Annual Meeting Program - Society of Toxicology

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Society of Toxicology 2008 Program Description (Continued) Abstract # #427 Poster Board Number.......................................334 ZEBRAFISH AS AN ALTERNATIVE MODEL TO ASSESS BIOMATERIAL NANOTOXICITY. O. Bar-Ilan, R. M. Albrecht, R. E. Peterson and D. Y. Furgeson. Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI. #428 Poster Board Number.......................................335 DIFFERENTIAL TOXICITY OF METALLIC NANOPARTICLES TO AQUATIC SPECIES. J. Griffitt 1 , J. Luo 1 , N. D. Denslow 1 , K. Powers 2 and D. S. Barber 1 . 1 Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL and 2 Particle Engineering Research Center, University of Florida, Gainesville, FL. #429 Poster Board Number.......................................336 A COMPARISON OF BULK AND NANO- SIZED ALUMINUM OXIDE (AL 2 O 3 ) ECOTOXICITY TO HYALELLA AZTECA AND TUBIFEX TUBIFEX IN SPIKED SEDIMENT. J. K. Stanley. U.S. Army Research and Devlopment Center, Vicksburg, MS. Sponsor: J. Steevens. #430 Poster Board Number.......................................337 THE EFFECTS OF METAL NANOPARTICLES AND FULLERENES ON OYSTER HEPATOPANCREAS CELLS AND EMBRYOS. A. H. Ringwood 1 , M. McCarthy 1 , T. Changela 1 , D. Carroll 2 and N. Levi 2 . 1 Biology, UNC - Charlotte, Charlotte, NC and 2 Physics, Wake Forest University, Winston-Salem, NC. #431 Poster Board Number.......................................338 DIFFERENTIAL AQUATIC TOXICITY RESPONSES OF GREEN ALGAE TO VARIOUS NANOPARTICLE-TYPES. C. M. Sayes, B. D. Ferrell, R. A. Hoke and D. B. Warheit. DuPont Haskell Laboratory, Newark, DE. #432 Poster Board Number.......................................339 FATE OF FULLERENE NANOPARTICLES AND THEIR INTERACTIONS WITH ORGANIC MATTERS IN AQUATIC ENVIRONMENTS. Y. Xia 1 , X. Q. Kong 2 and X. Xia 2 . 1 Dalian University of Technology, Dalian, China and 2 North Carolina State University, Raleigh, NC. #433 Poster Board Number.......................................340 AN EZ METRIC FOR EVALUATING NANOMATERIAL-BIOLOGICAL INTERACTIONS. S. L. Harper 1 , S. Lee 2 and R. L. Tanguay 1,3 . 1 Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 2 iFusion Laboratory, Department of Engineering, Oregon State University, Corvallis, OR and 3 Environmental Health Sciences Center, Oregon State University, Corvallis, OR. #434 Poster Board Number.......................................401 SCREENING ASSAYS FOR ASSESSING NANOPARTICLE TOXICITY. G. Oberdörster 2 , E. K. Rushton 2 and J. N. Finkelstein 1,2 . 1 Pediatrics, University of Rochester, Rochester, NY and 2 Environmental Medicine, University of Rochester, Rochester, NY. Abstract # #435 Poster Board Number.......................................402 LIVE-CELL ATTENUATED TOTAL REFLECTION - FOURIER TRANSFORM INFRARED SPECTROSCOPY (ATR-FTIR) OF THE CELLULAR RESPONSE ON EXPOSURE TO NANOMATERIALS. S. K. Sundaram, T. J. Weber, B. J. Riley, B. M. Webb- Robertson and R. S. Addleman. Pacific Northwest National Laboratory, Richland, WA. Sponsor: J. Pounds. #436 Poster Board Number.......................................403 INTEGRATION OF MICROARRAY AND PROTEOMIC DATA REVEALS PATHWAY- SPECIFIC INFLAMMATORY MARKERS OF NANOPARTICLE EXPOSURE TO MOUSE MACROPHAGES. S. Bandyopadhyay, L. Masiello, N. Karin, J. Jacobs, J. Pounds, B. Thrall and K. M. Waters. Environmental Biomarkers Initiative, PNNL, Richland, WA. #437 Poster Board Number.......................................404 CORRELATING TOXICITY OF NANOMATERIAL WITH PHYSICAL CHARACTERIZATION USING AN OXIDATIVE STRESS MODEL. M. Kovochich, T. Xia and A. E. Nel. Medicine, UCLA, Los Angeles, CA. #438 Poster Board Number.......................................405 NANOMATERIALS TOXICITY: CLASSIFICATION USING MULTI-CRITERIA DECISION ANALYSIS. I. Linkov 1 , T. Tervonen 2 , J. R. Figueira 2 , J. Steevens 3 and J. Kim 3 . 