Annual Meeting Program - Society of Toxicology

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Society of Toxicology 2008 Program Description (Continued) Abstract # #2181 Poster Board Number.......................................320 METHYL 2-CYANO-3, 11-DIOXO-OLEAN-1, 12-DIEN-30-OATE (CDODA-ME) IS HIGHLY CYTOTOXIC TO PANCREATIC CANCER CELLS. I. Jutooru 1 , G. Chadalapaka 1 , S. Chintharlapalli 2 , S. Papineni 1 and S. Safe 1,2 . 1 Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX and 2 Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX. #2182 Poster Board Number.......................................321 CURCUMIN INHIBITS BLADDER CANCER CELL GROWTH BY TARGETING THE SPECIFICITY FACTORS BY BOTH PROTEASOME-DEPENDENT AND PROTEASOME-INDEPENDENT MECHANISMS. G. Chadalapaka 1 , I. Jutooru 1 , S. Chintharlapalli 2 , S. Papineni 1 and S. Safe 1,2 . 1 Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX and 2 Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX. #2183 Poster Board Number.......................................322 GUGGULSTERONE, A CONSTITUENT OF INDIAN AYURVEDIC MEDICINAL PLANT COMMIPHORA MUKUL, INHIBITS ANGIOGENESIS IN VITRO AND IN VIVO. S. V. Singh and D. Xiao. Pharmacology, University of Pittsburgh, Pittsburgh, PA. Thursday Morning, March 20 8:30 AM to 12:00 NOON Ballroom 6C & E POSTER SESSION: FISH ALTERNATIVE MODELS OF TOXICITY Chairperson(s): Jai Dwivedi, University of Texas Medical Branch, Galveston, TX and Sumitra Sengupta, Oregon State University, Corvallis, OR. Displayed: 8:30 AM–12:00 NOON Attended: 10:15 AM–12:00 NOON #2184 Poster Board Number.......................................325 MORPHOLINO KNOCKDOWN OF CYP1A EXACERBATES CARDIAC DEFORMITIES IN b-NAPHTHOFLAVONE DOSED FUNDULUS HETEROCLITUS. B. Clark 1 , C. Matson 1 , C. Fleming 1 , M. Jenny 2 , M. Hahn 2 and R. Di Giulio 1 . 1 Duke University, Durham, NC and 2 Woods Hole Oceanographic Institute, Woods Hole, MA. #2185 Poster Board Number.......................................326 LIVER TOXICITY AND REGENERATION: THE USE OF A SMALL FISH MODEL – JAPANESE MEDAKA. A. J. Bernal, B. Yuen and D. Hinton. Integrated Toxicology and Environmental Health Program, Nicholas School of Environment and Earth Sciences, Duke University, Durham, NC. Abstract # #2186 Poster Board Number.......................................327 A MULTIFACETED, MEDIUM- THROUGHPUT APPROACH USING ZEBRAFISH FOR DETECTING DEVELOPMENTAL NEUROTOXICITY. J. Cowden, B. Padnos, D. L. Hunter, R. MacPhail, K. Jensen and S. Padilla. Neurotoxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, NC. #2187 Poster Board Number.......................................328 IMPROVED DIFFERENTIAL DISPLAY ANALYSIS BASED ON DEGENERATE OLIGONUCLEOTIDE-PRIMED PCR. H. Teraoka, K. Igarashi, S. Itoh, A. Ogawa, A. Kubota, A. M. Elmagd, T. Hiraga and D. Endoh. School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan. #2188 Poster Board Number.......................................329 DRUG EFFECTS ON THE LOCOMOTOR ACTIVITY OF LARVAL ZEBRAFISH. T. D. Irons 2,1 , R. MacPhail 1 , D. L. Hunter 1 and S. Padilla 1 . 