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Soins maternels intensifs (Maternal Intensive Care) en Belgique - KCE

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Schatz et al ( 15<br />

bis<br />

kCE Reports 94 <strong>Maternal</strong> <strong>Int<strong>en</strong>sive</strong> <strong>Care</strong> in Belgium 109<br />

USA 1739 pregnant<br />

asthmatic<br />

pati<strong>en</strong>ts, < 26<br />

weeks gestation<br />

all births in basic and<br />

compreh<strong>en</strong>sive EmOC facilities,<br />

met need for EmOC: proportion of<br />

wom<strong>en</strong> estimated to have<br />

complications who are treated in<br />

EmOC facilities, caesarean section<br />

as perc<strong>en</strong>tage of all births in the<br />

population and case fatality rate in<br />

EmOC. All these indicators are<br />

compared to the minimum<br />

acceptable level recomm<strong>en</strong>ded by<br />

WHO/UNICEF/UNFPA.<br />

Prospective observational cohort<br />

study from 1994-1999 in 16<br />

<strong>Maternal</strong>-Fetal Medicine Units. This<br />

study evaluates the relationship<br />

betwe<strong>en</strong> asthma severity<br />

classification (1993) during<br />

pregnancy and gestational asthma<br />

exacerbations. 873 pregnant<br />

pati<strong>en</strong>ts with mild asthma, 814<br />

moderate & 52 severe asthma<br />

pati<strong>en</strong>ts were included. Participants<br />

were excluded for known multiple<br />

gestation, intrauterine fetal demise,<br />

major cong<strong>en</strong>ital abnormalities,<br />

active pulmonary disease other<br />

than asthma, inability to schedule<br />

an ultrasound for gestational age<br />

confirmation, or gestational age<br />

greater than 25 weeks and 6 days<br />

at intake.<br />

All obstetric pati<strong>en</strong>ts were asked<br />

for physician diagnosed asthma.<br />

Information regarding symptom<br />

frequ<strong>en</strong>cy, asthma medication use,<br />

Prospective<br />

observational<br />

cohort study<br />

combined case-fatality rate in the<br />

basic/compreh<strong>en</strong>sive EmOC facilities was<br />

1.7%. Major obstetric complications<br />

contributed to 85.7% of maternal deaths, and<br />

pre-eclampsia/eclampsia was the most<br />

common cause.<br />

CONCLUSION: It can be concluded that<br />

all the process indicators, except proportion<br />

of deliveries in the EmOC facilities, were<br />

below the acceptable level. Certain priority<br />

measures, such as making facilities fully<br />

functional, effective referral and monitoring<br />

system, skill-based training, etc., are to be<br />

emphasized to improve the situation.<br />

OBJECTIVE: The objective of this study<br />

was to evaluate the relationship betwe<strong>en</strong><br />

asthma severity classification during<br />

pregnancy and gestational asthma<br />

exacerbations.<br />

RESULTS: Initial asthma classification (mild,<br />

moderate, or severe) was significantly related<br />

to subsequ<strong>en</strong>t asthma morbidity during<br />

pregnancy (hospitalizations, unscheduled<br />

visits, corticosteroid requirem<strong>en</strong>ts, and<br />

asthma symptoms during labor and delivery).<br />

Exacerbations during pregnancy occurred in<br />

12.6% of pati<strong>en</strong>ts initially classified as mild,<br />

25.7% of pati<strong>en</strong>ts classified as moderate, and<br />

51.9% of pati<strong>en</strong>ts classified as severe (P <<br />

.001). Asthma morbidity was similar, whether<br />

pati<strong>en</strong>ts were classified as moderate or<br />

severe by symptoms and spirometry or by<br />

medication requirem<strong>en</strong>t. Thirty perc<strong>en</strong>t of<br />

initially mild pati<strong>en</strong>ts were reclassified as<br />

moderate-severe during pregnancy, and 23%<br />

of the initially moderate-severe pati<strong>en</strong>ts were<br />

reclassified as mild later in pregnancy; asthma<br />

morbidity in these pati<strong>en</strong>ts changed<br />

1+<br />

2+<br />

3+<br />

4+/-<br />

5+<br />

6+/-<br />

7?<br />

8+<br />

9+/-<br />

10-<br />

Score:ok<br />

3

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