Annual Meeting Program - Society of Toxicology

47 th Annual Meeting & ToxExpo
Monday
Program Description (Continued)
Abstract # Abstract #
#220 Poster Board Number.......................................425
INFLAMMATION-MEDIATED LIVER
INJURY IN RATS COTREATED WITH
SULINDAC AND LIPOPOLYSACCHARIDE.
W. Zou 1 , S. S. Devi 1 , H. S. Younis 2 , R. A. Roth 1 and P.
E. Ganey 1 . 1 Michigan State university, East Lansing,
MI and 2 Pfizer Global Research and Development,
San Diego, CA.
#221 Poster Board Number.......................................426
MODIFIED ALCOHOL LIQUID DIET
MODEL FOR LIVER INJURY IN MICE. B.
Bradford 1 , O. Kosyk 1 , H. Kono 2 , S. Shymonyak 1 , P.
Ross 1 and I. Rusyn 1 . 1 Environmental Sciences and
Engineering, UNC Chapel Hill, Chapel Hill, NC and
2
Surgery, U. Yamanashi, Yamanashi, Japan.
#222 Poster Board Number.......................................427
A NOVEL “PATIENT-LIKE” MODEL OF
CHOLANGIOCARCINOMA PROGRESSION
BASED ON BILE DUCT INOCULATION OF
TRANSFORMED RAT CHOLANGIOCYTES
OVEREXPRESSING ERBB2. A. E. Sirica, D.
J. Campbell and Z. Zhang. Pathology, Virginia
Commonwealth University School of Medicine,
Richmond, VA.
#223 Poster Board Number.......................................428
MONITORING A MOUSE WHICH
EXPRESSES A YELLOW FLUORESCENT
PROTEIN IN MONOCYTES WITH
INTRAVITAL MICROSCOPY. T. Kampfrath, J.
Anderson, Q. Sun, S. Parthasarathy, M. Ostrowski
and S. Rajagopalan. Ohio State University,
Columbus, OH.
#224 Poster Board Number.......................................429
LIVER-SELECTIVE EXPRESSION OF
FUNCTIONAL HUMAN ARYLAMINE
ACETYLTRANSFERASE NAT2 IN
TRANSGENIC MICE. K. S. Sugamori, D.
Brenneman and D. M. Grant. Pharmacology and
Toxicology, University of Toronto, Toronto, ON,
Canada.
#225 Poster Board Number.......................................430
TOXICOLOGICAL RESPONSES TO 1,
2-DICHLORO-4-NITROBENZENE IN
GLUTATHIONE S-TRANSFERASE M1
KNOCKOUT MICE. W. Takasaki, S. Arakawa, K.
Fujimoto, T. Maejima, Y. Shibaya, T. Yamaguchi, H.
Miida, R. Kawai, Y. Ando, T. Yamoto and S. Manabe.
Medicinal Safety Res Labs, Daiichi-Sankyo Co.,
Ltd., Fukuroi, Shizuoka, Japan.
#226 Poster Board Number.......................................431
A NOVEL TRANSGENIC MOUSE MODEL
EXPRESSING A HUMAN ENZYME FOR
REPAIR OF OXIDATIVE DNA DAMAGE. S. L.
Ondovcik 1 , T. J. Preston 1 , S. K. Ho 1 , J. T. Henderson 1 ,
K. Lam 2 and P. G. Wells 1,2 . 1 Pharmaceutical Sciences,
University of Toronto, Toronto, ON, Canada and
2
Pharmacology and Toxicology, University of
Toronto, Toronto, ON, Canada.
#227 Poster Board Number.......................................432
CARCINOGENIC COMPARATIVE STUDY
ON CB6F1 TG RASH2 MICE PRODUCED BY
TWO BREEDING FACILITIES. K. Urano, K.
Machida, M. Yoshimura, K. Kikuchi, T. Nomura and
T. Usui. Central Institute for Experimental Animals,
Kawasaki, Japan.
#228 Poster Board Number.......................................433
A NOVEL PARADIGM FOR ASSESSING
EFFICACIES OF POTENTIAL ANTIDOTES
AGAINST NEUROTOXINS IN MICE. D.
L. Crankshaw 1,2,3 , D. J. Goon 1,2 , J. E. Briggs 1 , D.
DeLong 2 , M. Kuskowski 2 , S. E. Patterson 1 and H. T.
Nagasawa 1,2 . 1 Center for Drug Design, University of
Minnesota, Minneapolis, MN, 2 VA Research Service
151, VA Medical Center, Minneapolis, MN and
3
Department Food Science and Nutrition, University
of Minnesota, St. Paul, MN. Sponsor: P. Hanna.
#229 Poster Board Number.......................................434
NON-INVASIVE MOUSE GENOTYPING
USING DNA ISOLATED FROM FECAL
SAMPLES. M. M. Ralston, K. D. Bongiovanni and
C. V. Smith. Seattle Children’s Hospital Research
Institute, Center for Developmental Therapeutics,
Seattle, WA.
#230 Poster Board Number.......................................435
UNANTICIPATED ANTICOAGULANT
RESPONSE TO UNFRACTIONATED
HEPARIN IN CYNOMOLGUS MONKEYS
MEASURED BY ACTIVATED CLOTTING
TIME. P. Beaumier, M. Bauman, T. Dawe, J. Tilton,
R. Coxen and D. Hayward. Safety Assessment,
SNBL USA, Everett, WA. Sponsor: M. Osier.
#231 Poster Board Number.......................................436
INTRACELLULAR ACIDIFICATION
PROMOTES ALLOXAN-INDUCED
TOXICITY IN PANCREATIC ISLETS. J. P.
Gray 1 , E. Heart 2 , K. Fussell 1 , S. Jamil 3 , P. J. Smith 2
and J. D. Laskin 3 . 1 Pharmacology & Toxicology,
Rutgers University, Piscataway, NJ, 2 Biocurrents
Research Center, Marine Biological Laboratory,
Woods hole, MA and 3 Environment & Occupational
Medicine, UMDNJ-Robert Wood Johnson Medical
School, Piscataway, NJ.
#232 Poster Board Number.......................................437
THE QUANTIFICATION OF STRUCTURAL/
FUNCTIONAL IMPAIRMENT IN THE
EXPERIMENTAL DOG OSTEOARTHRITIS
MODEL IS A USEFUL TOOL FOR DRUG
TESTING. E. Troncy 1,3 , M. Moreau 1 , M. D’Anjou 1 ,
F. Duguay 2 , S. Authier 2,1 , C. Boileau 1,3 , J. Martel-
Pelletier 1,3 , F. Abram 3 , J. Raynauld 1,3 and J.
Pelletier 1,3 . 1 Université de Montréal, Saint-Hyacinthe,
QC, Canada, 2 LAB Research Inc., Laval, QC,
Canada and 3 ArthroLab Inc., Montreal, QC, Canada.
Sponsor: G. Washer.
#233 Poster Board Number.......................................438
TOXICITY OF INTRAVENOUSLY
ADMINISTERED ACIDIC AND ALKALINE
VEHICLE FORMULATIONS IN MICE. S.
A. Shah, L. S. Krsmanovic, P. I. Atkins and E. A.
Zahalka. Mammalian Toxicology, BioReliance,
Rockville, MD.
104
SOT’s 47 th Annual Meeting