Annual Meeting Program - Society of Toxicology

Society of Toxicology 2008
Program Description (Continued)
Abstract #
#1014 Poster Board Number.......................................232
PREDICTING LACTATIONAL AND
EARLY POST-WEANING EXPOSURES
IN RATS USING BIOLOGICALLY BASED
PHARMACOKINETIC MODELING. M.
Yoon 1 and H. A. Barton 2 . 1 Research Associateship
Program, National Research Council, RTP, NC and
2
National Center for Computational Toxicology, U.S.
Environmental Protection Agency, RTP, NC.
#1015 Poster Board Number.......................................233
UTILIZING PK/PD RELATIONSHIPS FOR
INHIBITION OF SOD1 EXPRESSION IN
BRAIN AND SPINAL CORD (CNS) OF RATS
AND MONKEYS TO PREDICT HUMAN ASO
DOSE. R. S. Geary 1 , G. Hung 1 , S. P. Henry 1 , R.
Boyd 2 and F. Bennett 1 . 1 ISIS Pharmaceuticals, Inc,
Carlsbad, CA and 2 Northern Biomedical Research,
Inc., Muskegon, MI.
#1016 Poster Board Number.......................................234
PHYSIOLOGICALLY-BASED
PHARMACOKINETIC MODELING OF AN
ALKYLBENZENE MIXTURE IN CHILDREN
OF VARIOUS AGE GROUPS. T. Adamou 2 , S.
Haddad 1 and K. Krishnan 2 . 1 Biological sciences,
Université du Québec à Montréal, Montreal, QC,
Canada and 2 GRIS/TOXHUM, Université de
Montréal, Montreal, QC, Canada.
#1017 Poster Board Number.......................................235
PBPK MODELS FOR MIXTURES OF
DIOXIN-LIKE CHEMICALS. M. Easterling 1 ,
N. J. Walker 2 , F. M. Parham 2 and C. J. Portier 2 .
1
Constella Group, Durham, NC and 2 National
Institute of Environmental Health Sciences, RTP,
NC.
#1018 Poster Board Number.......................................236
EFFECT OF DYNAMIC BLOOD
PARTITIONING DURING LATE GESTATION
ON CHLORPYRIFOS DOSIMETRY. T. S.
Poet 1 , E. Lowe 2 , J. L. Mattsson 2 , M. J. Bartels 2 and
C. Timchalk 1 . 1 Biological Monitoring and Modeling,
Pacific Northwest Nat’l Lab, Richland, WA and 2 The
Dow Chemical Company, Midland, MI.
#1019 Poster Board Number.......................................237
A DISCRETE TIME MODEL TO ANALYZE
THE EFFECTS OF TOXICANTS ON THE
GROWTH OF C. ELEGANS NEMATODES
IN A MEDIUM THROUGHPUT SETTING. M.
Smith 1 , W. Boyd 2 , S. McBride 3 , G. Kissling 2 , J. H.
Freedman 2,3 and C. Portier 2 . 1 Constella, Durham,
NC, 2 National Institutes of Health (NIH)/National
Institute of Environmental Health Sciences(NIEHS)/
Laboratory of Molecular Toxicology, Research
Triangle Park, NC and 3 Duke University/Nicholas
School of the Environment and Earth Sciences,
Durham, NC.
#1020 Poster Board Number.......................................238
THE DEVELOPMENT OF A MULTISCALE
CARDIAC MODEL OF NANOPARTICLE
DRIVEN ATHEROSCLEROSIS. J. P. Carson, D.
R. Einstein, A. P. Kuprat and K. R. Minard. Pacific
Northwest National Laboratory, Richland, WA.
Sponsor: C. Timchalk.
Abstract #
#1021 Poster Board Number.......................................239
DIMENSIONAL ANALYSIS TO PREDICT
THE SPECIFIC ISOFORMS INVOLVED IN
BINDING CYP SUBSTRATES. B. Reisfeld 1,3 ,
P. N. Ciesielski 2 and A. N. Mayeno 3 . 1 Chemical and
Biological Engineering, Colorado State University,
Fort Collins, CO, 2 Interdisciplinary Program in
Materials Science, Vanderbilt University, Nashville,
TN and 3 Environmental and Radiological Health
Sciences, Colorado State University, Fort Collins,
CO.
#1022 Poster Board Number.......................................240
AN UPDATED METHODOLOGY TO
PREDICT RATES OF CYTOCHROME
P450 MEDIATED HYDROXYLATION OF
ALIPHATIC SUBSTRATES. A. N. Mayeno 1 ,
R. Yang 1 and B. Reisfeld 2,1 . 1 Environmental and
Radiological Health Sciences, Colorado State
University, Fort Collins, CO and 2 Chemical and
Biological Engineering, Colorado State University,
Fort Collins, CO.
Tuesday Afternoon, March 18
1:00 PM to 4:30 PM
Exhibit Hall
Nanotechnology
POSTER SESSION: NANOPARTICLES: TARGET ORGANS
Chairperson(s): Margaret Kraeling, U.S. Food and Drug Adminstration,
College Park, MD.
Displayed: 1:00 PM–4:30 PM
Attended: 2:45 PM–4:30 PM
#1023 Poster Board Number.......................................301
ANALYSIS OF DERMAL PENETRATION
OF TITANIUM DIOXIDE (TIO2)
FROM SUNSCREEN FORMULATIONS
CONTAINING MICRON- AND NANO-
SCALE PARTICLES OF TIO2. N. Sadrieh 1 ,
A. M. Wokovich 2 , N. V. Gopee 3 , P. H. Siitonen 3 ,
C. R. Cozart 3 , P. C. Howard 3 , W. H. Doub 2 and L.
F. Buhse 2 . 1 FDA/CDER/OPS, Silver Spring, MD,
2
FDA, Saint Louis, MO and 3 FDA, Jefferson, AR.
#1024 Poster Board Number.......................................302
THE TOXICITY AND BIOCOMPATIBILITY
OF NANOMATERIALS IN HUMAN
KERATINOCYTES (HACAT CELLS). N.
M. Schaeublin 1 , J. J. Schlager 1 , S. M. Hussain 1 ,
J. M. Miller 2 , G. R. Johnson 3 and D. M. Eby 3 .
1
Applied Biotechnology Branch, RHPB, Air Force
Research Labs, Wright Patterson, OH, 2 Department
of Chemistry, University Of Oregon, Eugene, OR
and 3 Airbase Sciences Branch, Materials Science
Directorate, Air Force Research Labs, Tyndall, FL.
#1025 Poster Board Number.......................................303
THE ROLE OF SIZE IN TITANIUM DIOXIDE
DERMAL NANOTOXICITY. S. M. Hussain 1 ,
L. K. Braydich-Stolle 1 , N. M. Schaeublin 1 , R.
C. Murdock 1 , D. R. Mattie 1 , A. M. Schrand 1 , J.
J. Schlager 1 , J. Jiang 2 and P. Biswas 2 . 1 Applied
Biotechnology Branch, RHBP, Air Force Research
Labs, Wright Patterson, OH and 2 Department Of
Chemical Engineering, Washington University in St.
Louis, St. Louis, MO.
Tuesday
up-to-date information at www.toxicology.org 177