Annual Meeting Program - Society of Toxicology

47 th Annual Meeting & ToxExpo
Program Description (Continued)
Wednesday
Abstract # Abstract #
#1949 Poster Board Number.......................................647
MICE THAT DO NOT EXPRESS
GLUTATHIONE REDUCTASE ARE MORE
SUSCEPTIBLE THAN ARE WILD TYPE
MICE TO INFECTION WITH GROUP B
STREPTOCOCCUS. M. M. Ralston 1 , K. D.
Bongiovanni 1 , A. L. Jones 2 and C. V. Smith 1 . 1 Seattle
Children’s Hospital Research Institute, Center
for Developmental Therapeutics, Seattle, WA and
2
Center for Childhood Infections and Prematurity,
Seattle Children’s Hospital Research Institute,
Seattle, WA.
#1950 Poster Board Number.......................................648
EXPRESSION AND FUNCTION OF
ALDEHYDE DEHYDROGENASE 3B1.
S. A. Marchitti 1 , D. J. Orlicky 2 and V. Vasiliou 1 .
1
Pharmaceutical Sciences, University of Colorado
Health Sciences Center, Denver, CO and 2 Pathology,
University of Colorado Health Sciences Center at
Fitzsimmons, Aurora, CO.
#1951 Poster Board Number.......................................649
ALDH7A1 IS A NOVEL ALDH THAT
PROTECTS AGAINST OXIDATIVE
DAMAGE. C. Brocker 1 , M. Cantore 1 , A. Pappa 1 , N.
Lassen 1 , T. Estey 1 , S. A. Marchitti 1 , T. Chavakis 2 and
V. Vasiliou 1 . 1 Pharmaceutical Sciences, University of
Colorado Health Sciences Center, Denver, CO and
2
Experimental Immunology Branch, National Cancer
Institute, National Institutes of Health, Bethesda,
MD.
#1952 Poster Board Number.......................................650
ORAL ADMINISTRATION OF
POLAPREZINC, AN ANTI-ULCER DRUG,
PROTECTS MICE AGAINST ENDOTOXIN
SHOCK. T. Matsura 1 , C. Moriyama 1 , A. Yamashita 1 ,
H. Morikawa 1 , T. Nishida 1 , S. Ohata 1 , C. Kusumoto 1 ,
J. Nakada 2 and K. Yamada 1 . 1 Medical Biochemistry,
Tottori University Faculty of Medicine, Yonago,
Tottori-ken, Japan and 2 Anesthesiology, Aichi Cancer
Center Hospital, Nagoya, Japan. Sponsor: V. Kagan.
#1953 Poster Board Number.......................................651
THE ROLE OF REACTIVE OXYGEN
SPECIES(ROS)IN AIRWAY HYPER-
RESPONSIVENESS:THE EFFECTS
OF 2-CYANO-3, 12-DIOXOOLEANA-1,
9(11)-DIENE-28-OIC ACID(CDDO). D.
Hochman 1 , D. Nanyes 3 , S. Schultz 2 and E. Brooks 2 .
1
Experimental Pathology, University of Texas
Medical Branch, Galveston, TX, 2 Pediatrics,
University of Texas Medical Branch, Galveston, TX
and 3 The University of Houston, Houston, TX.
#1954 Poster Board Number.......................................652
DISTINCT ROLES OF REACTIVE OXYGEN
AND NITROGEN INTERMEDIATES IN
ACUTE LUNG INJURY INDUCED BY
OZONE AND BLEOMYCIN. A. M. Groves 1 , J.
D. Laskin 2 , A. J. Gow 1 , C. Guo 1 and D. L. Laskin 1 .
1
Rutgers University, Piscataway, NJ and 2 UMDNJ-
RW Johnson Med Sch, Piscataway, NJ.
#1955 Poster Board Number.......................................653
DISRUPTION OF ANTIOXIDANT DEFENSE
AND DNA REPAIR SYSTEMS DURING
2-ACETYLAMINOFLUORENE-INDUCED
HEPATOCARCINOGENESIS IN RATS. T. V.