1 Neurotoxicology Divison, U.S. Environmental Protection Agency, Research Triangle Park, NC and 2 Curriculum in Toxicology, UNC-CH, Chapel Hill, NC. #2189 Poster Board Number.......................................330 CHARACTERIZATION OF LOCOMOTOR ACTIVITY OF ZEBRAFISH LARVAE: TEMPORAL VARIABILITY AND PHOTORESPONSE. J. Brooks 2 , R. MacPhail 1 , D. L. Hunter 1 , B. Padnos 1 and S. Padilla 1 . 1 Neurotoxicology Division, U.S. EPA, Res Tri Park, NC and 2 Division of Science and Mathematics, Brevard College, Brevard, NC. #2190 Poster Board Number.......................................331 DIFFERENCES IN THE STRUCTURE AND FUNCTION OF FATHEAD MINNOW AND HUMAN ERa: IMPLICATIONS FOR IN VITRO TESTING OF ENDOCRINE DISRUPTING CHEMICALS. C. V. Rider 1,2 , P. C. Hartig 2 , M. C. Cardon 2 and V. S. Wilson 2 . 1 Molecular Biomedical Sciences, NCSU, Raleigh, NC and 2 Reproductive Toxicology Division, U.S. EPA, ORD, NHEERL, RTP, NC. #2191 Poster Board Number.......................................332 ZEBRAFISH: A TOOL FOR EXAMINING THE EFFECTS OF SUB-ACUTE ALGAL TOXIN EXPOSURE IN THE VERTEBRATE CNS. K. A. Lefebvre 1 , S. Tilton 2 , T. Bammler 3 , R. Beyer 3 , P. Janssen 3 , F. Farin 3 , S. Srinouanprachanh 3 and E. Gallagher 2 . 1 Environmental Conservation, NOAA Fisheries/NWFSC, Seattle, WA, 2 Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA and 3 NIEHS Center for Ecogenetics and Environmental Health Functional Genomics and Bioinformatics Core Facilities, University of Washington, Seattle, WA. Thursday up-to-date information at www.toxicology.org 277
47 th Annual Meeting & ToxExpo Program Description (Continued) Thursday Abstract # Abstract # #2192 Poster Board Number.......................................333 IDENTIFICATION AND COMPARISON OF TWO ISOFORMS OF THE FARNESOID X RECEPTOR ALPHA IN JAPANESE MEDAKA (ORYZIAS LATIPES), A DEVELOPING BILIARY TOXICITY MODEL. D. L. Howarth 1,2 , D. E. Hinton 1,2 and S. W. Kullman 1,3 . 1 Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC, 2 Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC and 3 Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC. #2193 Poster Board Number.......................................334 MPTP (1-METHYL 4-PHENYL 1, 2, 3, 6-TETRAHYDROPYRIDINE) INDUCED NEURODEGENERATION IN DASYATIS SABINA (ATLANTIC STINGRAY). J. Dwivedi 1,2 , A. Montalvo 1 and C. Stevens 1 . 1 Preventative Medicine and Community Health, University of Texas Medical Branch, Galveston, TX and 2 Marine Biomedical Technologies Inc., Galveston, TX. #2194 Poster Board Number.......................................335 ARYL HYDROCARBON RECEPTOR REPRESSOR (AHRR): MECHANISTIC INSIGHTS FROM STUDIES IN MAMMALIAN AND NONMAMMALIAN MODELS. S. I. Karchner 1 , M. J. Jenny 1 , A. M. Tarrant 1 , B. R. Evans 1,2 , X. Yang 2 , D. H. Sherr 2 and M. E. Hahn 1 . 1 Woods Hole Oceanographic Institution, Woods Hole, MA and 2 Boston University, Boston, MA. #2195 Poster Board Number.......................................336 REDUCED SOX9B EXPRESSION BY TCDD IMPAIRS CRANIOFACIAL CARTILAGE GROWTH IN ZEBRAFISH EMBRYOS. K. M. Xiong 1 , R. E. Peterson 2 and W. Heideman 2,1 . 