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Fibrate Mechanism of Action - The Center for Cholesterol Management

Fibrate Mechanism of Action - The Center for Cholesterol Management

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Fen<strong>of</strong>ibrate vs Fen<strong>of</strong>ibric Acid<br />

Unlike fen<strong>of</strong>ibrate fen<strong>of</strong>ibric acid contains a carboxylic acid<br />

moiety instead <strong>of</strong> an ester moiety.<br />

Fen<strong>of</strong>ibrate<br />

O<br />

Nonpolar ester Moiety<br />

O<br />

Cl<br />

O<br />

O<br />

O<br />

Cl<br />

Fen<strong>of</strong>ibric Acid<br />

O<br />

Polar Carboxylic<br />

Moiety<br />

O<br />

OH

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