1 Carnegie Mellon University, Brookline, MA, 2 Technical University Lisbon, Lisbon, Portugal and 3 U.S. Army Corps of Engineers, Engineer Research and Development Center, Vicksburg, MS. #439 Poster Board Number.......................................406 ANALYSIS OF SIZE-DEPENDENT CELLULAR RESPONSES TO SILICA NANOPARTICLES FROM INTEGRATED GENOMIC AND PROTEOMIC DATA. B. Thrall, K. M. Waters, L. M. Masiello, B. J. Terasavich and R. C. Zangar. Pacific Northwest National Laboratory, Richland, WA. #440 Poster Board Number.......................................407 ENHANCED CYTO- AND GENOTOXIC EFFECTS OF FE(III) NANOPARTICLES COMPARED TO FE(III) FINE PARTICLES IN HUMAN LUNG CELLS. K. Bhattacharya 1 , E. Hoffmann 2 , C. Albrecht 3 , R. Schins 3 , G. Alink 4 and E. Dopp 1 . 1 Institute of Hygiene and Occupational Medicine, University of Duisburg-Essen, Essen, Germany, 2 Institute of Cell Biology, University of Rostock, Rostock, Germany, 3 Institut fuer Umweltmedizinische Forschung (IUF), Duesseldorf, Germany and 4 Wageningen University, Wageningen, Netherlands. #441 Poster Board Number.......................................408 SINGLE-WALLED CARBON NANOTUBES: GENO- AND CYTO-TOXIC EFFECTS IN LUNG FIBROBLAST V79 CELLS. E. Kisin 1 , A. Murray 1 , M. Keane 2 , X. Shi 2 , D. Schwegler- Berry 1 , O. Gorelik 3 , S. Arepalli 3 , V. Castranova 1,4 , W. Wallace 2 , V. Kagan 4 and A. Shvedova 1 . 1 PPRB, NIOSH, Morgantown, WV, 2 EAB, NIOSH, Morgantown, WV, 3 NASA-JSC, Houston, TX and 4 University of Pittsburgh, Pittsburgh, PA. Monday up-to-date information at www.toxicology.org 123
47 th Annual Meeting & ToxExpo Monday Program Description (Continued) Abstract # Abstract # #442 Poster Board Number.......................................409 A 28-DAYS REPEATED DOSE AND GENOTOXICTY STUDY OF SILVER NANOPARTICLES. Y. Kim 1 , J. Kim 1 , J. Kim 1 , J. Park 2 , H. Chang 3 , R. Im 2 , M. Song 1 , Y. Chung 4 and I. Yu 1 . 1 Biosafety Evaluation Headquarter, KEMTI, Incheon, South Korea, 2 College of Medicine, Chung- Ang University, Seoul, South Korea, 3 College of Medine, Kosin University, Busan, South Korea and 4 Center for Occupational Toxicology, KOSHA, Daejeon, South Korea. #443 Poster Board Number.......................................410 LIMITATIONS OF THE STANDARD IN VITRO GENOTOXICITY PROTOCOLS FOR TESTING OF NANOMATERIALS. M. Schulz 1 , W. Wohlleben 2 , B. van Ravenzwaay 1 and R. Landsiedel 1 . 1 Experimental Toxicology and Ecology, BASF, Ludwigshafen am Rhein, Germany and 2 Polymer Physics, BASF, Ludwigshafen am Rhein, Germany. Monday Afternoon, March 17 1:00 PM to 4:30 PM Exhibit Hall POSTER SESSION: KIDNEY Chairperson(s): Peter Goering, U.S. FDA, Silver Spring, MD. Displayed: 1:00 PM–4:30 PM Attended: 1:00 PM–2:45 PM #444 Poster Board Number.......................................411 ALTU-237: A 14-DAY ORAL TOXICITY STUDY IN BEAGLE DOGS. E. Koo 1 , G. Gesswein 1 , C. Godin 1 and K. Loveday 2 . 1 Bridge Global Pharmaceutical Services, Inc., Gaithersburg, MD and 2 Toxicology & Pharmacology, Altus Pharmaceuticals, Cambridge, MA. #445 Poster Board Number.......................................412 MECHANISTIC ASPECTS OF PROPANIL NEPHROTOXICITY IN VITRO. C. Racine 2 , A. Sweeney 1 , A. Kraynie 1 , S. Baksi 1 , D. Anestis 1 and G. O. Rankin 1 . 