2007 review concluded that <strong>the</strong>re is convincing evidence that<br />

alcoholic drinks are a contributory cause of cancers of <strong>the</strong> mouth, pharynx, and larynx,<br />

oesophagus, colorectum (men), and breast, and a probable cause of colorectal cancer in women<br />

and of liver cancer. 59<br />

The review also concluded that <strong>the</strong>re is no safe threshold below which no<br />

effect on cancer risk is observed. 59<br />

The adverse effects of alcohol on health outlined in Box 2 are<br />

most notable in individuals who are alcohol dependent. <strong>Alcohol</strong> dependence syndrome is strongly<br />

associated with neurologic impairment, cardiovascular disease, liver disease, malignant neoplasms,<br />

and an increased risk of injury. 37<br />

While <strong>the</strong> majority of effects from alcohol are detrimental to health, consumption at moderate<br />

levels or below is associated with a lower risk of CHD, ischaemic stroke and diabetes mellitus<br />

55, 57, 58, 60-62<br />

compared to individuals who abstain from alcohol. These positive effects on <strong>the</strong> risk of<br />

CHD appear to be confined to males over <strong>the</strong> age of 45 years and females past <strong>the</strong> menopause. 63<br />

As consumption increases above moderate levels, however, <strong>the</strong> risk relation reverses.<br />

“”<br />

Unfortunately, us doctors, journalists and politicians have supported <strong>the</strong> concept<br />

that alcohol is good for you (raises HDL cholesterol, <strong>the</strong> good cholesterol), but of<br />

course not for all, and only in small amounts.<br />

BMA member<br />

<strong>Alcohol</strong> <strong>misuse</strong>: <strong>tackling</strong> <strong>the</strong> <strong>UK</strong> <strong>epidemic</strong> 29

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!