Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Anti-inflammatory and<br />
Immunomodulatory Effects <strong>of</strong> PPARα<br />
Cell recruitment and<br />
activation<br />
<br />
PPARα activators<br />
decrease cell<br />
recruitment and<br />
activation<br />
MPC-1: Monocyte chemotactant protein-1<br />
CCR2: chemokine (c-c motif) receptor <strong>for</strong> CCL2 a<br />
monocyte & T-cell chemoattractant<br />
VCAM-1 (CD106): Vascular cell adhesion molecule-1<br />
ICAM-1 (CD54): Intracellular adhesion molecule<br />
Marx N, et al. Circulation. 1999;99:3125-3131 and Circ Res. 2004;94:1168-1178
Change language