Annual Meeting Program - Society of Toxicology

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Society of Toxicology 2008 Program Description (Continued) Abstract # Wednesday Morning, March 19 7:30 AM to 8:50 AM Room 602 Abstract # Wednesday Morning, March 19 7:30 AM to 8:50 AM Room 605 INFORMATIONAL SESSION: CROSS-CULTURAL UNDERSTANDING OF ASIAN AND WESTERN CULTURAL VALUES IN THE WORKPLACE Chairperson(s): Thomas Kawabata, Pfizer Global Research and Development, Groton, CT and Diana J. Auyeung-Kim, Charles River Laboratories Preclinical Services Nevada, Sparks, NV. Endorsed by: Association of Scientists of Indian Origin Special Interest Group Career Resource and Development Committee Korean Toxicologists Association in America Special Interest Group* The competition in developing your career as a scientist can be daunting at times. It is clear that being productive through hard work alone is not the answer. In order to meet your career goals, scientists must also develop leadership and people skills. The mastering of these skills may be particularly challenging for those scientists reared with cultural values that differ from their western workplace culture. The differences in cultural values may be manifested in misunderstanding and barriers or “glass ceilings” in the development of one’s career. Asian scientists and their co-workers and managers need to better understand how Asian and Western cultural values differ and how such cultural values are directly connected to behavior and practices in the workplace. Many Asians for example, are taught to respect authority, not to toot their own horn and value harmony of the team. It is also important to understand of how different behaviors are perceived by their non-Asian managers and co-workers in the Western workplace and the potential impact that may ensue when behaviors are misunderstood. For instance, not speaking up in team meetings may be perceived as being not interested or having nothing valuable to add to the discussion. These misperceptions may result in organizations underutilizing their Asian employees and decreased team effectiveness. In addition, Asian scientists may experience limited upward mobility and lower job satisfaction. This background information will be covered by Sally Huang-Nissen, a consultant and trainer with extensive experience in the area of cross-cultural effectiveness and diversity training. This will be followed by a roundtable discussion by a panel of SOT members from different backgrounds and with different career paths (academia, industry, government). The roundtable discussion will focus on their personal experiences and how these scientists addressed these cultural differences in their careers. #1329 7:30 CROSS CULTURAL UNDERSTANDING OF ASIAN AND WESTERN VALUES IN THE WORKPLACE. T. Kawabata 1 and D. Auyeung- Kim 2 . 1 Pfizer, Groton, CT and 2 Charles River Laboratories, Sparks, NV. 7:35 INDIAN PERSPECTIVE. Madhu Soni 7:45 UNDERSTANDING ASIAN CULTURAL VALUES AND POTENTIAL IMPACT IN THE WESTERN WORKPLACE. Sally Huang-Nissen 7:55 KOREAN PERSPECTIVE. Byong Han Chin 8:05 CHINESE PERSPECTIVE. Fengju Bai 8:15 PERSPECTIVES FROM A NON-ASIAN THAT WORKED IN ASIA. Karen Blackburn 8:25 PANEL DISCUSSION. INFORMATIONAL SESSION: TOXICOLOGICAL AND PUBLIC HEALTH CHALLENGES IN AFRICA Chairperson(s): Sanmi Areola, Nashville Metro Public Health Department, Nashville, TN and Abdel Razak Kadry, U.S. EPA, Washington, DC. Endorsed by: Food Safety Specialty Section Risk Assessment Specialty Section* Paucity of data and lack of information exchange present major challenges to identifying feasible risk management options for toxicological challenges in Africa. The associated consequences are typified by current global health initiatives that are unintentionally excluding toxicological and public health concerns pertinent to the African continent. For example, concerns about nanoproducts may not be as relevant to Africans as would exposure to cyanide from widespread consumption of cassava as a staple food source. Two-thirds of the 900 million sub-Saharan Africans live in rural areas and rely on agriculture and other natural resources for sustenance causing shrinkage in the environmental resource base of the region. The resultant decline in biodiversity imposes an enormous strain on food safety, which frequently leads to dependence on food sources tainted with toxicants. In addition, large volumes of industrial chemicals associated with growth in the petro-chemical, agro-chemical, textile, mining, and food preservation industries raise concerns on their short- and long-term effects. Oil pollution is an important and controversial subject of discussion in Africa. The public health impacts of new pharmaceuticals such as anti-retroviral drugs, new classes of anti-malarial drugs, and the growing problems of illicit drug dumping in Africa are largely unknown. Most countries lack the resources needed to conduct relevant human health risk assessment and for making environmental risk management decisions. This session provides a platform to bridge the gaps by highlighting some specific toxicological problems facing the continent, engaging scientists conducting global health researches, and bringing to the table individuals who have been part of risk management practices in the developed countries. It is hoped that feasible approaches that take into consideration Africa’s geopolitical and cultural divides will be identified, discussed and prioritized to guide future interventions. #1330 7:30 TOXICOLOGICAL AND PUBLIC HEALTH CHALLENGES IN AFRICA. S. Areola. Metro Public Health Department, Nashville, TN. 7:32 TOXICOLOGY IN THE AFRICAN CONTEXT. Peter Spencer 7:42 MYCOTOXINS IN AFRICA: WHAT DO WE KNOW? Edmond Creppy 7:52 EFFECTS OF URBANIZATION AND RAPID INDUSTRIAL DEVELOPMENT ON HEAVY METAL LEVELS IN WATER, PLANT, AND FISH AROUND GREATER CAIRO, EGYPT. Osama El-Tawil 8:02 THE ENVIRONMENTAL, POLITICAL, AND SOCIOECONOMIC CONSEQUENCES OF OIL PRODUCTION IN THE NIGER DELTA REGION OF NIGERIA. Chuck Okereke 8:12 IDENTIFYING AND PRIORITIZING OPTIONS FOR ADDRESSING TOXICOLOGICAL CHALLENGES IN AFRICA. Sanmi Areola Wednesday up-to-date information at www.toxicology.org 205
