Annual Meeting Program - Society of Toxicology

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Society of Toxicology 2008 Program Description (Continued) Abstract # #1093 Poster Board Number.......................................431 AMBIENT PARTICULATE MATTER SUPPRESSES ALVEOLAR MACROPHAGE CYTOKINE RESPONSE TO LIPOPOLYSACCHARIDE. K. Sawyer 1 , M. C. Madden 2 and A. J. Ghio 2 . 1 Environmental Science and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC and 2 National Health Effects Research Laboratory, U.S. EPA, RTP, NC. #1094 Poster Board Number.......................................432 THE ROLE OF SPARC IN ASBESTOS- INDUCED PULMONARY FIBROSIS. A. M. Smartt, M. Brezinski, A. Brave Rock and E. A. Putnam. Biomedical & Pharmaceutical Sciences/ Center For Environmental Health Sciences, University of Montana, Missoula, MT. Sponsor: M. Pershouse. #1095 Poster Board Number.......................................433 TOXICOLOGIC EFFECTS OF ACUTE 1, 2-DICHLOROETHANE (ETHYLENE DICHLORIDE; EDC) INHALATION IN F344 RATS. J. A. Hotchkiss, K. A. Johnson, A. K. Andrus, S. M. Krieger and J. P. Maurissen. Toxicology, Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. #1096 Poster Board Number.......................................434 BIOAEROSOL EMISSIONS FROM COMPOSTING GROUNDS INDUCE CYTOTOXICITY AND INFLAMMATORY RESPONSES IN RAW264.7 MACROPHAGES. M. Roponen 1 , K. Huttunen 1 , H. Rintala 1 , P. Kaarakainen 1 , A. Nevalainen 1 and M. Hirvonen 1,2 . 1 Department of Environmental Health, National Public Health Institute, Kuopio, Finland and 2 Department of Environmental Science, University of Kuopio, Kuopio, Finland. Sponsor: M. Viluksela. #1097 Poster Board Number.......................................435 COMPARISON OF LUNG INJURY FOR JP-8 VERSUS S-8 JET FUELS AT THRESHOLD CONCENTRATIONS. M. McLaughlin, J. Vargas, R. Camponovo, S. S. Wong, K. Le and M. Witten. Center for Toxicology & Department of Pediatrics, The University of Arizona, Tucson, AZ. #1098 Poster Board Number.......................................436 EXTRAPULMONARY TISSUE DISTRIBUTION OF METALS FOLLOWING REPEATED LUNG EXPOSURES TO WELDING FUMES WITH DIFFERENT ELEMENTAL PROFILES. J. M. Antonini, J. R. Roberts, K. Sriram, S. A. Benkovic, J. P. O’Callaghan and D. B. Miller. NIOSH, Morgantown, WV. #1099 Poster Board Number.......................................437 DESIGN OF AN INHALATION EXPOSURE SYSTEM TO STUDY SPOT WELDING FUME CHARACTERISTICS AND BIOLOGICAL EFFECTS. A. A. Afshari, J. M. Antonini, V. Castranova, R. Boylstein, R. Kanwal and D. G. Frazer. NIOSH, Morgantown, WV. Abstract # #1100 Poster Board Number.......................................438 A NOVEL METHOD FOR THE CHEMICAL CHARACTERIZATION OF GENERATED JET FUEL VAPOR AND AEROSOL FOR ANIMAL STUDIES. R. T. Tremblay 1 , S. A. Martin 1 , L. D. Fechter 2 and J. W. Fisher 1 . 1 Environmental Health Science Department, University of Georgia, Athens, GA and 2 Loma Linda VA Medical Center, Loma Linda, CA. #1101 Poster Board Number.......................................439 SELECTIVITY OF NEUROPEPTIDE RELEASE FROM PULMONARY CAPSAICIN-SENSITIVE AFFERENTS IN RELATION TO DIESEL EXHAUST EXPOSURE. S. S. Wong 1 , N. N. Sun 1 , I. Keith 3 , C. Lantz 2 and M. Witten 1 . 