1 Pharmacology, Marshall University, Huntington, WV and 2 Davis & Elkins College, Elkins, WV. #446 Poster Board Number.......................................413 DETECTION OF ENDOTOXIN-INDUCED ACUTE KIDNEY INJURY IN RATS. R. P. Brown 1 , V. S. Vaidya 3 , B. C. Beach 1 , M. C. Toal 1 , S. T. Loftin 1 , J. Zhang 2 , F. B. Collings 3 , J. V. Bonventre 3 and P. L. Goering 1 . 1 CDRH, U.S. FDA, Silver Spring, MD, 2 CDER, U.S. FDA, Silver Spring, MD and 3 Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. #447 Poster Board Number.......................................414 ROLES OF MITOCHONDRIAL DYSFUNCTION, CASPASES, AND FAS RECEPTOR IN S-(1, 2-DICHLOROVINYL)- L-CYSTEINE (DCVC)-INDUCED CYTOTOXICITY IN HUMAN PROXIMAL TUBULAR (HPT) CELLS. L. H. Lash, F. Xu, D. A. Putt and I. Papanayotou. Pharmacology, Wayne State University Sch. Med., Detroit, MI. #448 Poster Board Number.......................................415 MITOCHONDRIAL GLUTATHIONE TRANSPORT IN DIABETIC NEPHROPATHY. Q. Zhong and L. H. Lash. Pharmacology, Wayne State University Sch. Med., Detroit, MI. #449 Poster Board Number.......................................416 PUROMYCIN TREATMENT RESULTED IN DIFFERENTIAL EXPRESSION OF GENES INVOLVED IN PATHWAYS ASSOCIATED WITH GENE/PROTEIN EXPRESSION PROCESS. A. R. Stapleton 1 and V. T. Chan 2 . 1 HJF, Wright-Patterson AFB, OH and 2 AFRL/HEPB, Wright-Patterson AFB, OH. Sponsor: J. Gearhart. #450 Poster Board Number.......................................417 ATTENUATION OF N-(3, 5-DICHLOROPHENYL)-2- HYDROXYSUCCINIMIDE-O-SULFATE (NSC)-INDUCED NEPHROTOXICITY IN PRIMARY CULTURES OF RAT RENAL PROXIMAL TUBULE CELLS. G. O. Rankin, C. Cook, S. L. Miles, S. K. Hong and D. K. Anestis. Pharmacology, Physiology & Toxicology, Marshall University, Huntington, WV. #451 Poster Board Number.......................................418 URINARY KIDNEY INJURY MOLECULE-1 AND N-ACETYL b-D-GLUCOSAMINIDASE AS BIOMARKERS FOR AMINOGLYCOSIDE AND CISPLATIN-INDUCED NEPHROTOXICITY IN PATIENTS. V. S. Vaidya, S. S. Waikar, F. B. Collings, K. Sunderland and J. V. Bonventre. Medicine-Renal, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. #452 Poster Board Number.......................................419 MODULATION OF OXIDATIVE STRESS BY RESVERATROL AND ATTENUTATION OF CISPLATIN IN VITRO RENAL TOXICITY. M. Valentovic and M. V. Terneus. Pharmacology, Physiology and Toxicology, Marshall University School of Medicine, Huntington, WV. #453 Poster Board Number.......................................420 GENE EXPRESSION ANALYSIS REVEALS NEW POSSIBLE MECHANISMS OF VANCOMYCIN-INDUCED NEPHROTOXICITY. H. H. Ng, C. Dieterich, A. Puey, S. Lin, R. Swezey, A. Furimsky, D. Fairchild and J. C. Mirsalis. BioSciences, SRI International, Menlo Park, CA. #454 Poster Board Number.......................................421 CHARACTERIZATION OF PROPIVERINE EFFECTS ON RAT PPARS. A. H. Heussner 1 , M. M. Baldock 1 , B. Manfred 2 and D. R. Dietrich 1 . 1 Human and Environmental Toxicology, University of Konstanz, Konstanz, Germany and 2 Preclinical and Clinical Safety, APOGEPHA GmbH, Dresden, Germany. #455 Poster Board Number.......................................422 THE POTENTIAL EFFECT OF MT-AB ON RENAL DYSFUNCTION WITHIN A CHINESE DIABETIC POPULATION. L. Lei 1,2 , L. Chen 1,2 , T. Jin 1,2,4 , M. Nordberg 3 and G. Nordberg 4 . 1 Occupational Health, Fudan University, Shanghai, China, 2 Toxicology, Fudan University, Shanghai, China, 3 Enviromental Medicine, Karolinska Institute, Stockholm, Sweden and 4 Public Health and Clinical Medicine, Umea University, Umea, Sweden. 124 SOT’s 47 th Annual Meeting
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