47 th Annual Meeting & ToxExpo Program Description (Continued) Abstract # Wednesday Morning, March 19 8:00 AM to 8:50 AM Ballroom 6A Wednesday Morning, March 19 8:30 AM to 9:30 AM Exhibit Hall 4C-4 Wednesday Keynote Medical Research Council (MRC) Lecture: Biological Energy Conversion and its Toxic Consequences Lecturer: Nobel Laureate Sir John E. Walker, MRC Dunn Human Nutrition Unit, Cambridge, UK Energy in foodstuffs is released by respiration (controlled burning), consuming in the process most of the oxygen that we have breathed in. Of the 1000 or so proteins that are involved, about 100 of them are organized into the respiratory enzyme complexes in mitochondria that function as molecular machines to convert the redox energy derived from food-stuffs into adenosine triphosphate (ATP), the energy currency of biology. The final synthetic step is achieved by a remarkable molecular machine that has a mechanical rotary action. An important toxic by-produce of energy conversion is the production of ROS reactive oxygen species (ROS). ROS are generated during the process of electron transfer, but where and how they are generated remains controversial. The ROS can react with nucleic acids, proteins and phospholipids causing damage to biological processes that may lead to diseases and contribute to ageing. Hence, there is a need to develop drugs to prevent the toxic effects of ROS. All of these issues will be discussed in the lecture. Wednesday Morning, March 19 8:30 AM to 9:30 AM Exhibit Hall 4C-3 Exhibitor Hosted Session: Automated In Vivo Sampling with Culex Presented by: BASi (Bioanalytical Systems, Inc.) Culex is a modular system for programmed blood and bile sampling, microdialysis, infusions and physiological measurements. This presentation will outline the basics of automated sampling and how the Culex, a unique instrument, gets the job done 24/7, using freely-moving animals. You will learn the differences between manual and automatic sampling and dosing, and how multiple data streams from a single animal can be obtained at one time. Exhibitor Hosted Session: Multiplex Gene Expression for Toxicology Screening of Target Compounds Presented by: Beckman Coulter, Inc. Detection of cellular response in toxicological studies requires a comprehensive detection platform that can analyze multiple relevant pathways in a cost-effective manner. Multiplex gene expression can be employed to look at various metabolic, cell signaling, or user defined pathways simultaneously. The Beckman Coulter GeXP Genetic Analysis platform delivers high throughput gene expression using a simplified chemistry to allow same day sample to answers. Wednesday Morning, March 19 9:00 AM to 11:45 AM Room 605 Developmental Basis of Disease SYMPOSIUM SESSION: DEVELOPMENTAL BASIS OF HEALTH AND DISEASE: PERSISTENT EFFECTS OF TOBACCO SMOKE EXPOSURE (iat) Chairperson(s): Laura Van Winkle, University of California Davis, Davis, CA and Kent Pinkerton, University of California Davis, Davis, CA. Endorsed by: Immunotoxicology Specialty Section Inhalation and Respiratory Specialty Section* Reproductive and Developmental Toxicology Specialty Section Toxicologic and Exploratory Pathology Specialty Section Children are exposed to tobacco smoke. In a study of 5, 400 U.S. school aged children, 85% had measurable cotinine levels in their blood. Whether it is prenatal exposure to mainstream smoke or postnatal exposures to sidestream smoke, childhood exposures are most often involuntary exposures and can result in adverse health effects. This is not surprising as tobacco smoke contains a complex mixture of compounds with toxic and/or bioactive effects. Yet the long term outcomes of childhood exposures are still not well understood. The purpose of this session is to bring together the latest research on the effect of tobacco smoke on development of the neural, immune and respiratory systems and to highlight potential areas of future research. There is recent concern about the possibility of persistent adverse health effects of tobacco smoke exposure that continue into adulthood after exposures during development in either the pre or postnatal period. Persistent effects have been described for the lung, the immune system and for both behavior and neurobiology. #1331 9:00 DEVELOPMENTAL EFFECTS OF HEALTH AND DISEASE: PERSISTENT EFFECTS OF TOBACCO SMOKE EXPOSURE. L. S. Van Winkle 1,3 and K. E. Pinkerton 1,2,3 . 1 Center for Health & the Environment, UC Davis, Davis, CA, 2 Med: Pediatrics, UC Davis, Davis, CA and 3 Vet:Med Anatomy, Physiology and Cell Biology, UC Davis, Davis, CA. #1332 9:05 EFFECTS OF ENVIRONMENTAL TOBACCO SMOKE ON THE DEVELOPING IMMUNE SYSTEM OF INFANT MONKEYS. K. E. Pinkerton, L. Wang and J. P. Joad. Center for Health and the Environment, University of California, Davis, Davis, CA. 206 SOT’s 47 th Annual Meeting
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