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Fibrate Mechanism of Action - The Center for Cholesterol Management

Fibrate Mechanism of Action - The Center for Cholesterol Management

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Fen<strong>of</strong>ibrate Intervention and Event Lowering in<br />

Diabetes (FIELD) Helsinki Cohort<br />

► Relative to placebo, the difference in HDL-C at 5 years<br />

was not significant.<br />

►Baseline HDL 2 -C was 0.46 mmol/L in both groups and<br />

there was a gradual decrease over time in fen<strong>of</strong>ibrate<br />

group (-21% at 2 years and -33% at 5 years, p

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