Annual Meeting Program - Society of Toxicology

Society of Toxicology 2008
Program Description (Continued)
Abstract #
Monday Morning, March 17
9:30 AM to 12:30 PM
Exhibit Hall
POSTER SESSION: CHEMICAL AND BIOLOGICAL WEAPONS
Chairperson(s): Alan Brimfield, USAMRICD, Aberdeen Proving Ground,
MD and Heather Floyd, U.S. EPA, Research Triangle Park, NC.
Displayed: 9:30 AM–12:30 PM
Attended: 9:30 AM –11:00 AM
#125 Poster Board Number.......................................203
KINETICS OF SUBCUTANEOUS EXPOSURE
TO SUB-LETHAL VX, GF AND GB DOSES
IN GUINEA PIG. C. E. Whalley 1 , L. A.
Lumley 2 , J. M. McGuire 1 , C. Robison 2 , T. Ward 2 ,
B. Somsamayvong 2 , E. M. Jakubowski 1 , R. J.
Mioduszewski 1 , T. M. Shih 2 and S. A. Thomson 1 .
1
ECBC, APG, MD and 2 USAMRICD, APG, MD.
#126 Poster Board Number.......................................204
POST-EXPOSURE PROTECTION AGAINST
SOMAN-INDUCED LETHALITY WITHOUT
CARBAMATE PRETREATMENT IN GUINEA
PIGS. S. DeBus, D. Spriggs and F. Chang.
USAMRICD, Edgewood, MD. Sponsor: W. Smith.
#127 Poster Board Number.......................................205
PHYSIOLOGICALLY-BASED MODELING
OF NEUROTHERAPEUTICS. E. A. Merrill,
P. J. Robinson and J. M. Gearhart. AFRL, Applied
Biotechnology Branch, HJF, Wright-Patterson AFB,
OH.
#128 Poster Board Number.......................................206
SIMULATION OF VX EXPOSURE
IN MULTIPLE SPECIES BY
MEANS OF A PHYSIOLOGICALLY
BASED PHARMACOKINETIC/
PHARMACODYNAMIC MODEL (PBPK/PD).
J. Gearhart 1 , P. Robinson 1 , C. Whalley 2 , J. McGuire 2 ,
R. Evans 2 , S. Hulet 2 , C. Byers 2 and E. Jakubowski 2 .
1
AFRL/HEPB, Henry M. Jackson Foundation,
Wright-Patterson Air Force Base, OH and 2 U.S.
Army ECBC, Edgewood, MD.
#129 Poster Board Number.......................................207
A PHYSIOLOGICALLY-BASED
DEPOSITION, CLEARANCE, AND
SYSTEMIC BIOKINETIC MODEL OF
INHALED BACILLUS ANTHRACIS SPORES.
E. Hack 1 , B. Gutting 3 , P. Robinson 1 , T. Nichols 2 , G.
Andrews 3 and J. Gearhart 1 . 1 HJF AFRL, Wright-
Patterson AFB, OH, 2 U.S. EPA, Cincinnati, OH and
3
NAVSEA, Dahlgren, VA.
#130 Poster Board Number.......................................208
COMPARATIVE HEMATOTOXICITY
OF HEXAHYDRO-1, 3, 5-TRINITRO-1,
3, 5-TRIAZINE (RDX) VS. MONO- AND
TRI-NITROSO ENVIRONMENTAL
DEGRADATION PRODUCTS MNX AND TNX.
M. S. Wilbanks 1 , S. Reeves 1 , L. Escalon 2 , E. J.
Perkins 3 and S. A. Meyer 1 . 1 Toxicology, University
Louisiana-Monroe, Monroe, LA, 2 SpecPro,
Vicksburg, MS and 3 ERDC, U.S. Army Corps of
Engineers, Vicksburg, MS.
Abstract #
#131 Poster Board Number.......................................209
KINEMATIC EVALUATION OF MOTOR
IMPAIRMENT AND RECOVERY OF
FUNCTION FOLLOWING SOMAN
EXPOSURE IN A RAT MODEL. L. Lumley, C.
Robison, S. Estes, S. Parylak, J. Kraft, T. Ward, K.
Kamberger, S. Johnson and T. Shih. USAMRICD,
Aberdeen Proving Ground, MD.
#132 Poster Board Number.......................................210
PREDICTABILITY AND RELIABILITY
OF THE UP-AND-DOWN METHOD
FOR DETERMINING LD50 VALUES
FOR CHEMICALS WITH STEEP DOSE-
RESPONSE CURVES: AN ANALYSIS OF
INTRAVENOUS VX TOXICITY IN THE
GOTTINGEN MINIPIG. S. W. Hulet, D. R.
Sommerville, B. J. Benton, J. A. Scotto, D. C.
Burnett, R. J. Mioduszewski and S. A. Thomson.
Toxicology, U.S. Army ECBC, Aberdeen Proving
Grounds, MD.
#133 Poster Board Number.......................................211
EFFICACY OF NOVEL PYRIDINIUM
OXIMES TO REACTIVATE RAT
BRAIN AND RED BLOOD CELL
ACETYLCHOLINESTERASE INHIBITED
BY ORGANOPHOSPHATES. E. C. Meek 1 , H.
W. Chambers 2 , J. S. Manion 1 and J. E. Chambers 1 .
1
Center for Environmental Health Sciences,
Mississippi State University, Mississippi State, MS
and 2 Department of Entomology, Mississippi State
University, Mississippi State, MS.
#134 Poster Board Number.......................................212
A SULFUR MUSTARD AND THERMAL
SUPERFICIAL DERMAL INJURY PIG
MODEL. F. M. Reid 1 , R. C. Kiser 1 , W. E. Hart 1 ,
E. E. McGuinness 1 , J. Mann 1 and J. S. Graham 2 .
1
Biomedical Research Center, Battelle, West
Jefferson, OH and 2 Medical Toxicology Branch,
U.S. Army Medical Research Institute of Chemical
Defense, APG, MD.
#135 Poster Board Number.......................................213
MECHANISM OF INHIBITION OF
THIOREDOXIN REDUCTASE IN LUNG
EPITHELIAL CELLS BY THE VESICANT
2-CHLOROETHYL ETHYL SULFIDE. Y.
Jan 1 , J. P. Gray 1 , A. T. Black 1 , D. R. Gerecke 1 ,
R. P. Casillas 2 , D. L. Laskin 1 and J. D. Laskin 3 .
1
Pharmacology & Toxicology, Rutgers University,
Piscataway, NJ, 2 Biomedical Science and
Technology, Battelle Biomedical Research Center,
Columbus, OH and 3 Environmental & Occupational
Medicine, UMDNJ-Robert Wood Johnson Medical
School, Piscataway, NJ.
#136 Poster Board Number.......................................214
RADIATION PROTECTION AGAINST
EARLY AND LATE EFFECTS OF IONIZING
RADIATION BY GENISTEIN. M. R. Landauer 1 ,
M. Barshishat-Kupper 2 , S. R. Mog 1 , E. A. McCart 1 ,
P. G. Prasanna 1 , T. A. Davis 3 and R. M. Day 2 . 1 Armed
Forces Radiobiology Research Institute, Bethesda,
MD, 2 Uniformed Services University, Bethesda, MD
and 3 Naval Medical Research Center, Bethesda, MD.
Monday
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