Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Direct RCT at the Hepatocyte<br />
Hepatocyte<br />
RXR<br />
SR B1<br />
Hepatic Sinusoid<br />
PPARα<br />
Cholesteryl ester<br />
Free cholesterol<br />
Smaller alpha 3,4 HDL now<br />
available <strong>for</strong> relipidation or<br />
excretion<br />
ABCA1<br />
ABCG4<br />
ABCG5/8<br />
ABCB11<br />
Scavenger Receptor B1<br />
delipidation <strong>of</strong> large<br />
alpha 1 HDL<br />
Bile Duct