Prospectus | 08/09 - Psychology and Neuroscience - Maastricht ...
Prospectus | 08/09 - Psychology and Neuroscience - Maastricht ...
Prospectus | 08/09 - Psychology and Neuroscience - Maastricht ...
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Chapter 3 - Specialization Fundamental <strong>Neuroscience</strong><br />
Alex<strong>and</strong>er Sack, Cognitive <strong>Neuroscience</strong> (FPN), Phone 38 84267, 40 Universiteitssingel<br />
East, Room 4.765, E-mail: a.sack@psychology.unimaas.nl;<br />
Jos Prickaerts, Neuropsychology & Psychopharmacology (FPN), Phone 38 81026,<br />
40 Universiteitssingel East, Room 2.737, E-mail: j.prickaerts@psychology.unimaas.nl<br />
Description of the Course<br />
This lecture course, attended by all first year students, is designed to highlight<br />
selected research topics from the perspectives of cognitive neuroscience, fundamental<br />
neuroscience, neuropsychology <strong>and</strong> psychopathology. The aim is to illustrate how the<br />
distinct but inter-related approaches to questions in the field of brain <strong>and</strong> behaviour<br />
can enrich our underst<strong>and</strong>ing of underlying mechanisms as well as cognitive,<br />
emotional <strong>and</strong> behavioural outcomes in health <strong>and</strong> disorder.<br />
49<br />
Instructional Approach<br />
A series of four lectures for each of two broad themes. Faculty members from each of<br />
the four specializations will present lectures in successive weeks.<br />
Required readings, assigned by each lecturer, will be made available prior to the first<br />
meeting of a new theme.<br />
Form of Assessment<br />
Following each series of four lectures, an open book exam will be given, covering<br />
material from all of the assigned readings <strong>and</strong> lectures for that theme. The final pass/<br />
fail score is based on the average grade obtained on the two exams.<br />
3.2 Core courses<br />
| 411FN Advanced Molecular Biology Techniques – 5 credits<br />
Coordinator: Pilar Martínez - Martínez, Psychiatry & Neuropsychology (FHML),<br />
Phone 38 81263, 50 Universiteitssingel, Room 1.136, E-mail: p.martinez@np.unimaas.nl<br />
Description of the Course<br />
This course in molecular biology techniques is designed to provide students with a<br />
conceptual <strong>and</strong> practical underst<strong>and</strong>ing of several of the most advanced techniques in<br />
molecular neuroscience. In this course, the laboratory portion will include topics such<br />
as: the use of small interfering RNAs (siRNA) for regulating the expression of specific<br />
genes in neurons; practical exercises in gene delivery systems including mammalian<br />
cell transfection protocols <strong>and</strong> gene electroporation techniques for targeted gene<br />
transfer in vivo; an introduction to overall strategies, cloning, whole genome expression<br />
analyses using DNA microarray technologies; quantitative real time RT-PCR analyses<br />
from small numbers of cells (probes design, RNA purification, PCR optimization,<br />
interpretation of results). Students will also be introduced to bioinformatics <strong>and</strong> a wide<br />
range of internet resources which are available to molecular neuroscientists.