Bagnyukova 1 , C. L. Powell 2 , B. Montgomery 1 , F. A.
Beland 1 and I. P. Pogribny 1 . 1 Division of Biochemical
Toxicology, FDA-National Center for Toxicological
Research, Jefferson, AR and 2 Department of
Genetics, University of North Carolina, Chapel Hill,
NC.
#1956 Poster Board Number.......................................654
670 NM PHOTOBIOMODULATION
NORMALIZES ANTIOXIDANT
ENZYME ACTIVITIES SUPPRESSED IN
STREPTOZOTOCIN-INDUCED DIABETIC
RAT. J. Lim 1 , R. A. Sanders 2 , R. Wilson 3 , A. C.
Snyder 3 , S. Gopalakrishnan 3 , J. T. Eells 3 , J. B.
Watkins III 2 and D. S. Henshel 1 . 1 SPEA, Indiana
University, Bloomington, IN, 2 Medical Sciences,
Indiana University, Bloomington, IN and 3 Health
Sciences, University of Wisconsin-Milwaukee,
Milwaukee, WI.
#1957 Poster Board Number.......................................655
SUBCHRONIC TOXICITY OF INHALED
TOLUENE IN RATS: OXIDATIVE STRESS
MARKERS IN BRAIN. D. A. Moore-Smith 1,3 ,
J. H. Richards 2 , T. E. Samsam 1 , P. Evansky 2 , P. J.
Bushnell 1 and P. R. Kodavanti 1 . 1 Neurotoxicology
Division, U.S. EPA, RTP, NC, 2 Experimental
Toxicology Division, U.S. EPA, RTP, NC and
3
Department of Biology, Livingstone College,
Salisbury, NC.
#1958 Poster Board Number.......................................656
SUPPRESSION OF DFP-INDUCED
OXIDATIVE INJURY AND DENDRITIC
DAMAGE IN RAT BRAIN. D. Milatovic 1 , S.
Zaja-Milatovic 1 , R. C. Gupta 2 and M. Aschner 1 .
1
Pediatrics, Vanderbilt University, Nashville, TN
and 2 Breathitt Vet. Center, Murray State University,
Hopkinsville, KY.
#1959 Poster Board Number.......................................657
A BIOTIN-HYDROXYLAMINE LABELING
METHOD FOR THE DETECTION
OF OXIDIZED PROTEINS USING
WESTERN BLOT ANALYSIS AND MASS
SPECTROMETRY. W. Chung, C. L. Miranda and
C. S. Maier. Chemistry, Oregon State University,
Corvallis, OR.
#1960 Poster Board Number.......................................658
A UPLC/MS/MS PROCEDURE FOR THE
DETERMINATION OF ISOPROSTANES IN
HUMAN SERUM. A. R. Molinelli 1 , T. J. Laha 1 ,
M. J. Edenfield 1 and S. M. Sadrzadeh 2 . 1 Laboratory
Medicine, University of Washington, Seattle, WA and
2
Unaffiliated Consultant, Seattle, WA.
#1961 Poster Board Number.......................................659
PHOSPHOLIPID PEROXIDATION
BIOMARKERS OF ALZHEIMER’S DISEASE
IN THE BRAIN: SELECTIVE OXIDATION
OF PHOSPHATIDYLSERINE. V. A. Tyurin 1,2 ,
Q. Zhao 1,2 , A. Mnuskin 1,2 , R. L. Hamilton 3 , S. T.
DeKosky 4 , W. F. Reynolds 5 and V. E. Kagan 1,2 . 1 EOH,
University of Pittsburgh, Pittsburgh, PA, 2 CFRAH,
University of Pittsburgh, Pittsburgh, PA, 3 Pathology,
University of Pittsburgh, Pittsburgh, PA, 4 Neurology,
University of Pittsburgh, Pittsburgh, PA and 5 Sidney
Kimmel Cancer Center, San Diego, CA.
256
SOT’s 47 th Annual Meeting