Annual Meeting Program - Society of Toxicology

47 th Annual Meeting & ToxExpo
Program Description (Continued)
Abstract # Abstract #
THURSDAY MORNING
Thursday Morning, March 20
7:30 AM to 8:50 AM
Ballroom 6B
ISSUES SESSION: 2007 National Research Council-
National Academy of Sciences Reports: Impact on
the Future of Toxicology
Chairpersons: Gerald N. Wogan, Massachusetts Institute of Technology,
Cambridge, MA and Cheryl Lyn Walker, University of Texas MD
Anderson Cancer Center, Smithville, TX.
Endorsed by: SOT Presidential Chain
This special session has been organized by the 2008 Program Committee
to introduce SOT members to the 2007 National Research Council reports
from the National Academy of Science addressing key issues impacting
our society and profession today. This session will open dialogue on the
contents of the reports and their implications for the future of Toxicology.
An Introduction by the Session Chairs will be followed by presentations
from Chairs of the Committees drafting the three reports to be featured,
with a facilitated discussion to follow. These reports are:
Toxicity Testing in the 21 st Century: A Vision and Strategy, Daniel
Krewski, University of Ottawa, Ontario, Canada
Applications of Toxicogenomics Technologies to Predictive Toxicology
and Risk Assessment, David Christiani, Harvard University, Boston, MA
Models in Environmental Regulatory Decision Making, Chris Whipple,
ENVIRON Corporation, Emeryville, CA
combustion, with an emphasis on biodiesel exhaust as one of the better
studied biofuels. Comparison to emissions from petroleum diesel engines
will allow assessment as to how similar the emissions may be in terms of
toxic components, assisting in risk assessment for biodiesel exhaust; 3. to
present an overview of the known toxicology of biofuel emissions, with
reference to petroleum diesel exhaust literature, to identify areas where
assessment of the effects of biofuel emissions exposure should be pursued.
[This abstract may not reflect EPA policy.]
#2044 7:30 BIOFUEL COMBUSTION: AN EMERGING
HEALTH PROBLEM? M. C. Madden 1 and F.
Cassee 2 . 1 ORD, NHEERL, HSD, Clinical Research
Branch, U.S. EPA, Chapel Hill, NC and 2 Center of
Environmental Health Research, National Institute
for Public Health and Environment, Bilthoven,
Netherlands.
7:38 LIQUID BIOFUELS: BIOLOGICAL
SOURCES, RATIONALE FOR
DEVELOPMENT, AND THE OUTLOOK
FOR FUTURE USE IN THE U.S. Christopher
Somerville
7:56 COMBUSTION EMISSIONS FROM LIQUID
BIOFUELS. Robert McCormick
8:14 THE PRODUCTION AND USE OF LIQUID
BIOFUELS: SOME OBSERVATIONS FROM A
EUROPEAN PERSPECTIVE. Flemmee Cassee
8:32 THE TOXICOLOGY OF BIOFUELS
COMBUSTION EMISSIONS. Michael Madden
Thursday Morning, March 20
8:30 AM to 12:00 NOON
Ballroom 6C & E
Oxidative Signaling And Redox Biology
Thursday
Thursday Morning, March 20
7:30 AM to 8:50 AM
Room 608
ROUNDTABLE SESSION: BIOFUEL COMBUSTION: AN
EMERGING HEALTH PROBLEM?
Chairperson(s): Michael Madden, U.S. EPA, Chapel Hill, NC and
Flemming Cassee, National Institute for Public Health & Environment,
Bilthoven, Netherlands.
Endorsed by:
Inhalation and Respiratory Specialty Section*
Occupational and Public Health Specialty Section
Recently the concept of increasing the production of liquid biofuels for
energy use in the U.S. and other countries has stirred up debate. Liquid
biofuels have attracted attention as potential replacements for other liquid
petroleum-based fuels primarily, but not exclusively, in on-road vehicles.
Major uncertainties exist as to 1) the best biomass (e.g., corn, soy, etc.) to
utilize; the net energy balance (gain or loss) in the production and transport
of liquid biofuels; and 3) the market share liquid biofuels may attain.
Increased biofuel production has altered land use and created ethical
concerns, economic changes, and soil sustainability questions. Biofuel
combustion raises additional issues as to hazard identification of the emissions
produced under a wide range of conditions, such as fuel types and
blends, engine types and engine operating conditions, aftertreatments, etc.
To date few studies have been performed examining the health effects and
biological responses with exposures to biofuel emissions. The lack of toxicological
studies with biofuel emissions makes it difficult to assess the toxicity
of this class of fuel relative to other petroleum-based fuels, or other potential
fuels, e.g., hydrogen. This discussion session has these goals: 1) to inform
the audience of the potential for different biomass types being incorporated
into the global energy structure; 2) describe emission products of biofuel
POSTER SESSION: OXIDATIVE INJURY AND REDOX
BIOLOGY II: IN VITRO
Chairperson(s): Louise Ball, University of North Carolina Chapel Hill,
Chapel Hill, NC.
Displayed: 8:30 AM–12:00 NOON
Attended: 8:30 AM–10:15 AM
#2045 Poster Board Number.......................................101
MODULATION OF CELLULAR
ANTIOXIDANT ENZYMES ACTIVITIES AND
GLUTATHIONE LEVEL BY THE DRINKING
WATER CHLORINATION BY-PRODUCT,
DICHLOROACETATE. E. Hassoun and J. Mehta.
Pharmacology, The University of Toledo, Toledo,
OH.
#2046 Poster Board Number.......................................102
INCREASED MITOCHONDRIAL
THIOREDOXIN POTENTIATED
N-ETHYLMALEIMIDE-INDUCED
CYTOTOXICITY. Y. Chen 1 , Y. Go 2 , D. P. Jones 2
and J. Cai 1 . 1 Ophthalmology, Vanderbilt University,
Nashville, TN and 2 Medicine, Emory University,
Atlanta, GA.
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SOT’s 47 th Annual Meeting