Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
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<strong>Fibrate</strong>s Increase ApoA-V Production<br />
VLDL<br />
Receptor<br />
Lipoprotein Lipase (LPL)<br />
apoA-V<br />
Apo C-II<br />
Apo E<br />
NEFA<br />
<strong>Fibrate</strong>s increase apoA-V<br />
production enhancing the<br />
anchoring <strong>of</strong> TG-rich<br />
lipoproteins like VLDL and<br />
chylomicrons at sites <strong>of</strong> LPL<br />
expression<br />
Schultze AE et al. J Lipid Res 2005;46:1591-95
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