1 Biomolecular Chemistry, University of Wisconsin at Madison, Madison, WI and 2 School of Pharmacy, University of Wisconsin at Madison, Madison, WI. #2196 Poster Board Number.......................................337 CHEMICAL GENETICS TO IDENTIFY MOLECULAR PATHWAYS CONTROLLING TISSUE REGENERATION. S. Sengupta 1,2 , L. K. Mathew 1,2 and R. L. Tanguay 1,2 . 1 EMT, Oregon State University, Corvallis, OR and 2 EHSC, Oregon State University, Corvallis, OR. #2197 Poster Board Number.......................................338 INHIBITOR OF DNA BINDING-1 IS REQUIRED FOR NORMAL ZEBRAFISH CAUDAL FIN REGENERATION. C. Villano, T. Kung and L. White. Biochem and Micro, Rutgers University, New Brunswick, NJ. #2198 Poster Board Number.......................................339 ROLES OF ARYL HYDROCARBON RECEPTORS (AHR) AND AHR REPRESSORS IN DEVELOPMENT AND DEVELOPMENTAL TOXICITY OF TCDD. M. J. Jenny, S. I. Karchner, D. G. Franks, B. R. Woodin and M. E. Hahn. Biology, Woods Hole Oceanographic Institution, Woods Hole, MA. #2199 Poster Board Number.......................................340 SELDI PROTEINCHIP-BASED LIVER BIOMARKERS IN FUNGICIDE EXPOSED ZEBRAFISH. A. Bulman 1 , D. Bencic 2 , A. Biales 2 , R. Flick 2 , G. Ross 1 and D. Lattier 2 . 1 LSG, Bio-Rad, Hercules, CA and 2 ORD, NERL, EERD, U.S. EPA, Cincinnati, OH. Sponsor: T. Reddy. Thursday Morning, March 20 8:30 AM to 12:00 NOON Ballroom 6C & E POSTER SESSION: CARDIOVASCULAR SYSTEM: VASCULAR EFFECTS Chairperson(s): Bo Jiang, University of Washington, Seattle, WA and Judith Zelikoft, New York University School of Medicine, Tuxedo, NY. Displayed: 8:30 AM–12:00 NOON Attended: 8:30 AM–10:15 AM #2200 Poster Board Number.......................................341 VASCULAR DILATION AND ANEURYSM DETECTED BY NONINVASIVE HIGH- FREQUENCY ULTRASONOGRAPHY IN APOE DEFICIENT MICE INJECTED WITH ANGIOTENSIN II. E. Suzuki 1 , N. Shimoji 1 , S. Tomioka 1 , H. Kameda 1 , M. Kammueller 2 and Y. Nagae 1 . 1 Safety Profiling and Assessment, Novartis Pharmacology K.K., Tsukuba, Japan and 2 Safety Profiling and Assessment, Novartis Pharmacology AG, Basel, Switzerland. #2201 Poster Board Number.......................................342 INFLAMMATORY PROTEIN AND GENE EXPRESSION IN MONOCYTES AND MACROPHAGES EXPOSED TO CHOLESTEROL SECOALDEHYDE: IMPLICATIONS TO ATHEROSCLEROTIC PLAQUE DEVELOPMENT. A. C. Raghavamenon 1 , X. Gao 1 , O. D’Auvergne 2 , K. G. Kousoulas 3 and R. M. Uppu 1 . 1 Environmental Toxicology and the Health Research Center, Southern University and A & M College, Baton Rouge, LA, 2 Biological Sciences, Southern University and A & M College, Baton Rouge, LA and 3 Pathobilogical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA. #2202 Poster Board Number.......................................343 EFFECTS OF PRENATAL CIGARETTE SMOKE EXPOSURE ON LIPID PARAMETERS ASSOCIATED WITH OFFSPRING CARDIAC RISK: A STUDY IN MICE. J. T. Zelikoff 1 , S. P. Ng 1 , J. Lyon 1 , D. D. Bolanowski 2 , D. Conklin 2 and A. Bhatnagar 2 . 1 Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY and 2 Department of Medicine Division of Cardiology, University of Louisville, Louisville, KY. 278 SOT’s 47 th Annual Meeting
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Annual Meeting Program - Society of Toxicology

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