1 Center for Toxicology & Department of Pediatrics, The University of Arizona, Tucson, AZ, 2 Center for Toxicology and Department of Cell Biology & Anatomy, The University of Arizona, Tucson, AZ and 3 School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI. #1102 Poster Board Number.......................................440 DETERMINATION OF CELL PROLIFERATION, APOPTOSIS AND CYTOKERATIN EXPRESSION IN THE EPITHELIUM OF THE DOG LARYNX. A. Postoyalko and C. M. Bray. Covance Laboratories Ltd, Harrogate, United Kingdom. Sponsor: D. Everett. Tuesday Afternoon, March 18 1:00 PM to 4:30 PM Exhibit Hall Stem Cell Biology AND Toxicology POSTER SESSION: SIGNAL TRANSDUCTION AND GENE REGULATION Chairperson(s): Heekyong Bae, Michigan State University, East Lansing, MI and Stacey Harper, Oregon State University, Corvallis, OR. Displayed: 1:00 PM–4:30 PM Attended: 1:00 PM–2:45 PM #1103 Poster Board Number.......................................501 CIGARETTE SMOKE CONDENSATE DOWNREGULATION OF LYSYL OXIDASE TRANSCRIPTION MEDIATED BY INACTIVATION OF NUCLEAR FACTOR I. W. Li, S. Gao, Y. Zhao, P. Toselli and P. Stone. Biochemistry, Boston University School of Medicine, Boston, MA. #1104 Poster Board Number.......................................502 COX-2 REGULATES NF-kB ACTIVATION VIA THE RHO-A/JNK/AP-1 SIGNALING AXIS IN RENAL TUBULE CELLS. M. E. Ellis, W. W. Polk, P. L. Simmonds, J. V. Kushleika and J. S. Woods. Environmental Health, University of Washington, Seattle, WA. Tuesday up-to-date information at www.toxicology.org 183
47 th Annual Meeting & ToxExpo Program Description (Continued) Tuesday Abstract # Abstract # #1105 Poster Board Number.......................................503 P38 MAP KINASE REGULATES SULFUR MUSTARD-INDUCED CYTOKINE PRODUCTION INDEPENDENT OF NF-kB AND P53 SIGNALING BUT DOES NOT REGULATE SULFUR MUSTARD-INDUCED CELL DEATH. A. L. Ruff and J. F. Dillman. Cell and Molecular Biology, USAMRICD, Aberdeen Proving Ground, MD. #1106 Poster Board Number.......................................504 PROTECTIVE EFFECT OF CAFFEIC ACID PHENETHYL ESTER ON TERT-BUTYL HYDROPEROXIDE-INDUCED OXIDATIVE HEPATOTOXICITY. Y. Chung 1 , J. Choi 2,3 , K. Lee 2,3 and H. Jeong 2,3 . 1 Division of Food Science, Jinju International University, Jinju, South Korea, 2 Pharmacy, Chosun University, Kwangju, South Korea and 3 Research Center for Proteineous Materials, Chosun University, Gwangju, South Korea. #1107 Poster Board Number.......................................505 METALLOTHIONEIN-III ENHANCES VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION THROUGH THE ACTIVATION OF HIF-1ALPHA. H. H. Kim 1,2 and H. Jeong 1,2 . 1 Pharmacy, Chosun University, Kwangju, South Korea and 2 Research Center for Proteineous Materials, Chosun University, Gwangju, South Korea. #1108 Poster Board Number.......................................506 OSTEOPONTIN REGULATES MOUSE VASCULAR SMOOTH MUSCLE CELL DIFFERENTIATION VIA AN EXTRACELLULAR SIGNALING TRANSDUCTION PATHWAY. H. Gao 1 , M. C. Steffen 1 , T. Fan 2 and K. S. Ramos 1 . 1 Biochemistry, University of Louisville, Louisville, KY and 2 Chemistry, University of Louisville, Louisville, KY. #1109 Poster Board Number.......................................507 GENE EXPRESSION DIFFERENCES IN P53- DEFICIENT DAY-9 MOUSE EMBRYOS. H. Hosako, G. S. Martin, M. Barrier, S. H. Safe and P. E. Mirkes. Veterinary Physiology & Pharmacology, Texas A&M University, College Station, TX. #1110 Poster Board Number.......................................508 TCDD DISRUPTS THE WNT SIGNALING PATHWAY IN THE DEVELOPING MOUSE KIDNEY. E. MacAulay 1,2 , P. C. Boutros 3 and P. A. Harper 2,3 . 