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Soins maternels intensifs (Maternal Intensive Care) en Belgique - KCE

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Mirghani, H.,<br />

Hamed, M. &<br />

Weerasinghe, D.<br />

(2004)<br />

kCE Reports 94 <strong>Maternal</strong> <strong>Int<strong>en</strong>sive</strong> <strong>Care</strong> in Belgium 125<br />

16 United Arab<br />

Emirates<br />

60 obstetric<br />

pati<strong>en</strong>ts<br />

admitted to<br />

the ICU<br />

pregnancy were noted. Acute<br />

disorders leading to ICU admission<br />

were classified into medical and<br />

obstetric.<br />

Outcome variables studied were<br />

maternal and fetal mortality rate and<br />

l<strong>en</strong>gth of ICU stay<br />

A retrospective tertiary c<strong>en</strong>tre based<br />

review of records and ICU sheets of<br />

all obstetric pati<strong>en</strong>ts admitted to the<br />

ICU at the Al-Ain teaching hospital,<br />

betwe<strong>en</strong> 1997 and 2002.<br />

Data extracted included demographic<br />

data, diagnosis and reason for<br />

Retrospective<br />

tertiary<br />

c<strong>en</strong>tre based<br />

analysis of<br />

obstetric<br />

admissions to<br />

the ICU<br />

138 with single organ failure and 152 with multiple organ<br />

failure. Ninety-eight wom<strong>en</strong> died (mortality rate 21.6%).<br />

Mortality was comparable in antepartum (n =216) and<br />

postpartum (n =247) admissions but increased with<br />

increasing number of organs affected. There were 236<br />

fetal deaths (52%), of which 104 occurred before<br />

hospital admission. Median APACHE II score was 16<br />

(interquartile range, 10–24), and standardized mortality<br />

ratio (observed deaths/predicted deaths) was 0.78.<br />

Compared with pregnant pati<strong>en</strong>ts admitted with<br />

obstetric disorders (n =313), those with medical diseases<br />

(n=140) had significantly lower APACHE II scores<br />

(median 14 vs. 17) but higher observed mortality rate<br />

(28.6% vs. 18.5%; odds ratio, 1.76; 95% confid<strong>en</strong>ce<br />

interval, 1.08 –2.87) and standardized mortality ratio<br />

(1.09 vs. 0.66). On multivariate analysis, increased<br />

mortality rate was associated with acute cardiovascular<br />

(odds ratio, 5.8), nervous system (odds ratio, 4.73) and<br />

respiratory (odds ratio, 12.9) failure, disseminated<br />

intravascular coagulation (odds ratio, 2.4), viral hepatitis<br />

(odds ratio, 5.8), intracranial hemorrhage<br />

(odds ratio, 5.4), abs<strong>en</strong>ce of pr<strong>en</strong>atal care (odds ratio,<br />

1.94), and >24 hrs interval betwe<strong>en</strong> onset of acute<br />

symptoms and int<strong>en</strong>sive care unit admission (odds ratio,<br />

2.3).<br />

CONCLUSIONS: Multiple organ failure is common in<br />

obstetric pati<strong>en</strong>ts; mortality rate increases with<br />

increasing organ failure. APACHE II scores overpredict<br />

mortality rate. Standardized mortality ratio is lower in<br />

obstetric disorders than in medical disorders. Lack of<br />

pr<strong>en</strong>atal care and delay in int<strong>en</strong>sive care unit referral<br />

adversely affect outcome and are easily prev<strong>en</strong>table.<br />

OBJECTIVE: this study aimed to id<strong>en</strong>tify indications,<br />

course and outcome of pregnancy-related admissions to<br />

the int<strong>en</strong>sive care unit at Al-Ain hospital.<br />

RESULTS: A total of 60 pati<strong>en</strong>ts were admitted during<br />

the six years. The frequ<strong>en</strong>cy of admission was 2.6 per<br />

1000 deliveries and obstetric pati<strong>en</strong>ts repres<strong>en</strong>ted 2.4%<br />

of all ICU admissions. Admission was planned in 11<br />

10?<br />

Score:+/-<br />

1+/-<br />

2+<br />

3+<br />

4+/-<br />

5?<br />

6?<br />

7+/-<br />

3

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