1 Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada, 2 Development & Stem Cell Biology, Hospital for Sick Children, Toronto, ON, Canada and 3 Pharmacology, University of Toronto, Toronto, ON, Canada. Sponsor: D. Grant. #1111 Poster Board Number.......................................509 TCDD ALTERS VASCULAR REMODELING IN RAT PLACENTA. R. Ishimura 2 , T. Kawakami 2 , S. Ohsako 1,2 and C. Tohyama 1,2 . 1 Division of Environment Health Sciences, CDBIM, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan and 2 Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Japan. #1112 Poster Board Number.......................................510 EPIGALLOCATECHIN-3-GALLATE PREVENTS OBESITY-RELATED FATTY LIVER BUT IS HEPATOTOXIC AT HIGH DOSES. J. D. Lambert 1 , M. Bose 1 , S. Sang 1 , J. Ju 1 , K. R. Reuhl 2 and C. S. Yang 1 . 1 Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ and 2 Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Piscataway, NJ. #1113 Poster Board Number.......................................511 TOXIC ENDOVANILLOID ACCUMULATION IN THE LUNG LEADS TO TRPV1- MEDIATED ER STRESS AND ACUTE LUNG INJURY. K. C. Thomas, C. E. Deering, G. S. Yost and C. A. Reilly. Pharmacology and Toxicology, University of Utah, Salt Lake City, UT. #1114 Poster Board Number.......................................512 EFFECT OF OLEANDRIN ON BINDING AND ACTIVITY OF NA-K-ATPASE IN CRUDE CARDIAC MEMBRANE PREPARATION. A. K. Tiwary 1,2,3 , B. Puschner 1,2,3 and I. N. Pessah 1,3 . 1 Graduate Group in Pharmacology and Toxicology, University of California, Davis, CA, 2 California Animal Health and Food Safety Laboratory, University of California, Davis, CA and 3 Veterinary Molecular Biosciences, University of California, Davis, CA. #1115 Poster Board Number.......................................513 CHANGES IN MITOGEN-ACTIVATED PROTEIN KINASE IN CEREBELLAR GRANULE NEURONAL CULTURES BY POLYBROMINATED DIPHENYL ETHERS. C. Fan 2,1 and P. R. Kodavanti 1 . 1 Neurotoxicology Division, U.S. EPA, RTP, NC and 2 Curriculum in Toxicology, University of North Carolina, Chapel Hill, NC. #1116 Poster Board Number.......................................514 EFFECT OF GINSENOSDIES RD AND RF ON ALTERING INTRACELLULAR GLUTATHIONE METABOLISM OF C6 GLIOMA CELLS. W. Y. Ng and M. S. Yang. Biology, Hong Kong Baptist University, Kowloon, Hong Kong, China. #1117 Poster Board Number.......................................515 BREVETOXIN-INDUCED BRONCHOCONSTRICTION AND ANTAGONISM IS MODULATED BY THE ANTIPARALLEL CHARACTER OF SYNTHETIC SIDE CHAINS: CHARACTERISTICS FOR SUCCESSFUL PULMONARY DRUG DESIGN. D. Baden 1 , S. Michelliza 1 , M. Wolf 1 , H. Jacocks 1 and W. Abraham 2 . 1 Center for Marine Science, UNCW, Wilmington, NC and 2 Department of Research, Mount Sinai Medical Center, Miami Beach, FL. #1118 Poster Board Number.......................................516 COMPARISON OF GENE EXPRESSION PROFILES IN LIVER OF RATS TREATED WITH RIDDELLIINE AND COMFREY. N. Mei 1 , L. Guo 2 , S. L. Dial 2 , J. C. Fuscoe 2 and T. Chen 1 . 1 Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, Jefferson, AR and 2 Division of Systems Toxicology, NCTR, Jefferson, AR. 184 SOT’s 47 th Annual Meeting
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